RESUMO
Solution-based and solid-state reactions of copper(ii) compounds, 1,10-phenanthroline and l-threonine were investigated. Eight new ternary coordination compounds were obtained: [Cu(l-Thr)(H2O)(phen)]2SO4â10H2O (1aâ10H 2 O), [Cu(l-Thr)(H2O) (phen)]2SO4â4.3H2O (1aâ4.3H 2 O), {[Cu(µ-l-Thr)(phen)]2SO4â3.5H2O} n (1bâ3.5H 2 O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4â2H2OâCH3OH (1câ2H 2 OâCH 3 OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4â4H2O (1câ4H 2 O), [Cu(l-Thr)(CH3OH)(phen)]2SO4âH2O (1dâH 2 O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)][Cu(SO4)(l-Thr)(phen)]HSO4âH2Oâ3CH3OH (1e·H 2 O·3CH 3 OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(phen)(py)]SO4 (1f) (phen = 1,10-phenanthroline, l-Thr = l-threoninate, py = pyridine). X-ray crystal structure analysis of the prepared ternary coordination compounds revealed extensive hydrogen bonding and π-interactions that link complex species, anions and solvent molecules into 3D architectures. The water/methanol solvent molecules are found in pockets and/or channels in seven solvates. ESR spectra of different types of compounds were also investigated. In all measured compounds the unpaired electron of the copper(II) ion is located in the dx2-y2 orbital which is in agreement with elongated square-pyramidal geometry. Compound 1aâ10H 2 O showed substantial cytotoxic activity toward human hepatocellular carcinoma (HepG2) and acute monocytic leukaemia (THP-1) cell lines.