RESUMO
An animal study was undertaken to develop a balloon dilation technique that could be used in humans to treat the common ailment of benign prostatic hypertrophy. Dogs were used as a model because of the similarities in the prostate between the two species and the ready availability of the canines. A retrograde transurethral approach was used for dilation. Balloon catheters, 8-20 mm in diameter, were used. Significant, long-lasting dilatation of the prostatic urethra was not accomplished until 20-mm balloons (or two 10-mm ones) inflated for 10 minutes were used. The animals were followed for up to 14 months. No deleterious histologic effects of dilation were identified within the urethra or prostate that could lead to stenosis of the prostatic urethra in later stages.
Assuntos
Hiperplasia Prostática/cirurgia , Cateterismo Urinário , Animais , Dilatação , Cães , Masculino , Uretra/cirurgiaRESUMO
Phagocytosis was evaluated in nine patients with splenctomy undergoing renal transplant, eight renal transplanted patients without splenectomy, three immunodepressed patients with terminal renal failure, four patients with splenectomy and six healthy volunteers. For phagocytosis evaluation, neutrophils adhered to glass were used. They were cover with 4% latex and albumin containing culture medium with or without phagocytosis stimulating tetrapeptide extracted from IgG in each case. Phagocytosis was decreased in all groups studied. Immunodepressed patients showed the highest diminishment of phagocytosis and patients with splenectomy and immunodepression the lesser. It was speculated that such a finding is due to a decrease of tetrapeptide in serum.
