RESUMO
This paper focuses on the collective dynamics of multisynchronization among heterogeneous genetic oscillators under a partial impulsive control strategy. The coupled nonidentical genetic oscillators are modeled by differential equations with uncertainties. The definition of multisynchronization is proposed to describe some more general synchronization behaviors in the real. Considering that each genetic oscillator consists of a large number of biochemical molecules, we design a more manageable impulsive strategy for dynamic networks to achieve multisynchronization. Not all the molecules but only a small fraction of them in each genetic oscillator are controlled at each impulsive instant. Theoretical analysis of multisynchronization is carried out by the control theory approach, and a sufficient condition of partial impulsive controller for multisynchronization with given error bounds is established. At last, numerical simulations are exploited to demonstrate the effectiveness of our results.
RESUMO
The genetic regulatory networks are complex dynamic systems which reflect various kinetic behaviors of living things. In this paper, a new structure of coupled repressilators is introduced to exploit the underlying functions. The new coupled repressilator model consists of two identical repressilators inhibiting each other directly. The coupling delays are taken into account. The existence of a unique equilibrium for this system is verified firstly, then the stability criteria for equilibrium are analyzed without and with coupling delays. The different functions on equilibrium and its stability played by related biochemical parameters in the structure including maximal transcription rate, coupling strength, the decay rate ratio between proteins and mRNAs, and coupling delays are discussed. At last, several numerical simulations are made to demonstrate our results.
