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Gig Sanit ; (10): 28-30, 1990 Oct.
Artigo em Russo | MEDLINE | ID: mdl-2074021

RESUMO

Fungicide tecto (thiabendazol) is a low-toxic compound, produces a weak skin-resorptive and local irritating effect. Cumulation coefficient is 3.96. Threshold and subthreshold doses for tecto were determined as a result of 12-months chronic experiment on white rats--3.7 and 0.37 mg/kg, respectively. The allowable 24-hours dose for human exposure to the chemical is 0.6 mg. The threshold tecto concentration according to the effect on the general sanitary regimen of water reservoirs appeared to be 1 mg/l. According to the limiting toxicological index 0.05 mg/l was recommended as tecto MAC for the water of reservoirs.


Assuntos
Fungicidas Industriais/toxicidade , Tiabendazol/toxicidade , Poluentes Químicos da Água/toxicidade , Animais , Relação Dose-Resposta a Droga , Feminino , Fungicidas Industriais/farmacocinética , Fungicidas Industriais/farmacologia , Dose Letal Mediana , Masculino , Concentração Máxima Permitida , Coelhos , Ratos , Tiabendazol/farmacocinética , Tiabendazol/farmacologia , Poluentes Químicos da Água/farmacocinética , Poluentes Químicos da Água/farmacologia
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