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Virchows Arch ; 449(3): 367-72, 2006 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-16855839

RESUMO

Synovial sarcoma arising in the abdominal wall is a rare tumor. We report a case of a 38-year-old man who complained of abdominal pain. Physical examination revealed a firm mobile mass, 25 cm in diameter, in the left lower abdominal wall. The tumor was first thought to be a sarcoma arising from the omentum or mesentery. During surgery, a large tumor was found attached to the inner surface of the abdominal wall and compressing the gastrointestinal tract. On microscopic examination the tumor corresponded to a biphasic synovial sarcoma immunoreactive for cytokeratins (AE1/AE3, 7 and 19), epithelial membrane antigen and carcinoembryonic antigen in the epithelial tumor cells, for E-cadherin especially in their glandular structure, vimentin, CD99, and CD56 in the spindle cell component and for bcl-2 protein. The tumor recurred at the same site, and clinical course progressed to death 3 months after the initial diagnosis.


Assuntos
Neoplasias Abdominais/patologia , Parede Abdominal/patologia , Carcinossarcoma/patologia , Sarcoma Sinovial/patologia , Antígeno 12E7 , Neoplasias Abdominais/química , Neoplasias Abdominais/cirurgia , Parede Abdominal/cirurgia , Adulto , Antígenos CD/análise , Biomarcadores Tumorais/análise , Antígeno CD56/análise , Caderinas/análise , Antígeno Carcinoembrionário/análise , Carcinossarcoma/química , Carcinossarcoma/cirurgia , Moléculas de Adesão Celular/análise , Evolução Fatal , Humanos , Queratinas/análise , Masculino , Recidiva Local de Neoplasia , Sarcoma Sinovial/química , Sarcoma Sinovial/cirurgia , Tomografia Computadorizada por Raios X , Vimentina/análise
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