Analogy of silicon and boron in plant nutrition.

Silicon (Si) and boron (B) are a class of elements called metalloids, which have properties like metals and non-metals. Si is classified as a quasi-essential element, while B is a micronutrient element for plants. Nowadays, numerous discoveries have shown the analogy of silicon and boron in plant nutrition. In this minireview, the molecular mechanisms for the transport of these two metalloids are compared. We also discussed the chemical forms of Si and B and their functional similarity in response to environmental stresses in plants. In conclusion, it can be proposed that cell wall-bound silicon rather than silica might partially replace boron for plant growth, development, and stress responses, and the underlying mechanism is the Si contribution to B in its structural function.

Bioequivalence of Blonanserin Tablets Under Fasting and Fed Conditions in Healthy Chinese Subjects.

Blonanserin is a novel oral antischizophrenic drug. Under fasting (n = 50) and fed (n = 60) conditions, this study compared the bioequivalence of the generic blonanserin tablet with the reference blonanserin tablet. In this single-center, randomized, open-label, 2-period, 2-sequence, crossover study, 110 patients were randomly given a 4-mg dose of either the test or reference blonanserin tablet with a 14-day washout period. Blood samples were taken before performing and up to 72 hours following. A validated high-performance liquid chromatography-tandem mass spectrometry technique was used to measure the levels of blonanserin in plasma. Safety was evaluated throughout the study. The study found no significant differences in the maximum observed drug concentration in the plasma (Cmax ), the area under the plasma concentration-time curve from time 0 to the last sampling time (AUC0-t ), and the area under the plasma concentration-time curve from time 0 to infinity (AUC0-∞ ) between the 2 blonanserin formulations. The 90% confidence intervals of the geometric mean ratio of the test/reference formulations for Cmax , AUC0-t , and AUC0-∞ were within the 80%-125% limit. Food dramatically raised blonanserin exposure, and also significantly prolonged the lag time of absorption. No serious adverse events occurred. These results indicate that the 2 blonanserin formulations were bioequivalent and well tolerated in healthy Chinese subjects. In clinical treatment, it is necessary to consider the food effect of blonanserin.

Research and Implementation of Mobile Internet Management Optimization and Intelligent Information System Based on Smart Decision.

The way by which artificial intelligence is implemented is similar to the thinking process of the human brain. People obtain information about external conditions through five senses, namely, vision, hearing, smell, taste, and touch, and, through the further processing of the brain, it forms meaningful decision-making elements. Then, through the process of analysis and reasoning, further decisions are made. In the information age, the application of intelligent management information systems in various fields has promoted the modernization and intelligence of social development. From the perspective of intelligent decision-making, this paper analyzes the requirements of intelligent information systems and designs an intelligent information system based on mobile Internet management optimization, including system management optimization, and proposes an environment-based layer, network transport layer, and the three-tier system architecture of the smart service application layer. Finally, this paper considers the problem of data fusion after system expansion. According to the existing fuzzy fusion algorithm, a weight-based fuzzy fusion algorithm is proposed. The simulation analysis shows that the algorithm can be effectively applied in intelligent information systems.