RESUMO
Phylloquinone (vitamin K1; 2-methyl-3-phytyl-1,4-naphthoquinone), the secondary electron acceptor A1 in photosystem I of plants, algae, and cyanobacteria, mediates the electron transfer between A0 (a monomeric chlorophyll a) and the iron-sulfur cluster Fx. In order to investigate the interaction of vitamin K1 with the A1-binding site, their models on the non-covalent complexes were obtained and studied. The fluorescent properties of vitamin K1, its derivatives, and their complexes with Trp showed a possible role of amino acid components in the formation of a stable energy state, which provides the energy redistribution between oxidized and reduced forms of vitamin K1. The formation of the charge-transfer complex and the influence of the ratio of the components on fluorescence derived from the tryptophan-vitamin K1, tryptophan-dihydrovitamin K1 , tryptophan-quinhydrone K1, and tryptophan-naphthochromanol complexes are described. The data obtained allow us to suggest that naphthochromanol is involved in the energy transfer reaction in PS I as an intermediate form of the secondary electron acceptor.
Assuntos
Complexo de Proteína do Fotossistema I/química , Plantas/metabolismo , Triptofano/química , Vitamina K 1/química , Sequência de Aminoácidos , Sítios de Ligação , Transporte de Elétrons , Modelos Moleculares , Dados de Sequência Molecular , Espectrometria de FluorescênciaRESUMO
The article shows the urgency of the problem of treatment of genu varus deformity consequent upon Stage III arthrosis deformans; nonoperative treatment of this contingent of patients was ineffective. The authors show the results of an operative method for valgoid osteotomy conducted in 52 cases; the patients' ages ranged from 42 to 78 years. The work discusses the clinical picture, techniques, and postoperative management of the patients. The late-term results were studied in follow-up periods of up to 7 years. The results were good in 92% and satisfactory in 8% of patients.
