Red Sindhi cattle in Brazil: population structure and distribution.

The Red Sindhi cattle breed was imported to Brazil in small numbers. Nowadays, the herds of this breed are distributed in the Northeast, Southeast and Midwest regions of the country. In this study, DNA samples of animals originating from 15 herds in the Northeast and Southeast regions have been analyzed to obtain the ancestry proportions, and to gain a better understanding of the current population structure of this breed in Brazil. Samples were genotyped using three different single nucleotide polymorphism (SNP) marker panels. Those markers have been used with the approach of unsupervised hierarchical clustering of individuals, and consequently, the ancestry of the population was divided into six different subpopulations. Three of those ancestry subpopulations were identified to be present in various different herds, while the other three were restricted to only one or two herds each. One of those herds has been kept isolated for more than 30 years, and it was identified to contain two almost exclusive subpopulations. To avoid important losses in the genetic diversity within the Red Sindhi breed in Brazil, we recommend the identification of superior sires from every subpopulation in the establishment of a breeding program for this breed.

HPLC identification of isoniazid residues in bovine milk

The high pressure liquid chromatography (HPLC) was used for the identification of isoniazid (isonicotinic acid hydrazide) in the milk of cattle treated with a dose of 25 mg/kg/day in alternated days. The effect of milk pasteurization on the isoniazid residue concentration was also studied. The drug excretion presented a cyclic variation, with higher levels in the first day after administration (aa), a mean of 1104.48µg/l, and a decrease two days aa, with a mean of 104.12µg/l. Four days after the last administration of the drug it was not possible to identify residues of isoniazid in the milk of treated animals. Body weight and milk yield influenced the amount of the excreted drug, and pasteurization decreased (mean 47.07 per cent) the concentration of isoniazid residue in milk

Idiopathic pulmonary hemosiderosis with cystic lesions: a rare presentation.

This report describes a case of a 49-year-old man with cough, recurrent hemoptysis, and dyspnea during 18 months, presenting with radiological findings of alveolar infiltrate and cystic lesions in left upper lobe. Laboratory studies revealed normocytic hypochromic anemia and normal coagulation tests. C-reactive protein and mucoproteins were negative. Serum protein electrophoresis and complement, urinalysis, serum creatinine, creatinine clearance, and 24-hour urine protein were normal. Tests for antineutrophil cytoplasmic antibodies and anti-glomerular-basement membrane antibodies were negative. Tests for connective tissue diseases were all negative. Histological findings were consistent with those of idiopathic pulmonary hemosiderosis. Radiological findings are discussed.

Psychosexual characteristics of male university students in Brazil.

Male freshmen (N = 268) at the State University of Campinas (UNICAMP) in the state of Sao Paulo in Brazil responded to a questionnaire concerning aspects of their sexuality from the onset of adolescence. Topics such as physical changes, first ejaculation, masturbation, homosexual manifestations, and sexual practices were investigated, as well as present attitudes toward virginity, intercourse, birth control, abortion, and prevention of AIDS. The quality of the relationship established with parents and the possibilities for dialogue about sex in the family circle were also surveyed. The majority of the subjects revealed satisfactory development in most areas of their sexuality, as well as a good relationship with their parents. Nevertheless, great difficulty was found in dialogue about sex within the family circle. Of these young men, 32% were still virgins at the end of their freshman year, but a considerable number of those already sexually active reported behavior which was inappropriate for the prevention of pregnancy and AIDS. The results are analyzed using psychoanalytic theories of psychosexual development.

PIP: A random sample of 268 male freshmen of mean age 19.6 years at the State University of Campinas in the state of Sao Paulo, Brazil, responded to a questionnaire in 1990 on aspects of their sexuality from the beginning of their adolescence. Topics such as physical changes, first ejaculation, masturbation, homosexual manifestations, and sexual practices were investigated, as well as present attitudes toward virginity, intercourse, birth control, abortion, and AIDS prevention. The quality of their relationships with parents was also surveyed. The sample comprised 31% of the entering students for that year. 32% were living with their parents. Most respondents reported satisfactory development in most areas of their sexuality, as well as a good relationship with their parents. However, they found it very difficult to discuss sex within their family circles. 32% were still virgins at the end of their freshman year. 28% and 20% had homosexual manifestations during childhood/early adolescence and currently, respectively, including fantasies, attraction to men/boys, physical contact with men/boys, and sexual intercourse with men/boys. 38% of the sexually active men reported taking no measures to prevent pregnancy and HIV transmission.

Psychosexual characteristics of female university students in Brazil.

Freshmen women (N = 240) at the State University of Campinas (UNICAMP) in the state of Sao Paulo, Brazil responded to a questionnaire concerning several aspects of their sexuality from the beginning of adolescence. Topics such as body changes during puberty, menarche, menstruation, masturbation, sexual identity, virginity, sexual relations, maternity, contraceptives, abortion, and attitudes toward AIDS were investigated, as well as the level and sources of information about sex and the quality of the subjects' relationships with their parents. The majority of the subjects revealed satisfactory development in most of the aspects surveyed, as well as in their relationships with their parents except where sexual issues were concerned. Nevertheless, most of the students reported menstrual disturbances, and a significant number of the sexually active reported inappropriate behavior in relation to contraception and AIDS prevention. The results of the research are analyzed using psychodynamic theories of sexual development.

PIP: A survey of 240 randomly selected female students (average age, 19.9 years) at the State University of Campinas in Sao Paulo, Brazil, provided comprehensive information about the physical, psychological, and psychosexual dimensions of adolescence. Over half reported negative feelings or indifference to body changes associated with puberty and 54% stated they did not receive information on sexual development from their parents. The average age at menarche was 12.3 years. 79% reported persistent menstruation-related discomfort (e.g., cramps, moodiness). Virginity until marriage was considered essential by 14%; to 42%, it made no difference in the context of a loving relationship. 44% of female students had experienced intercourse; the average age at initiation of sexual relations was 17.6 years. 78% stated the idea of having a child was fundamental or agreeable. 84% of sexually active students were using contraception (including unreliable methods such as rhythm). Although 65% viewed abortion as a theoretically acceptable option, only 8% indicated they would make this choice and just 6% had had an abortion. 6% of students considered themselves at risk of AIDS. Most students characterized their relationship with their parents as good, yet they preferred to talk to friends or siblings about sexual matters. Although these students appear to have satisfactorily negotiated most of the developmental tasks of adolescence, there was some evidence of failure to resolve independence-dependence conflicts.

[Study of morbidity in patients hospitalized at the Clinic Hospital at the Medical School of the USP-1989]. / Estudo da morbidade dos pacientes internados no Hospital das Clínicas da Faculdade de Medicina da USP-1989.

The diagnostic categories of the patients discharged from the "Hospital das Clínicas" of the University of São Paulo in 1989 were arranged according the International Classification of Diseases (I.C.D.) and analysed. In each Group sex, age and the reason of discharge or death was indicated. The data concerning 39,601 cases were provided by the Medical Data Service of the "Instituto Central" of the "Hospital das Clínicas". Only the principal diagnosis was taken into account. In the "Instituto de Psiquiatria" most the patients (55.4%) were males between 20 and 49 years of age. The main diagnostic categories were affective psychoses (20.3%), schizophrenic disorders (15%), and disorders related to alcoholism (9.5%). The mortality rate was 0.27%. In the "Instituto da Criança" 56% of the patients that left the hospital were male children and 45.8% of them were less than one year old. Regarding to the diagnostic categories the most important one was that of the diseases of the respiratory system with 27.1% of cases, followed by that of infectious and parasitic diseases with 16.0% of cases. Within the respiratory diseases the most important were the pneumonias caused by not specified microorganisms, and within the infectious diseases the most important was the diarrhea of presumably infectious origin. The mortality rate in this Institute was 9.4%. The "Instituto de Ortopedia e Traumatologia" left 3,825 patients 61.7% males, and 46.9% of them were aged between 20 and 49 years. The greatest number of cases (57.1%) belonged to the Chapter "Injury and Poisoning" followed by that of "Diseases of the Muscoleskeletal System" and Connective Tissue Diseases (23.5%). In this Institute the mortality rate was 1.2%. From the "Instituto do Coração" 7,194 patients were discharged; 65% of them were males, varying their age between 50 and 69 years. The diseases of the circulatory system were mostly ischemic heart disease, miocardiopathies and rheumatic heart diseases. Mortality rate in this Institute was 10.8%. The "Instituto Central" was responsible for 65.6% of all the patients discharged from the "Hospital das Clínicas" (26,015 cases). As to the diagnostic categories the predominant chapter was that of "Injury and Poisoning" (12.8% of cases) followed by the "Diseases of the Digestive System" (10.9%) "Neoplasms" (10.8%) and the "Diseases of Circulatory System" (9.2%). The mortality rate in the "Instituto Central" was 7.2%.

[Epidemiology of tetanus in São Paulo State (Brazil)]. / Aspectos epidemiológicos do tétano no Estado de São Paulo (Brasil).

Tetanus is a reportable disease in the State of São Paulo since 1978. The data from this source show a trend toward a decrease in the incidence of tetanus, although it is still higher than in the developed countries. There is a constantly high mortality rate. We have studied 133 cases of non-neonatal tetanus that had been reported to the Epidemiology Surveillance Center of the State of São Paulo in 1989. The data we analysed were obtained from the epidemiological report form routinely used during the investigation and confirmation of the cases. The incidence was 0.41 per 100.000 population and the mortality rate was 44.36%. It was possible to identify some groups under a higher risk like old-aged, those living in the western and north-western regions of the State and those classified occupationally as "domestic activities", "rural workers" and "pensioners". We propose that these groups deserve special attention, together with pregnant women and children. In 18.3% of the cases the incubation period could not be determined. The peak incidence occurred in May. We also compared the mortality rate in the group of patients in the Hospital das Clínicas da FMUSP (the only hospital in the State of São Paulo with an Intensive Unit Care designed exclusively to the treatment of the patients with tetanus) and the group of patients that were admitted to other hospitals. The mortality rate in the HC-FMUSP was 34.5% and in the other hospitals was 49.5%, but this was not statistically significant. The role of the medical facilities in the prognosis of the patient with tetanus specially the importance of considering at the same time the severity of the disease and the characteristics of the therapy deserve further study in order to contribute to the development of the medical assistance to the patients with tetanus.

Energy costs of flowering, fruiting, and cherelle wilt in cacao.

Groups of 14-year-old cacao (Theobroma cacao L.) trees were hand pollinated, pollinated naturally or had their fruits continuously removed. Wilted and non-wilted cherelles (small fruits) were counted every 2 weeks, fallen flowers were counted weekly and mature pods were harvested monthly from 1983 through 1986. Carbohydrate, lipid and protein contents of wilted cherelles, mature pods and flowers were determined. Continuous removal of fruits caused a constant initiation of flowers and a significant increase in flowering intensity compared with the other treatments. The quantity of cherelles in the hand-pollinated trees was significantly greater than in the naturally pollinated trees. However, the number of mature fruits in both treatments was not statistically different because of increased cherelle wilting in the hand-pollinated trees. The continuously depodded trees allocated approximately 8 and 5 times more assimilate to flower production than the hand- and naturally pollinated trees, respectively. The naturally pollinated trees used only about one third as much energy for the production of flowers and wilted cherelles as the hand-pollinated trees, but about 1.4 times more energy than the depodded trees. It is concluded that fruit set in cacao is regulated by assimilate production and that cherelle wilting is the mechanism whereby the tree adjusts production.

Tratamento da ancilostomiase, ascaridiase e tricocefaliase por meio do albendazol ou do mebendazol. / Treatment of ancylostomiasis, ascaridiasis and trichocephaliasis with albendazole or mebendazole

Por meio do albendazol (dose unica de 400 mg) ou do mebendazol) (100 mg, duas vezes em 24 horas, durante tres dias), foram tratados individuos com ancilostomiase, ascaridiase e tricocefaliase ou com, pelo menos, duas dessas verminoses. As porcentagens de curas verificadas correponderam, respectivamente, a 55,2%, 91,2% e 38,5% e a 44,0%, 90,0% e 71,4% no que concerne as parasitoses e aos medicamentos citados. O albendazol e composto cuja atividade antihelmintica, em seres humanos, vem sendo avaliada ultimamente e o mebendazol, ja empregado de forma ampla, serviu, no estudo realizado, como termo de comparacao. Os remedios em apreco nao causaram disturbios colaterais dignos de registro, tendo ficado patente que o albendazol, administravel de maneira bastante singela, desenvolveu atividade curativa semelhante a do mebendazol no que diz respeito a ancilostomiase e a ascaridiase. A proposito da investigacao efetuada, sucedeu analise estatistica dos resultados obtidos

Aspectos do processo de identificacao na adolescencia: um estudo realizado em escolas de 2o. grau em Campinas. / Aspects of identification process in adolescence: study performed in 2nd grade schools in Campinas

115 adolescentes entre 15 e 18 anos, de ambos os sexos, residentes em Campinas e frequentando escolas de 2o. grau foram entrevistados, revelando as seguintes tendencias: 1) um nivel de dependencia familiar mais elevado do que o esperado para a faixa de idade; 2) uma repressao sexual acentuada quando comparada a outros grupos de mesma idade, relatados na literatura; e relacionado a esses dados uma dificuldade de aceitacao das mudancas corporais dessa fase, indicada pela analise do teste projetivo da figura humana; 3) por ultimo, a indicacao de uma pratica bastante difundida do uso de drogas, no grupo entrevistado, obtida atraves de respostas bem projetivas