Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 13 de 13
Filtrar
Mais filtros











Base de dados
Intervalo de ano de publicação
1.
Eur J Microbiol Immunol (Bp) ; 5(2): 164-71, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26185685

RESUMO

Through a cross-sectional study design, 150 women attending public health centers with a history of stillbirths were examined for anti-Toxoplasma gondii IgG and IgM antibodies in Durango City, Mexico. Bivariate and multivariate analyses were used to assess the association of T. gondii seropositivity with the characteristics of the women with stillbirth history. Of the 150 women (mean age: 32.09 ± 9.16 years) studied, 14 (9.3%) had anti-T. gondii IgG antibodies and six (42.9%) of them were also positive for anti-T. gondii IgM antibodies. Multivariate analysis showed that T. gondii seropositivity was associated with high frequency (4-7 days a week) of eating meat (OR = 5.52; 95% CI: 1.48-20.59; P = 0.01), history of lymphadenopathy (OR = 4.52; 95% CI: 1.14-17.82; P = 0.03), and history of surgery (OR = 8.68; 95% CI: 1.04-72.15; P = 0.04). This is the first study on the seroepidemiology of T. gondii infection in women with a history of stillbirths in Mexico. The association of T. gondii exposure with a history of surgery warrants for further research. Risk factors for T. gondii infection found in the present survey may help to design optimal educational programs to avoid T. gondii infection.

2.
Eur J Microbiol Immunol (Bp) ; 4(2): 117-22, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24883197

RESUMO

Through a cross-sectional study design, 326 women with a history of miscarriage were examined for anti-Toxoplasma gondii IgG and IgM antibodies in Durango City, Mexico. Prevalence association with sociodemographic, clinical, and behavioral characteristics in women with miscarriage was also investigated. Twenty-two (6.7%) of the 326 women studied had anti-T. gondii IgG antibodies and two (0.6%) were also positive for anti-T. gondii IgM antibodies. Seroprevalence of T. gondii infection was not influenced by age, birth place, occupation, educational level, or socioeconomic status. In contrast, logistic regression showed that T. gondii exposure was associated with consumption of raw or undercooked meat (OR = 6.84; 95% CI: 1.04-44.95; P = 0.04) and consumption of chicken brains (OR = 18.48; 95% CI: 1.26-269.43; P = 0.03). This is the first study on the seroepidemiology of T. gondii infection in women with a history of miscarriage in Northern Mexico. Of interest, we also observed an association of T. gondii exposure with consumption of chicken brains. Contributing factors for T. gondii exposure found in the present study should be taken into consideration for public health measures to avoid infection with T. gondii and its sequelae.

3.
Eur J Microbiol Immunol (Bp) ; 4(1): 76-82, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24678408

RESUMO

PURPOSE: The seroprevalence of infection with the parasite Toxoplasma gondii and the association with risk factors has not been determined in inmates. Through a case-control study, 166 inmates from a state correctional facility in Durango City, Mexico and 166 age- and gender-matched non-incarcerated subjects were examined for the presence of anti-T. gondii IgG and IgM antibodies using enzyme-linked immunoassays. RESULTS: Seroprevalence of anti-T. gondii IgG antibodies was higher in inmates (35, 21.1%) than in controls (14, 8.4%) (OR = 2.90; 95% CI: 1.43-5.94; P = 0.001). Anti-T. gondii IgM antibodies were detected in two (1.2%) inmates and in seven (4.2%) controls (P = 0.17). Multivariate analysis of socio-demographic, incarceration, and behavioral characteristics of inmates revealed that T. gondii seropositivity was associated with being born out of Durango State (OR = 3.91; 95% CI: 1.29-11.79; P = 0.01). In addition, T. gondii seroprevalence was higher (P = 0.03) in inmates that had suffered from injuries (17/56: 30.4%) than those without such history (18/110: 16.4%). CONCLUSIONS: The seroprevalence of T. gondii infection in inmates in Durango City is higher than the seroprevalences found in the general population in the same city, indicating that inmates may represent a new risk group for T. gondii infection. Further research on T. gondii infection in inmates is needed.

4.
Occup Med (Lond) ; 61(4): 265-9, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21515666

RESUMO

BACKGROUND: Raw meat may contain viable Toxoplasma gondii tissue cysts and therefore handling of raw meat may represent a risk for T. gondii infection. AIMS: To determine the association of T. gondii infection with occupational exposure to raw meat. METHODS: Case-control seroprevalence study design with enzyme-linked immunoassays for the presence and levels of anti-Toxoplasma IgG antibodies and for the presence of anti-Toxoplasma IgM antibodies. Those occupationally exposed to raw meat consisted of butchers working in two abattoirs and 35 butcher's shops in Durango, Mexico. The control group consisted of individuals from the general population from the same region. Socio-demographic, work, clinical and behavioural characteristics from each butcher were obtained. RESULTS: One hundred and twenty-four workers occupationally exposed to raw meat and 248 control subjects were examined. Eight (7%) of the butchers and 22 (9%) of the controls were positive for anti-T. gondii IgG antibodies [not statistically significant (NS)]. Anti-T. gondii IgG levels were >150 IU/ml in 7 (6%) butchers and 14 (6%) controls (NS). Anti-T. gondii IgM antibodies were found in five (4%) of the butchers and four (2%) of the controls (NS). None of the factors examined appeared to predict seropositivity although both butchers who reported consuming dried beef were seropositive compared to 6/122 controls (95% CI 0.60-1.29). CONCLUSIONS: Occupational exposure to raw meat was not associated with seropositivity for T. gondii infection. Consumption of dried beef may warrant further investigation.


Assuntos
Matadouros , Indústria de Processamento de Alimentos , Carne/parasitologia , Doenças Profissionais/epidemiologia , Exposição Ocupacional/efeitos adversos , Toxoplasmose/epidemiologia , Adolescente , Adulto , Idoso , Animais , Anticorpos Antiprotozoários/sangue , Estudos de Casos e Controles , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Análise Multivariada , Prevalência , Estudos Soroepidemiológicos , Adulto Jovem
5.
J Parasitol ; 97(1): 40-3, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21348604

RESUMO

There is a lack of information about the seroepidemiology of T. gondii infection in the general population of Durango City, Mexico. Anti- Toxoplasma gondii IgG and IgM antibodies were sought in 974 inhabitants in Durango City, Mexico with the use of enzyme-linked immunoassays. in total, 59 (6.1%) of 974 participants (mean age 37 ± 16.1 yr) had IgG anti- T. gondii antibodies. Twenty (2.1%) of them also had IgM anti- T. gondii antibodies. IgG levels of 13-99, 100-150, and >150 International Units (IU)/ml were found in 14 (23.7%), 3 (5.1%), and 42 (71.2%) anti- T. gondii IgG-positive participants, respectively. Prevalence of infection increased with age (P < 0.05), and was significantly lower in participants born in Durango State than those born in other Mexican states (P < 0.01). Toxoplasma gondii infection was significantly associated with consumption of boar meat (adjusted odds ratio [OR]  =  3.02; 95% confidence interval [CI]: 1.49-6.13), and squirrel meat (adjusted OR  =  2.18; 95% CI: 1.17-4.09). in addition, infection was negatively associated with travel abroad (adjusted OR  =  0.42; 95% CI: 0.23-0.77), and salami consumption (adjusted OR  =  0.57; 95% CI: 0.32-0.99). This is the first report of seroprevalence and contributing factors for T. gondii infection in general population in Durango City, and of an association of the consumption of boar meat with T. gondii infection. This study provides a basis for the design of successful preventive measures against T. gondii infection.


Assuntos
Anticorpos Antiprotozoários/sangue , Toxoplasma/imunologia , Toxoplasmose/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Animais , Criança , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Carne , México/epidemiologia , Pessoa de Meia-Idade , Prevalência , Características de Residência , Fatores de Risco , Sciuridae , Estudos Soroepidemiológicos , Suínos , Adulto Jovem
6.
J Parasitol ; 96(5): 847-50, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20950091

RESUMO

Water, sewage, and soil are potential sources of infection for Toxoplasma gondii. Therefore, we sought to determine the prevalence of T. gondii infection and associated characteristics in 61 plumbers, 203 construction workers, and 168 gardeners in Durango City, Mexico. Participants were tested for T. gondii IgG and IgM antibodies with the use of enzyme-linked immunoassays. In addition, sociodemographic, clinical, and behavioral characteristics from each participant were obtained. IgG T. gondii antibodies were found in 4 (6.6%) plumbers, 17 (8.4%) construction workers, and 10 (6.0%) gardeners; T. gondii IgM antibodies were found in 3 (1.5%) construction workers and 4 (2.4%) gardeners, but in none of the plumbers. In the total population, the prevalence of T. gondii infection was significantly higher in workers living in suburban areas, without education, workers that consumed chorizo, and those who suffered from any disease (P < 0.05). In gardeners, prevalence of infection was significantly higher in those with blood transfusion, and memory impairment (P < 0.05). Multivariate analysis showed that T. gondii infection was positively associated with consumption of unwashed fruits (adjusted odds ratio [OR]  =  2.41; 95% confidence interval [CI]: 1.13-5.13), and with raising animals (adjusted OR  =  2.53; 95% CI: 1.00-6.37). This is the first report of contributing factors for T. gondii infection in workers occupationally exposed to water, sewage, and soil in a Mexican city, and results will contribute to the design of optimal preventive measures.


Assuntos
Anticorpos Antiprotozoários/sangue , Doenças Profissionais/epidemiologia , Toxoplasma/imunologia , Toxoplasmose/epidemiologia , Adulto , Arquitetura de Instituições de Saúde , Comportamento Alimentar , Feminino , Jardinagem , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Doenças Profissionais/parasitologia , Engenharia Sanitária , Estudos Soroepidemiológicos , Esgotos/parasitologia , Solo/parasitologia , Toxoplasmose/etiologia , Viagem , Água/parasitologia
7.
J Parasitol ; 96(3): 505-8, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20557194

RESUMO

Toxoplasma gondii infection may cause a variety of symptoms involving virtually all organs. Little is known of the epidemiology of T. gondii infection in different patient groups in Mexico. We sought to determine the prevalence of T. gondii infection and associated epidemiological characteristics in 472 patients in Durango, Mexico. Participants were tested for T. gondii IgG and IgM antibodies. In addition, sociodemographic, clinical, and behavioral characteristics from each participant were obtained. Seroprevalences of T. gondii IgG antibodies were found in 7 (8.2%) of 85 patients with hearing impairment, 5 (10.0%) of 50 patients with hemodialysis, 28 (12.0%) of 234 patients with visual impairment, and 7 (6.8%) of 103 at risk of immunosuppression. In total, 47 (10%) of 472 subjects had IgG T. gondii antibodies; 6 (1.3%) of them also had IgM anti- T. gondii antibodies. Patients born in Durango State had a significantly lower prevalence of T. gondii infection than patients born in other Mexican states (9.0% vs. 21.4%, respectively; P < 0.05). Multivariate analysis showed that T. gondii infection was significantly associated with consumption of undercooked meat (adjusted odds ratio [OR] = 2.95; 95% confidence interval [CI]: 1.18-7.35) or raw cow's milk (adjusted OR = 2.52; 95% CI: 1.28-4.96), presence of cats at home (adjusted OR = 2.01; 95% CI: 1.06-3.78), raising animals (adjusted OR = 2.44; 95% CI: 1.06-5.63), or eating away from home (adjusted OR = 2.70; 95% CI: 1.03-7.11). In the group of patients with visual impairment, those with reflex impairment had a significantly higher frequency of T. gondii infection than those with normal reflexes (19% vs. 9.4%, respectively: P = 0.04). Results of the present study are the first step in the design of prevention programs to avoid the sequelae of toxoplasmosis.


Assuntos
Anticorpos Antiprotozoários/sangue , Toxoplasma/imunologia , Toxoplasmose/complicações , Toxoplasmose/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Gatos , Criança , Pré-Escolar , Feminino , Infecções por HIV/complicações , Transtornos da Audição/complicações , Humanos , Hospedeiro Imunocomprometido , Modelos Logísticos , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Neoplasias/complicações , Diálise Renal , Insuficiência Renal/complicações , Insuficiência Renal/terapia , Fatores de Risco , Estudos Soroepidemiológicos , Toxoplasmose/imunologia , Transtornos da Visão/complicações , Adulto Jovem
8.
J Parasitol ; 96(5): 941-5, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20481662

RESUMO

There is a lack of information concerning the epidemiology of Toxoplasma gondii infection in Mennonites (an ethnic group of Mexican citizens of German descent living in rural communities). The prevalence of anti- T. gondii immunoglobulin (Ig) G and IgM antibodies was examined in 152 Mennonites in Durango State, Mexico, using enzyme-linked immunoassays. In total, 46 (30.3%) of 152 participants (mean age 38.4 ± 15.5 yr) had IgG T. gondii antibodies; 5 (3.3%) also had IgM T. gondii antibodies. Toxoplasma gondii infection was significantly associated with the presence of cats at home (adjusted OR  =  3.93; 95% CI: 1.40-11.05), raising cattle (adjusted OR  =  3.88; 95% CI: 1.24-12.11), consumption of pigeon meat (adjusted OR  =  3.0; 95% CI: 1.36-6.63), and consumption of untreated water (adjusted OR  =  2.42; 95% CI: 1.09-5.40). This is the first report of seroprevalence and contributing factors for T. gondii infection in Mennonites and of an association of the consumption of pigeon meat with T. gondii infection. Results of this study should be useful in the design of optimal preventive measures against T. gondii infection.


Assuntos
Anticorpos Antiprotozoários/sangue , Toxoplasma/imunologia , Toxoplasmose/etnologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Gatos , Bovinos , Columbidae , Estudos Transversais , Comportamento Alimentar , Feminino , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Estilo de Vida , Masculino , Carne/classificação , Carne/parasitologia , México/epidemiologia , Pessoa de Meia-Idade , Protestantismo , Fatores de Risco , Estudos Soroepidemiológicos , Fatores Socioeconômicos , Perus , Adulto Jovem
9.
J Parasitol ; 95(2): 271-4, 2009 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-18922040

RESUMO

The epidemiology of Toxoplasma gondii infection in pregnant women in rural Mexico is largely unknown. The seroepidemiology of T. gondii infection in 439 pregnant women from 9 communities in rural Durango State, Mexico was investigated. Using commercial enzyme-linked immunoassays, sera were tested for T. gondii IgG, IgM, and avidity antibodies. Prevalences of T. gondii IgG antibodies in the communities varied from 0% to 20%. Overall, 36 (8.2%) of the 439 women had IgG T. gondii antibodies. Ten (2.3%) women had also T. gondii IgM antibodies; IgG avidity was high in all IgM-positive women, suggesting chronic infection. None of the women, however, had delivered a known T. gondii-infected child. The seroprevalence was significantly higher (P < 0.05) in women from low socio-economic conditions (14%) than in those with higher socio-economic status (6.6%). Multivariate analysis showed that T. gondii infection was associated with soil floors at home (adjusted OR = 2.89; 95% CI: 1.12-7.49). This is the first epidemiological study of T. gondii infection in pregnant women in rural Mexico.


Assuntos
Anticorpos Antiprotozoários/sangue , Complicações Parasitárias na Gravidez/epidemiologia , Toxoplasma/imunologia , Toxoplasmose/epidemiologia , Adolescente , Adulto , Animais , Afinidade de Anticorpos , Feminino , Pisos e Cobertura de Pisos , Habitação , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , México/epidemiologia , Gravidez , Fatores de Risco , População Rural , Estudos Soroepidemiológicos , Fatores Socioeconômicos , Adulto Jovem
10.
J Parasitol ; 94(4): 811-6, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-18576838

RESUMO

There is scarce information concerning the epidemiology of Toxoplasma gondii infection in people of rural Mexico. Anti-T. gondii immunoglobulin (Ig)G and IgM antibodies were sought in 462 adult inhabitants from 3 rural communities of Durango, Mexico, using enzyme-linked immunoassays. In total, 110 (23.8%) of 463 persons had IgG anti-T. gondii antibodies. Ten (2.2%) of them also had IgM anti-T. gondii antibodies. Prevalences of T. gondii IgG antibodies in the 3 communities varied from 14.8 to 35.8%. The highest prevalence of infection was observed in participants older than 70 yr and in those with good housing conditions. Toxoplasma gondii infection was significantly associated with consumption of squirrel (adjusted odds ratio [OR] = 4.22; 95% confidence interval [CI] = 1.11-16.05) and turkey meat (adjusted OR = 4.58; 95% CI = 1.14-18.44). This is the first epidemiological study of T. gondii prevalence in rural Mexico.


Assuntos
Anticorpos Antiprotozoários/sangue , População Rural/estatística & dados numéricos , Toxoplasma/imunologia , Toxoplasmose/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Animais , Estudos Transversais , Escolaridade , Feminino , Habitação/normas , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Masculino , Carne/classificação , México/epidemiologia , Pessoa de Meia-Idade , Estudos Soroepidemiológicos , Distribuição por Sexo
11.
Zoonoses Public Health ; 55(6): 306-12, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-18489540

RESUMO

Municipal waste is a potential source of infection for Toxoplasma gondii as it may contain contaminated meat with parasite tissue cysts and cat excrement with parasite oocysts. Therefore, we sought to determine the prevalence of T. gondii infection and associated characteristics in two populations exposed to municipal solid waste in Durango, Mexico. Ninety waste pickers and 83 waste workers of Durango City, Mexico were examined for T. gondii infection. They were tested for anti-T. gondii IgG and IgM antibodies using enzyme-linked immunoassays. In addition, socio-demographic and behavioural characteristics from each participant were obtained. Nineteen (21.1%) of the 90 waste pickers and seven (8.4%) of the 83 waste workers were positive for anti-T. gondii IgG antibodies. The difference in prevalence among the groups was statistically significant (P =0.03). Waste pickers aged 31-50 years showed a significantly higher prevalence (40.9%) than waste workers of the same age group (2.9%, P < 0.001). Anti-T. gondii IgM antibodies were found in two (2.2%) of the waste pickers but in none of the waste workers. The seroprevalence of T. gondii was significantly higher in workers of the waste transfer station (25.0%) than in drivers or helpers of waste vehicles (2.5%) (P =0.03). Multivariate analysis showed that T. gondii infection was associated with consuming food found in the garbage [adjusted odds ratio (OR) = 4.4; 95% confidence interval (CI) 1.6-11.8] and with lack of education (adjusted OR = 3.2; 95% CI 1.1-8.8). From this study, we conclude: (i) waste pickers may represent a risk group for T. gondii infection; (ii) lack of education might be a contributing factor for T. gondii infection; (iii) the higher the exposure to garbage, the higher the seroprevalence of T. gondii infection; (iv) Eating food products from the garbage may represent an important route for T. gondii infection.


Assuntos
Anticorpos Antiprotozoários/sangue , Contaminação de Alimentos/análise , Higiene , Doenças Profissionais/epidemiologia , Toxoplasma/imunologia , Toxoplasmose/epidemiologia , Adulto , Animais , Gatos , Escolaridade , Feminino , Contaminação de Alimentos/prevenção & controle , Parasitologia de Alimentos , Humanos , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Doenças Profissionais/prevenção & controle , Exposição Ocupacional , Fatores de Risco , Estudos Soroepidemiológicos , Toxoplasmose/prevenção & controle , Zoonoses
12.
J Parasitol ; 93(5): 1033-5, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18163336

RESUMO

Toxoplasma gondii and Neospora caninum are structurally similar parasites, with many hosts in common. The prevalence of antibodies to T. gondii and N. caninum was determined in sera from dogs from Durango City, Mexico. Using a modified agglutination test, antibodies to T. gondii were found in 52 (51.5%) of the 101 dogs with titers of 1:25 in 27, 1:50 in 11, 1:100 in 5, 1:200 in 4, 1:400 in 2, 1:800 in 2, and 1:3,200 or higher in 1. Antibodies to N. caninum were determined by the indirect immunofluorescent antibody test (IFAT) and the Neospora sp. agglutination test (NAT). Two of the 101 dogs had N. caninum antibodies; these dogs did not have T. gondii antibodies, supporting the specificity of the tests used. The N. caninum antibody titers of the 2 dogs were: 1:400 by IFAT and 1:200 by NAT in 1, and 1:25 by NAT and IFAT in the other. Results indicate that these 2 structurally similar protozoans are antigenically different.


Assuntos
Anticorpos Antiprotozoários/sangue , Coccidiose/veterinária , Doenças do Cão , Neospora/imunologia , Toxoplasma/imunologia , Toxoplasmose Animal/epidemiologia , Animais , Coccidiose/epidemiologia , Coccidiose/parasitologia , Doenças do Cão/epidemiologia , Doenças do Cão/parasitologia , Cães , Feminino , Masculino , México/epidemiologia , Prevalência , Toxoplasmose Animal/parasitologia
13.
J Parasitol ; 93(5): 1214-6, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18163360

RESUMO

The prevalence of antibodies to Toxoplasma gondii was determined in sera from 105 domestic cats from Durango City, Mexico. Using a modified agglutination test, antibodies to this parasite were found in 21% of the 105 cats, with titers of 1:25 in 3 cats, 1:50 in 4 cats, 1:200 in 5 cats, 1:400 in 2 cats, 1:800 in 2 cats, 1:1,600 in 4 cats, and 1:3,200 or higher in 2 cats. Cats older than 1 yr had a significantly higher frequency of infection than that found in cats younger than 0.5 yr (41 vs. 13.2%, respectively; odds ratio = 4.55; 95% CI = 1.24-17.18; P = 0.01). Overall, the seroprevalence of T. gondii antibodies in cats in Durango, Mexico, is much lower compared with those reported in other countries.


Assuntos
Anticorpos Antiprotozoários/sangue , Doenças do Gato/epidemiologia , Toxoplasma/imunologia , Toxoplasmose Animal/epidemiologia , Animais , Doenças do Gato/imunologia , Doenças do Gato/parasitologia , Gatos , Feminino , Masculino , México/epidemiologia , Estudos Soroepidemiológicos , Toxoplasmose Animal/imunologia , Toxoplasmose Animal/parasitologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA