RESUMO
In the article the results of clinical researches of efficiency of preparation of Cocarnit are resulted for patients after endoprosthesis of large joints. It is routine that for patients, receiving preparation of Cocarnit after the operation period there was a decline in the amount of complaints of patients on the total somatical state. Preparation of Ccocarnit was positively estimated outside patients, meaningful by-reactions, serving reason of abolition of preparation, was not marked. At the reception preparation of Cocarnit greater part of investigational laboratory indexes (table of contents of glucose, ß-lipoproteines, total chondroitisulfates, TBC-productes (malonic dyaldehyde), activity of aspartataminotransferase, alkaline phosphatase and ß-glutamyltranspeptidase), the indexes of clinical blood test and leucocytar indexes during a supervision did not have reliable differences from such as the persons of the control group, that confirms good bearab leness of the indicated preparation. Application preparation of Cocarnit for patients in composition the chart of treatment of patients after endoprosthesis of large joints brought maintenance over of cholesterol to the decline, glycoproteins, TBC-products (malonic dyaldehyde), activity of alaninaminotransferase, that specifies on normalizing influence of the indicated preparation in relation to the basic types of exchange of matters.
Assuntos
Artroplastia de Quadril/reabilitação , Artroplastia do Joelho/reabilitação , Articulação do Quadril/efeitos dos fármacos , Articulação do Joelho/efeitos dos fármacos , Substâncias Protetoras/uso terapêutico , Trifosfato de Adenosina/uso terapêutico , Adulto , Idoso , Fosfatase Alcalina/sangue , Aspartato Aminotransferases/sangue , Glicemia/metabolismo , Sulfatos de Condroitina/sangue , Combinação de Medicamentos , Feminino , Articulação do Quadril/metabolismo , Articulação do Quadril/patologia , Articulação do Quadril/cirurgia , Humanos , Articulação do Joelho/metabolismo , Articulação do Joelho/patologia , Articulação do Joelho/cirurgia , Lipoproteínas LDL/sangue , Masculino , Malondialdeído/sangue , Pessoa de Meia-Idade , Niacinamida/uso terapêutico , Estresse Oxidativo/efeitos dos fármacos , Satisfação do Paciente , Qualidade de Vida , Tiamina Pirofosfato/uso terapêutico , Vitamina B 12/uso terapêutico , gama-Glutamiltransferase/sangueRESUMO
Chronic stress promoted disintegration of collagen and non-collagen proteins in the periodontal bone tissue, which depended on typological characteristics of animals. Stress-predisposed animals were characterized by most pronounced disturbances.
Assuntos
Matriz Óssea/química , Osso e Ossos/anatomia & histologia , Periodonto/anatomia & histologia , Estresse Psicológico , Animais , Matriz Óssea/metabolismo , Osso e Ossos/metabolismo , Hexosaminas/metabolismo , Hidroxiprolina/metabolismo , Masculino , Mandíbula/anatomia & histologia , Periodonto/metabolismo , Ratos , Ratos Wistar , Tirosina/metabolismoAssuntos
Anti-Inflamatórios não Esteroides/uso terapêutico , Osteoartrite do Quadril/tratamento farmacológico , Corticosteroides/uso terapêutico , Adulto , Terapia Combinada , Humanos , Pessoa de Meia-Idade , Osteoartrite do Quadril/cirurgia , Cuidados Pré-Operatórios , Antagonistas de Prostaglandina/uso terapêuticoAssuntos
Fraturas Ósseas/tratamento farmacológico , Quimiólise do Disco Intervertebral , Papaína/uso terapêutico , Traumatismos da Coluna Vertebral/tratamento farmacológico , Animais , Modelos Animais de Doenças , Avaliação Pré-Clínica de Medicamentos , Fraturas Ósseas/sangue , Fraturas Ósseas/patologia , Necrose/patologia , Coelhos , Traumatismos da Coluna Vertebral/sangue , Traumatismos da Coluna Vertebral/patologia , Coluna Vertebral/efeitos dos fármacos , Coluna Vertebral/patologia , Fatores de Tempo , Cicatrização/efeitos dos fármacosRESUMO
The authors have made an analysis of unsatisfactory remote results in 83 (21.5%) out of 387 patients operated for endoprosthezing of the hip joint which resulted from shaking loose the endoprostheses in the bone tissue. A conclusion is made that the following factors may be considered as contraindications to endoprosthesis of the hip joints: coxarthrosis against the background of arthroso-arthritis, neglected stages of protrusive coxarthrites, deforming osteoarthrosis due to the use of corticosteroids, pronounced senile osteoporosis.
