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1.
Can Rev Sociol ; 60(4): 668-685, 2023 11.
Artigo em Inglês | MEDLINE | ID: mdl-37661315

RESUMO

Using US National Education Longitudinal Study (NELS) data, we explore how parental education and primary students' perceptions of their teachers interact to impact students' self-efficacy in mathematics. Our results demonstrate that students tend to have higher self-efficacy if they perceive that their teacher promotes the importance of mathematics. This relationship holds regardless of parental education, though it is strongest for children of parents without a university education. Children of less educated parents also tend to have lower self-efficacy if they attend private schools, which typically have high average parental socio-economic status (SES). School type has no discernable impact on children of university-educated parents. These findings are highly relevant to the Canadian context, which is characterized by schools being stratified by SES and the high importance of STEM education for occupational outcomes.


En utilisant les données de l'étude longitudinale de l'éducation nationale américaine, nous explorons comment l'éducation parentale et les perceptions qu'ont les élèves du primaire de leurs enseignants interagissent pour influencer l'auto-efficacité des élèves en mathématiques. Nos résultats démontrent que les élèves ont tendance à avoir une plus grande efficacité personnelle s'ils perçoivent que leur enseignant promeut l'importance des mathématiques. Cette relation est valable quel que soit le niveau d'éducation des parents, bien qu'elle soit plus forte pour les enfants dont les parents n'ont pas fait d'études universitaires. Les enfants de parents moins éduqués ont également tendance à avoir une moins bonne auto-efficacité s'ils fréquentent des écoles privées, où le statut socio-économique moyen des parents est généralement élevé. Le type d'école n'a pas d'impact perceptible sur les enfants dont les parents ont fait des études universitaires. Ces résultats sont très pertinents dans le contexte canadien, qui se caractérise par une stratification des écoles en fonction du statut socio-économique et une grande importance de l'enseignement des STIM pour les résultats professionnels.


Assuntos
Professores Escolares , Instituições Acadêmicas , Criança , Humanos , Estudos Longitudinais , Canadá , Escolaridade , Matemática , Pais
2.
Neuron ; 107(5): 954-971.e9, 2020 09 09.
Artigo em Inglês | MEDLINE | ID: mdl-32589878

RESUMO

Adaptive movements are critical for animal survival. To guide future actions, the brain monitors various outcomes, including achievement of movement and appetitive goals. The nature of these outcome signals and their neuronal and network realization in the motor cortex (M1), which directs skilled movements, is largely unknown. Using a dexterity task, calcium imaging, optogenetic perturbations, and behavioral manipulations, we studied outcome signals in the murine forelimb M1. We found two populations of layer 2-3 neurons, termed success- and failure-related neurons, that develop with training, and report end results of trials. In these neurons, prolonged responses were recorded after success or failure trials independent of reward and kinematics. In addition, the initial state of layer 5 pyramidal tract neurons contained a memory trace of the previous trial's outcome. Intertrial cortical activity was needed to learn new task requirements. These M1 layer-specific performance outcome signals may support reinforcement motor learning of skilled behavior.


Assuntos
Aprendizagem/fisiologia , Córtex Motor/citologia , Córtex Motor/fisiologia , Destreza Motora/fisiologia , Células Piramidais/citologia , Células Piramidais/fisiologia , Animais , Masculino , Camundongos , Camundongos Endogâmicos C57BL
3.
Nat Commun ; 10(1): 4214, 2019 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-31527635

RESUMO

Opto-mechanical interactions in planar photonic integrated circuits draw great interest in basic research and applications. However, opto-mechanics is practically absent in the most technologically significant photonics platform: silicon on insulator. Previous demonstrations required the under-etching and suspension of silicon structures. Here we present surface acoustic wave-photonic devices in silicon on insulator, up to 8 GHz frequency. Surface waves are launched through absorption of modulated pump light in metallic gratings and thermo-elastic expansion. The surface waves are detected through photo-elastic modulation of an optical probe in standard race-track resonators. Devices do not involve piezo-electric actuation, suspension of waveguides or hybrid material integration. Wavelength conversion of incident microwave signals and acoustic true time delays up to 40 ns are demonstrated on-chip. Lastly, discrete-time microwave-photonic filters with up to six taps and 20 MHz-wide passbands are realized using acoustic delays. The concept is suitable for integrated microwave-photonics signal processing.

4.
Tissue Eng Part A ; 23(9-10): 403-414, 2017 05.
Artigo em Inglês | MEDLINE | ID: mdl-28437179

RESUMO

Recent studies in the field of neuro-tissue engineering have demonstrated the promising effects of aligned contact guidance cue to scaffolds of enhancement and direction of neuronal growth. In vivo, neurons grow and develop neurites in a complex three-dimensional (3D) extracellular matrix (ECM) surrounding. Studies have utilized hydrogel scaffolds derived from ECM molecules to better simulate natural growth. While many efforts have been made to control neuronal growth on 2D surfaces, the development of 3D scaffolds with an elaborate oriented topography to direct neuronal growth still remains a challenge. In this study, we designed a method for growing neurons in an aligned and oriented 3D collagen hydrogel. We aligned collagen fibers by inducing controlled uniaxial strain on gels. To examine the collagen hydrogel as a suitable scaffold for neuronal growth, we evaluated the physical properties of the hydrogel and measured collagen fiber properties. By combining the neuronal culture in 3D collagen hydrogels with strain-induced alignment, we were able to direct neuronal growth in the direction of the aligned collagen matrix. Quantitative evaluation of neurite extension and directionality within aligned gels was performed. The analysis showed neurite growth aligned with collagen matrix orientation, while maintaining the advantageous 3D growth.


Assuntos
Colágeno/química , Hirudo medicinalis/citologia , Hidrogéis/química , Neuritos/metabolismo , Animais
5.
J Biol Chem ; 291(41): 21434-21447, 2016 Oct 07.
Artigo em Inglês | MEDLINE | ID: mdl-27551039

RESUMO

Apiose is a branched monosaccharide that is present in the cell wall pectic polysaccharides rhamnogalacturonan II and apiogalacturonan and in numerous plant secondary metabolites. These apiose-containing glycans are synthesized using UDP-apiose as the donor. UDP-apiose (UDP-Api) together with UDP-xylose is formed from UDP-glucuronic acid (UDP-GlcA) by UDP-Api synthase (UAS). It was hypothesized that the ability to form Api distinguishes vascular plants from the avascular plants and green algae. UAS from several dicotyledonous plants has been characterized; however, it is not known if avascular plants or green algae produce this enzyme. Here we report the identification and functional characterization of UAS homologs from avascular plants (mosses, liverwort, and hornwort), from streptophyte green algae, and from a monocot (duckweed). The recombinant UAS homologs all form UDP-Api from UDP-glucuronic acid albeit in different amounts. Apiose was detected in aqueous methanolic extracts of these plants. Apiose was detected in duckweed cell walls but not in the walls of the avascular plants and algae. Overexpressing duckweed UAS in the moss Physcomitrella patens led to an increase in the amounts of aqueous methanol-acetonitrile-soluble apiose but did not result in discernible amounts of cell wall-associated apiose. Thus, bryophytes and algae likely lack the glycosyltransferase machinery required to synthesize apiose-containing cell wall glycans. Nevertheless, these plants may have the ability to form apiosylated secondary metabolites. Our data are the first to provide evidence that the ability to form apiose existed prior to the appearance of rhamnogalacturonan II and apiogalacturonan and provide new insights into the evolution of apiose-containing glycans.


Assuntos
Bryopsida/metabolismo , Carboxiliases/metabolismo , Clorófitas/metabolismo , Evolução Molecular , Proteínas de Plantas/metabolismo , Açúcares de Uridina Difosfato/biossíntese , Bryopsida/genética , Carboxiliases/genética , Parede Celular/genética , Parede Celular/metabolismo , Clorófitas/genética , Proteínas de Plantas/genética , Polissacarídeos/biossíntese , Polissacarídeos/genética , Açúcares de Uridina Difosfato/genética
6.
Opt Lett ; 37(24): 5112-4, 2012 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-23258022

RESUMO

Stimulated Brillouin scattering (SBS) amplification is obtained in directly written As2S3 channel waveguides. Centimeter-long waveguides were written using a Ti:sapphire femtosecond laser, operating at a central wavelength of 810 nm. The cross-section of the waveguides was of 4 µm×1 µm. A Brillouin frequency shift of 7.5 GHz is observed, in general agreement with corresponding previous studies. The SBS gain spectrum in the short waveguides is comparatively broad, with a full width at half-maximum of 200 MHz. We attribute the broad linewidth to the spatial evolution of the electromagnetic field profile along the waveguide.

7.
J Magn Reson ; 167(2): 317-21, 2004 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15040988

RESUMO

We present an angle dependent nuclear quadrupole resonance (ADNQR) method to determine the electric field gradient asymmetry parameter eta in systems where the resonance line is so broad that the radio frequency field can excite only a portion of the nuclear spins. In this situation, the recently developed spectroscopic methods are not applicable. ADNQR is useful for single crystals and oriented powders, and, for small eta determines eta4. Therefore, it can be used to evaluate fluctuations in eta due to inhomogeneities. We demonstrate the application of ADNQR experimentally to oriented superconducting YBa2Cu3O7 powder.

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