Comparison of lead levels in human permanent teeth from Strasbourg, Mexico City, and rural zones of Alsace.

A comparative study of the mean lead concentrations in enamel and dentin of human premolars and permanent molars was conducted by means of a systematic sampling procedure with energy-dispersive x-ray fluorescence analysis. In a first series of analyses, no significant statistical differences in mean lead concentrations at various levels of enamel and dentin were noted between young patients of Strasbourg and those of small villages of Alsace, nor between elderly patients living in these two locations, despite the fact that motor traffic was significantly lower in the rural zones. However, in both locations, a significantly higher concentration of lead was observed in enamel and dentin in relation to age. In a second series of analyses, the mean lead concentrations of both dental hard tissues of premolars and permanent molars of young individuals from Strasbourg, rural Alsace, and Mexico City were compared. Significantly higher mean lead concentrations were found in enamel and dentin samples from Mexico City. This was most evident for inner coronal dentin (5.7 and 6.1 times greater than in teeth of Strasbourg and rural zones of Alsace, respectively) and for pulpal root dentin (6.9 and 8.9 times greater than in teeth of Strasbourg and rural zones of Alsace). It is proposed that the higher lead concentrations are related to the higher lead content of motor gasoline and to more intense traffic conditions. The dental hard tissues appear to be of value for the study of environmental lead pollution.

[Mechanism of anemia seen in children living in the Amazon forest of Peru]. / Mécanisme de l'anémie observée chez les enfants vivant dans la forêt amazonienne du Pérou.

A recent study performed in 48 indian children (ranging to 2 to 10 years) from Peruvian Amazona emphasizes the high incidence of sideropenia as a mechanism of anemia. Indeed neither proteins loss or hemolysis was found in these patients. Sideropenia was secondary to iron loss closely related to parasitosis. Thus it could be hopeful to improve both quality of nutrition and life of such patients as well as treatment of parasitosis.

Lack of antibody induction by Histolyn-CYL, a new skin-testing reagent for histoplasmosis.

Histolyn-CYL, a yeast phase skin-test reagent, was administered to 85 histoplasmin-sensitive subjects living in the United States and South America. In a multicenter study, sera were obtained at the time the skin tests were read and again 3 weeks later. In no instance did the skin test induce significant complement-fixing antibody changes or antibodies detected by immuno-diffusion.