Roadmap for Optical Metasurfaces.

Metasurfaces have recently risen to prominence in optical research, providing unique functionalities that can be used for imaging, beam forming, holography, polarimetry, and many more, while keeping device dimensions small. Despite the fact that a vast range of basic metasurface designs has already been thoroughly studied in the literature, the number of metasurface-related papers is still growing at a rapid pace, as metasurface research is now spreading to adjacent fields, including computational imaging, augmented and virtual reality, automotive, display, biosensing, nonlinear, quantum and topological optics, optical computing, and more. At the same time, the ability of metasurfaces to perform optical functions in much more compact optical systems has triggered strong and constantly growing interest from various industries that greatly benefit from the availability of miniaturized, highly functional, and efficient optical components that can be integrated in optoelectronic systems at low cost. This creates a truly unique opportunity for the field of metasurfaces to make both a scientific and an industrial impact. The goal of this Roadmap is to mark this "golden age" of metasurface research and define future directions to encourage scientists and engineers to drive research and development in the field of metasurfaces toward both scientific excellence and broad industrial adoption.

High-Q and high finesse silicon microring resonator.

We demonstrate the design, fabrication, and experimental characterization of a single transverse mode adiabatic microring resonator (MRR) implemented using the silicon-on- insulator (SOI) platform using local oxidation of silicon (LOCOS) approach. Following its fabrication, the device was characterized experimentally and an ultrahigh intrinsic Q-factor of ∼2 million with a free spectral range (FSR) of 2 nm was achieved, giving rise to a finesse of ∼1100, the highest demonstrated so far in SOI platform at the telecom band. We have further studied our device to analyze the source of losses that occur in the MRR and to understand the limits of the achievable Q-factor. The surface roughness was quantified using AFM scans and the root mean square roughness was found to be ∼ 0.32±0.03 nm. The nonlinear losses were further examined by coupling different optical power levels into the MRR. Indeed, we could observe that the nonlinear losses become more pronounced at power levels in the range of hundreds of microwatts. The demonstrated approach for constructing high-Q and high finesse MRRs can play a major role in the implementation of devices such as modulators, sensors, filters, frequency combs and devices that are used for quantum applications, e.g., photon pair generation.

Exploiting Zone-Folding Induced Quasi-Bound Modes to Achieve Highly Coherent Thermal Emissions.

Thermal emissions with high coherence, although not as high as those of lasers, still play a crucial role in many practical applications. In this work, by exploiting the geometric perturbation-induced optical lattice tripling and the associated Brillion zone folding effect, we propose and investigate thermal emissions in the mid-infrared with simultaneous high temporal and spatial coherence. In contrast with the case of period-doubling perturbation in our previous work, the steeper part of the guided mode dispersion band will be folded to the high-symmetry Γ point in the ternary grating. In this case, a specific emission wavelength corresponds to only a very small range of wavevectors. Consequently, apart from the high temporal coherence characterized by an experimental bandwidth around 30 nm, the achieved thermal emissions also feature ultrahigh spatial coherence. Calculations show that at the thermal emission wavelengths in the mid-infrared, the spatial coherence length can easily reach up to mm scale.

Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders.

Modern research data suggest a therapeutic role for serotonergic psychedelics in depression and other neuropsychiatric disorders, although psychotomimetic effects may limit their widespread utilization. Serotonergic psychedelics enhance neuroplasticity via serotonin 2 A receptors (5HT2AR) activation and complex serotonergic-glutamatergic interactions involving the ionotropic glutamate receptors, tropomyosin receptor kinase B (TrkB) and the mammalian target of rapamycin (mTOR). N-methyl-d-aspartate receptors (NMDAR) channel antagonists, i.e. ketamine, and glycine modulatory site full and partial agonists, i.e., D-serine (DSR) and D-cycloserine (DCS), share some of these mechanisms of action and have neuroplastic and antidepressant effects. Moreover, procognitive effects have been reported for DSR and DCS and 5HT2AR-NMDAR interactions modulate neuronal excitability in prefrontal cortex and represent a target for new antipsychotics. We hypothesize that the synchronous administration of a psychedelic and a NMDAR modulator may increase the therapeutic impact of each of the treatment components and allow for dose adjustments and improved safety. We propose to initially focus research on the acute concurrent administration of psilocybin and DSR or DCS in depression.

Simulation of laser-induced tunnel ionization based on a curved waveguide.

The problem of tunneling ionization and the associated questions of how long it takes for an electron to tunnel through the barrier, and what the tunneling rate has fascinated scientists for almost a century. In strong field physics, tunnel ionization plays an important role, and accurate knowledge of the time-dependent tunnel rate is of paramount importance. The Keldysh theory and other more advanced related theories are often used, but their accuracy is still controversial. In previous work, we suggested using a curved waveguide as a quantum simulator to simulate the tunnel ionization process. Here we implemented for the first time such a curved waveguide and observed the simulated tunneling ionization process. We compare our results with the theory.

CMOS-compatible electro-optical SRAM cavity device based on negative differential resistance.

The impending collapse of Moore-like growth of computational power has spurred the development of alternative computing architectures, such as optical or electro-optical computing. However, many of the current demonstrations in literature are not compatible with the dominant complementary metal-oxide semiconductor (CMOS) technology used in large-scale manufacturing today. Here, inspired by the famous Esaki diode demonstrating negative differential resistance (NDR), we show a fully CMOS-compatible electro-optical memory device, based on a new type of NDR diode. This new diode is based on a horizontal PN junction in silicon with a unique layout providing the NDR feature, and we show how it can easily be implemented into a photonic micro-ring resonator to enable a bistable device with a fully optical readout in the telecom regime. Our result is an important stepping stone on the way to new nonlinear electro-optic and neuromorphic computing structures based on this new NDR diode.

Quasi-guided modes resulting from the band folding effect in a photonic crystal slab for enhanced interactions of matters with free-space radiations.

We elucidate that guided modes supported by a regular photonic crystal slab structure composed of a square lattice of air holes in a silicon slab will transition into quasi-guided (leaky) modes when the radius of every second column of air holes is changed slightly. This intentional geometric perturbation will lead to a doubling of the period in one direction and the corresponding shrinkage of the first Brillouin zone. Because of the translational symmetry in the k-space, leaky waves inheriting the spatial dispersion of the original guided modes, which do not interact with external radiation, will appear with the dispersion curves above the light cone. Our results show that ultrahigh Q-factor resonances with large operating bandwidth can be achieved. Interestingly, the perturbation in only one direction of the photonic lattice will lead to an in-plane wave number-dependent resonance characteristic in both directions. Our numerical results demonstrate a local enhancement of the electric field magnitude by the order of 102, which is even more significant than those in most plasmonic structures. These quasi-guided modes with superior properties will provide a new platform for efficient light-matter interactions.

MoSe2/WS2 heterojunction photodiode integrated with a silicon nitride waveguide for near infrared light detection with high responsivity.

We demonstrate experimentally the realization and the characterization of a chip-scale integrated photodetector for the near-infrared spectral regime based on the integration of a MoSe2/WS2 heterojunction on top of a silicon nitride waveguide. This configuration achieves high responsivity of ~1 A W-1 at the wavelength of 780 nm (indicating an internal gain mechanism) while suppressing the dark current to the level of ~50 pA, much lower as compared to a reference sample of just MoSe2 without WS2. We have measured the power spectral density of the dark current to be as low as ~1 × 10-12 A Hz-0.5, from which we extract the noise equivalent power (NEP) to be ~1 × 10-12 W Hz-0.5. To demonstrate the usefulness of the device, we use it for the characterization of the transfer function of a microring resonator that is integrated on the same chip as the photodetector. The ability to integrate local photodetectors on a chip and to operate such devices with high performance at the near-infrared regime is expected to play a critical role in future integrated devices in the field of optical communications, quantum photonics, biochemical sensing, and more.

Ultra-high-Q substrate-mode coupled resonances in complementary THz metamaterial.

Achieving high-Q resonances in the THz frequency range is significant for applications such as sensors, filters, and emitters. A promising approach for obtaining such resonances is by using metamaterials. However, high-Q resonances in THz metamaterials are usually limited by metallic radiation losses in the meta-atoms. In this Letter, we investigate both experimentally and numerically a complementary metallic disk-hole array (CMA) that uses the coupling between lattice resonances and Fabry-Pérot cavity resonances, and features in-substrate modes with experimentally obtained record breaking Q-factors of up to 750. To the best of our knowledge, this is the highest quality factor measured for free-space-coupled metallic metamaterial structure at THz frequencies.

Could psychedelic drugs have a role in the treatment of schizophrenia? Rationale and strategy for safe implementation.

Schizophrenia is a widespread psychiatric disorder that affects 0.5-1.0% of the world's population and induces significant, long-term disability that exacts high personal and societal cost. Negative symptoms, which respond poorly to available antipsychotic drugs, are the primary cause of this disability. Association of negative symptoms with cortical atrophy and cell loss is widely reported. Psychedelic drugs are undergoing a significant renaissance in psychiatric disorders with efficacy reported in several conditions including depression, in individuals facing terminal cancer, posttraumatic stress disorder, and addiction. There is considerable evidence from preclinical studies and some support from human studies that psychedelics enhance neuroplasticity. In this Perspective, we consider the possibility that psychedelic drugs could have a role in treating cortical atrophy and cell loss in schizophrenia, and ameliorating the negative symptoms associated with these pathological manifestations. The foremost concern in treating schizophrenia patients with psychedelic drugs is induction or exacerbation of psychosis. We consider several strategies that could be implemented to mitigate the danger of psychotogenic effects and allow treatment of schizophrenia patients with psychedelics to be implemented. These include use of non-hallucinogenic derivatives, which are currently the focus of intense study, implementation of sub-psychedelic or microdosing, harnessing of entourage effects in extracts of psychedelic mushrooms, and blocking 5-HT2A receptor-mediated hallucinogenic effects. Preclinical studies that employ appropriate animal models are a prerequisite and clinical studies will need to be carefully designed on the basis of preclinical and translational data. Careful research in this area could significantly impact the treatment of one of the most severe and socially debilitating psychiatric disorders and open an exciting new frontier in psychopharmacology.

Enhanced Chiral Sensing at the Few-Molecule Level Using Negative Index Metamaterial Plasmonic Nanocuvettes.

Chirality is a fundamental property of biological molecules and some pharmaceutical molecules. Chiral molecules have a pair of chiral isomers (enantiomers) with opposite handedness. Although both enantiomers of the same molecule have identical chemical and physical properties, one enantiomer may be toxic to living organisms while the other one is harmless. The detection of these enantiomers is done using their small differential absorption between right and left circularly polarized light, known as circular dichroism (CD). Considering the macroscopic size of these molecules, combined with their small differential absorption, the obtained CD signal is very small, imposing a severe limitation on the minimal concentration that can be detected. Chiral plasmonic and metamaterial structures have been used to enhance the sensitivity of CD measurements by orders of magnitude through chiral density hot spots (super chiral fields). However, the large background signal due to these structures' intrinsic chirality limits the effectiveness of these methods. Contrary to absorption-based chiral sensing measurements (CD), fluorescence detection circular dichroism (FDCD) sensing can greatly improve chiral measurement sensitivity, down to the ultimate limit of a few and even a single chiral molecule. Like differential absorption, differential fluorescence also produces a weak signal at the few-chiral-molecule limit. However, here we demonstrate a negative-index metamaterial (NIM) cavity that acts as a "plasmonic nanocuvette" with globally enhanced volume super chiral fields. Moreover, the achiral structure of the plasmonic nanocuvette allows for completely background-free chiral sensing. We show that with NIM-cavity-enhanced FDCD, we can detect as low as a few tens of chiral molecules, well within the zeptomole range.

D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans.

The D-aspartate oxidase (DDO) gene encodes the enzyme responsible for the catabolism of D-aspartate, an atypical amino acid enriched in the mammalian brain and acting as an endogenous NMDA receptor agonist. Considering the key role of NMDA receptors in neurodevelopmental disorders, recent findings suggest a link between D-aspartate dysmetabolism and schizophrenia. To clarify the role of D-aspartate on brain development and functioning, we used a mouse model with constitutive Ddo overexpression and D-aspartate depletion. In these mice, we found reduced number of BrdU-positive dorsal pallium neurons during corticogenesis, and decreased cortical and striatal gray matter volume at adulthood. Brain abnormalities were associated with social recognition memory deficit at juvenile phase, suggesting that early D-aspartate occurrence influences neurodevelopmental related phenotypes. We corroborated this hypothesis by reporting the first clinical case of a young patient with severe intellectual disability, thought disorders and autism spectrum disorder symptomatology, harboring a duplication of a chromosome 6 region, including the entire DDO gene.

MEMS cantilever-controlled plasmonic colors for sustainable optical displays.

Conventional optical displays using indium tin oxide and liquid crystal materials present challenges for long-term sustainability. We show here a cost-effective and complementary metal-oxide semiconductor (CMOS)-compatible fast and full-range electrically controlled RGB color display. This is achieved by combining transmission-based plasmonic metasurfaces with MEMS (microelectromechanical systems) technology, using only two common materials: aluminum and silicon oxide. White light is filtered into RGB components by plasmonic metasurfaces made of aluminum nanohole arrays. The transmission through each color filter is modulated by MEMS miniaturized cantilevers fabricated with aluminum and silicon oxide on top of the color filters. We show that the relative transmission of a color subpixel can be freely modulated from 35 to 100%. The pixels can also operate well above 800 Hz for future ultrafast displays. Our work provides a road to future circular economic goals by exploiting advances in structural colors and MEMS technologies to innovate optical displays.

Chip-scale atomic wave-meter enabled by machine learning.

The quest for miniaturized optical wave-meters and spectrometers has accelerated the design of novel approaches in the field. Particularly, random spectrometers (RS) using the one-to-one correlation between the wavelength and an output random interference pattern emerged as a promising tool combining high spectral resolution and cost-effectiveness. Recently, a chip-scale platform for RS has been demonstrated with a markedly reduced footprint. Yet, despite the evident advantages of such modalities, they are very susceptible to environmental fluctuations and require an external calibration process. To address these challenges, we demonstrate a paradigm shift in the field, enabled by the integration of atomic vapor with a photonic chip and the use of a machine learning classification algorithm. Our approach provides a random wave-meter on chip device with accurate calibration and enhanced robustness against environmental fluctuations. The demonstrated device is expected to pave the way toward fully integrated spectrometers advancing the field of silicon photonics.

Resonant Laser Printing of Optical Metasurfaces.

One of the challenges for metasurface research is upscaling. The conventional methods for fabrication of metasurfaces, such as electron-beam or focused ion beam lithography, are not scalable. The use of ultraviolet steppers or nanoimprinting still requires large-size masks or stamps, which are costly and challenging in further handling. This work demonstrates a cost-effective and lithography-free method for printing optical metasurfaces. It is based on resonant absorption of laser light in an optical cavity formed by a multilayer structure of ultrathin metal and dielectric coatings. A nearly perfect light absorption is obtained via interferometric control of absorption and operating around a critical coupling condition. Controlled by the laser power, the surface undergoes a structural transition from random, semiperiodic, and periodic to amorphous patterns with nanoscale precision. The reliability, upscaling, and subwavelength resolution of this approach are demonstrated by realizing metasurfaces for structural colors, optical holograms, and diffractive optical elements.

Spectrally Gated Microscopy (SGM) with Meta Optics for Parallel Three-Dimensional Imaging.

Volumetric imaging with high spatiotemporal resolution is of utmost importance for various applications ranging from aerospace and defense to real-time imaging of dynamic biological processes. To facilitate three-dimensional sectioning, current technology relies on mechanisms to reject light from adjacent out-of-focus planes either spatially or by other means. Yet, the combination of rapid acquisition time and high axial resolution is still elusive, motivating a persistent pursuit for emerging imaging approaches. Here we introduce and experimentally demonstrate a concept named spectrally gated microscopy (SGM), which enables a single-shot interrogation over the full axial dimension while maintaining a submicron sectioning resolution. SGM utilizes two important features enabled by flat optics (i.e., metalenses or diffractive lenses), namely, a short focal length and strong chromatic aberrations. Using SGM we demonstrate three-dimensional imaging of millimeter-scale samples while scanning only the lateral dimension, presenting a significant advantage over state-of-the-art technology.

Demonstration of an integrated nanophotonic chip-scale alkali vapor magnetometer using inverse design.

Recently, there has been growing interest in the miniaturization and integration of atomic-based quantum technologies. In addition to the obvious advantages brought by such integration in facilitating mass production, reducing the footprint, and reducing the cost, the flexibility offered by on-chip integration enables the development of new concepts and capabilities. In particular, recent advanced techniques based on computer-assisted optimization algorithms enable the development of newly engineered photonic structures with unconventional functionalities. Taking this concept further, we hereby demonstrate the design, fabrication, and experimental characterization of an integrated nanophotonic-atomic chip magnetometer based on alkali vapor with a micrometer-scale spatial resolution and a magnetic sensitivity of 700 pT/√Hz. The presented platform paves the way for future applications using integrated photonic-atomic chips, including high-spatial-resolution magnetometry, near-field vectorial imaging, magnetically induced switching, and optical isolation.

Arbitrarily directed emission of integrated cylindrical vector vortex beams by geometric phase engineering.

Integrated cylindrical vector vortex (CVV) emitters have been introduced and studied for their potential applications in classical optics and quantum optics technologies. In this work, we demonstrate that the emission angle of integrated CVV emitters can be engineered by taking advantage of the geometrical phase of a microring resonator. Two methods to superimpose an arbitrary phase profile on top of the integrated emitters are presented and compared. Angled emission of integrated vector vortex beams enables the use of chip-scale emitters for integrated nonlinear optics and for beam steering applications with orbital angular momentum.

How good is your metalens? Experimental verification of metalens performance criterion.

A metric for evaluation of overall metalens performance is presented. It is applied to determination of optimal operating spectral range of a metalens, both theoretically and experimentally. This metric is quite general and can be applied to the design and evaluation of future metalenses, particularly achromatic metalenses.