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1.
Am J Cardiol ; 100(1): 73-5, 2007 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-17599444

RESUMO

We examined the effect of an outpatient office-based diet and exercise counseling program on weight loss and lipid levels with an onsite dietitian who sees patients at the same visit with the physician and is fully reimbursable. Eighty overweight or obese patients (average age 55 +/- 12 years, baseline body mass index 30.1 +/- 6.4 kg/m(2)) with > or =1 cardiovascular risk factor (86%) or coronary heart disease (14%) were counseled to exercise 30 minutes/day and eat a modified Dietary Approaches to Stop Hypertension (DASH) diet (saturated fat <7%, polyunsaturated fat to 10%, monounsaturated fat to 18%, low in glycemic index and sodium and high in fiber, low-fat dairy products, fruits, and vegetables). Weight, body mass index, lipid levels, and blood pressure were measured at 1 concurrent follow-up visit with the dietitian and physician and > or =1 additional follow-up with the physician. Maximum weight lost was an average of 5.6% (10.8 lb) at a mean follow-up of 1.75 years. Sixty-four (81%) of these patients maintained significant weight loss (average weight loss 5.3%) at a mean follow-up of 2.6 years. Average decrease in low-density lipoprotein cholesterol was 9.3%, average decrease in triglycerides was 34%, and average increase in high-density lipoprotein cholesterol was 9.6%. Systolic blood pressure was lowered from 129 to 126 mm Hg (p = 0.21) and diastolic blood pressure from 79 to 75 mm Hg (p = 0.003). In conclusion, having a dietitian counsel patients concurrently with a physician in the outpatient setting is effective in achieving and maintaining weight loss and is fully reimbursable.


Assuntos
Dietética , Aconselhamento Diretivo , Lipídeos/sangue , Obesidade/terapia , Redução de Peso , Adulto , Idoso , Assistência Ambulatorial , Índice de Massa Corporal , Doença das Coronárias/prevenção & controle , Dieta com Restrição de Carboidratos , Dieta com Restrição de Gorduras , Dieta Hipossódica , Terapia por Exercício , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade/dietoterapia , Resultado do Tratamento
2.
Arch Intern Med ; 167(10): 1060-7, 2007 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-17533209

RESUMO

BACKGROUND: Epidemiologic studies suggest a low incidence of cardiovascular disease in populations that consume dietary soy. For people aged 40 to 70 years, each increment of 20 mm Hg in systolic blood pressure (BP) or 10 mm Hg in diastolic BP doubles the risk of cardiovascular disease for BPs of 115/75 to 185/115 mm Hg. METHODS: To determine the effect of soy nuts on systolic and diastolic BP and lipid levels, 60 healthy postmenopausal women were randomized in a crossover design to a Therapeutic Lifestyle Changes (TLC) diet alone and a TLC diet of similar energy, fat, and protein content in which soy nuts (containing 25 g of soy protein and 101 mg of aglycone isoflavones) replaced 25 g of non-soy protein. Each diet was followed for 8 weeks. RESULTS: Compared with the TLC diet alone, the TLC diet plus soy nuts lowered systolic and diastolic BP 9.9% and 6.8%, respectively, in hypertensive women (systolic BP> or =140 mm Hg) and 5.2% and 2.9%, respectively, in normotensive women (systolic BP<120 mm Hg). Further subdivision of normotensive women revealed that systolic and diastolic BPs were lowered 5.5% and 2.7%, respectively, in prehypertensive women (systolic BP of 120-139 mm Hg) and 4.5% and 3.0%, respectively, in normotensive women. Soy nut supplementation lowered low-density lipoprotein cholesterol and apolipoprotein B levels 11% and 8% (P = .04 for both), respectively, in hypertensive women but had no effect in normotensive women. CONCLUSIONS: Substituting soy nuts for nonsoy protein in a TLC diet improves BP and low-density lipoprotein cholesterol levels in hypertensive women and BP in normotensive postmenopausal women. These findings may explain a cardioprotective effect of soy.


Assuntos
Pressão Sanguínea/fisiologia , Hipertensão/dietoterapia , Lipídeos/sangue , Alimentos de Soja , Adulto , Idoso , Apolipoproteínas B/sangue , Glicemia/análise , Estudos Cross-Over , Dieta , Suplementos Nutricionais , Exercício Físico , Feminino , Humanos , Hipertensão/fisiopatologia , Isoflavonas/urina , Pessoa de Meia-Idade , Pós-Menopausa
3.
J Womens Health (Larchmt) ; 16(3): 361-9, 2007 04.
Artigo em Inglês | MEDLINE | ID: mdl-17439381

RESUMO

BACKGROUND: Epidemiological studies suggest a low incidence of hot flashes in populations that consume dietary soy. The present study examined the effect of soy nuts on hot flashes and menopausal symptoms. METHODS: Sixty healthy postmenopausal women were randomized in a crossover design to a therapeutic lifestyle changes (TLC) diet alone and a TLC diet of similar energy, fat, and protein content in which one-half cup soy nuts divided into three or four portions spaced throughout the day (containing 25 g soy protein and 101 mg aglycone isoflavones) replaced 25 g of nonsoy protein. During each 8-week diet period, subjects recorded the number of hot flashes and amount of exercise daily. At the end of each 8-week diet period, subjects filled out the menopausal symptom quality of life questionnaire. RESULTS: Compared to the TLC diet alone, the TLC diet plus soy nuts was associated with a 45% decrease in hot flashes (7.5 +/- 3.6 vs. 4.1 +/- 2.6 hot flashes day, respectively, p < 0.001) in women with >4.5 hot flashes/day at baseline and 41% in those with

Assuntos
Glycine max , Fogachos/tratamento farmacológico , Isoflavonas/administração & dosagem , Menopausa , Proteínas de Soja/administração & dosagem , Saúde da Mulher , Estudos Cross-Over , Feminino , Fogachos/urina , Humanos , Isoflavonas/urina , Pessoa de Meia-Idade , Nozes , Fitoterapia , Qualidade de Vida , Valores de Referência , Resultado do Tratamento
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