1.
Org Lett
; 2(4): 563-4, 2000 Feb 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10814377
RESUMO
[reaction: see text] A new and highly versatile source of difluorocarbene is reported. Trimethylsilyl fluorosulfonyldifluoroacetate (TFDA) undergoes decomposition in the presence of catalytic fluoride to form difluorocarbene under conditions that allow its addition to relatively electron deficient alkenes in high yield. For example, unprecedented CF2: addition to n-butyl acrylate proceeded in 73% yield.