[Acute non-allergic reaction after administration of penicillin as a factor in the occurrence of neurotic symptoms]. / Ostra niealergiczna reakcja po penicylinie jako czynnik wyzwalajacy zespoly nerwicowe.

The effect of a acute non-allergic reaction occurring after injection of procaine penicillin on the occurrence of different neurotic symptoms is a subject of the paper. 31 clinical cases, in which during the penicillin treatment the said reaction took place, were analysed. It has been found that the most often found consequence of that treatment is conversive neurosis, and subsequently the hypochondriac syndrome. On an average an acute non-allergic reaction occurred after the sixth injection. In 94% of the patients the neurotic symptoms appeared immediately after the described reaction. A positive correlation between the patient's age and an intensity of the converse symptoms was found. The Hoigne'a syndrome was a strong mental trauma, and was treated as an allergic shock for all of the patients. The patients were afraid of the next injection and they all refused to give permission for the continuation of such treatment. Neurotic syndromes related to Hoigne's syndrome turned out to be prolonged with a tendency for relapses, and low susceptibility to different methods of treatment. The mechanism of non-allergic acute reaction after procaine penicillin and ways of its prevention are also discussed.

Effect of changes in lung volume on respiratory system compliance in newborn infants.

Total respiratory system compliance (Crs) at volumes above the tidal volume (VT) was studied by use of the expiratory volume clamping (EVC) technique in 10 healthy sleeping unsedated newborn infants. Flow was measured with a pneumotachograph attached to a face mask and integrated to yield volume. Volume changes were confirmed by respiratory inductance plethysmography. Crs measured by EVC was compared with Crs during tidal breathing determined by the passive flow-volume (PFV) technique. Volume increases of approximately 75% VT were achieved with three to eight inspiratory efforts during expiratory occlusions. Crs above VT was consistently greater than during tidal breathing (P less than 0.0005). This increase in Crs likely reflects recruitment of lung units that are closed or atelectatic in the VT range. Within the VT range, Crs measured by PFV was compared with that obtained by the multiple-occlusion method (MO). PFV yielded greater values of Crs than MO (P less than 0.01). This may be due to braking of expiratory airflow after the release of an occlusion or nonlinearity of Crs. Thus both volume recruitment and airflow retardation may affect the measurement of Crs in unsedated newborn infants.

[Follow-up evaluation of the results of the treatment of 40 cases of anxiety neurosis]. / Katamnestyczna ocena wyników leczenia 40 przypadków nerwicy lekowej.

The follow-up study lasting 2 to 7 years of 40 patients with diagnosis of anxiety neurosis hospitalized in the Department of Psychiatry, Medical Academy Gdansk, was performed. Only in 9 cases "pure" neurosis was observed. In the majority of cases neurosis was accompanied by histrionic traits. The possibility of organic brain damage was raised in 7 cases. No symptoms of anxiety were found in 14 cases during the follow-up period, while in 15 cases substantial decrease of anxiety symptoms was found, and in 11 cases anxiety symptoms relapsed. The dependence between therapeutic results and time of duration of symptoms was noted. Direct results of treatment did not differ significantly from those found in follow-up studies.