Monkeypox - A danger approaching Asia.

Since the end of June 2022, there has been a dramatic increase in the number of monkeypox cases worldwide. Given the potential spread of this epidemic, WHO has declared the monkeypox epidemic a global public health emergency. In the face of the changing epidemiology during this monkeypox outbreak, vaccines and preventive measures are being researched around the world in response to this emerging disease. Recently, confirmed cases were reported in South Korea and Japan; as connections between countries around the world resume, imported cases may be inevitable. China is also concerned and prepared for the danger approaching Asia. In response to this risk, China issued the "Monkeypox Diagnosis and Treatment Guidelines" and the General Administration of Customs of China announced that travelers from countries reporting monkeypox cases and with suspected symptoms should be identified to customs upon entry. Chinese researchers have recently generated two pseudovirus reference materials for the monkeypox viral wild-type B6R gene and mutant F3L gene. Moreover, monkeypox as a communicable disease can be added to the current COVID-19 tracking system for better surveillance and management.

Monkeypox claims new victims: the outbreak in men who have sex with men.

Monkeypox has a very prominent regional epidemic. It has been confined to Western and Central African countries. Sporadic cases found in countries outside Africa generally have a history of sojourn in endemic areas. However, the recent multinational outbreak of monkeypox cases in Europe in early May 2022 has revealed a changing epidemiological trend, those confirmed cases had no sojourn history in endemic areas and with a high proportion of cases involving men who have sex with men (MSM). Among the MSM cases, many of them presented atypical clinical manifestations of monkeypox and with other sexually transmitted diseases co-infection. Combined with the high social interactivity in this community, there is likely a higher risk of monkeypox transmission in this population. Establishing an infectious disease surveillance system, maintaining highly vigilant regarding the transmission of monkeypox in MSM, and responding promptly are necessary and effective measures to contain the outbreak.