1.
Molecules
; 21(1): E112, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26797597
RESUMO
An enantioselective total synthesis of chiral falcarindiol analogues from buta-1,3-diyn-1-yltriisopropylsilane is reported. The key step in this synthesis is BINOL-promoted asymmetric diacetylene addition to aldehydes. The two chiral centers of the falcarindiol analogues can be produced by using the same kind of catalyst with high selectivity, and the final product can be obtained in only six steps.