1.
J Org Chem
; 83(6): 3265-3274, 2018 03 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29484888
RESUMO
Facile synthesis of 5-fluoropyrazoles by direct fluorination of pyrazoles with N-fluorobenzenesulfonimide (NFSI) was elaborated. This approach was used to prepare the unsubstituted 5-fluoro-1 H-pyrazole, the known fungicide Penflufen, and many functionalized 5-fluoropyrazoles: building blocks for medicinal chemistry and agrochemistry.