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Genetika ; 24(12): 2141-8, 1988 Dec.
Artigo em Russo | MEDLINE | ID: mdl-3150756

RESUMO

The genetic effect of some factors is generally evaluated as an average response of all individuals, without taking into account their potential differences. The presence of individual sensitivity in separate Drosophila organisms to the mutagenic influence of ethyl methanesulfonate was shown when analysing recessive sex-linked lethal mutations in germ cells of males. Different sensitivity of separate individuals to mutagens reflects the existence of cryptic genetic variability in Drosophila strains on a large scale. It is advisable to take into account individual sensitivity of organisms to mutagenic factors, when conducting mutation research and studying genetic consequences of biosphere pollution.


Assuntos
Drosophila melanogaster/genética , Metanossulfonato de Etila/toxicidade , Mutagênicos , Animais , Relação Dose-Resposta a Droga , Genes Letais/efeitos dos fármacos , Células Germinativas/efeitos dos fármacos , Masculino
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