The Influence of Knowledge Base on the Dual-Innovation Performance of Firms.

Dual innovation, which includes exploratory innovation and exploitative innovation, is crucial for firms to obtain a sustainable competitive advantage. The knowledge base of firms greatly influences or even determines the scope, direction, and path of their dual-innovation activities, which drive their innovation process and produce different innovation performances. This study uses data source patents obtained by 285 focal firms in the Chinese new-energy vehicle industry in the period 2015-2020. Five knowledge-base features are selected by analyzing the correlation and multicollinearity, and four different firm clusters are found by using the k-means clustering algorithm. Based on the classification and regression tree (CART) algorithm, we mine the potential decision rules governing the dual-innovation performance of firms. The results show that the exploratory innovation performance of firms in different clusters is mainly affected by two different knowledge-base features. Knowledge-base scale is a key factor affecting the exploitative innovation performance of firms. Firms in different clusters can improve their dual-innovation performance by rationally tuning the combination of knowledge-base features.

The Impact of Specialized Knowledge Search on Enterprise Innovation.

Against the backdrop of the fierce competition in the market nowadays, a closed innovation model based on internal knowledge is no longer sufficient to support enterprises in search of high-performance innovation. Instead, corporations are desperately required to search for resources of external knowledge to meet their innovation goals. Existing studies on open innovation in corporate management failed to fully elaborate on the mechanism of how the external knowledge search could impose an impact on sustaining innovation and disruptive innovation. In this study, the external knowledge search was divided into three categories according to the knowledge-based theory, namely, the scientific knowledge search, the market knowledge search, and the supply-chain knowledge search. While taking into account the moderating role of the focus of attention of the manager, we analyzed the statistical results of 485 questionnaires collected from manufacturing enterprises to elaborate on the mechanism of how the specialized knowledge search could impose an impact on sustaining innovation and disruptive innovation. Our research conclusions are expected to enrich existing studies on the factors contributing to corporate innovation, including but not limited to sustaining innovation and disruptive innovation. In addition, the research findings are expected to lay an empirical foundation by summarizing previous theoretical opinions while providing references for subsequent in-depth studies in the meantime. Moreover, the paper has put forward practical management measures and suggestions that could enable enterprises in developing countries to search and effectively transform the external knowledge into innovative outcomes. Last but not least, this study is expected to provide both theoretical and practical guidance for enterprises to further facilitate innovation by means of knowledge search.

When and How Workplace Helping Promotes Deviance? An Actor-Centric Perspective.

Despite the vast academic interest in workplace helping, little is known about the impact of different types of helping behaviors on physiological and behavioral ramifications of helpers. By taking the actor-centric perspective, this study attempts to investigate the differential impacts of three kinds of helping behaviors (caring, coaching, and substituting helping) on helpers themselves from the theory of resource conservation. To test our model, 512 Chinese employees were surveyed, utilizing a three-wave time-lagged design, and we found that caring and coaching helping were negatively associated with workplace deviance, whereas substituting helping was positively associated with subsequent workplace deviance. Emotional exhaustion mediated the effects of three helping behaviors on subsequent workplace deviance. Moreover, employees' extrinsic career goals influenced the strength of the relationship between three helping behaviors and emotional exhaustion and the indirect effects of three helping behaviors on subsequent workplace deviance via emotional exhaustion. We discuss the implications of our findings for both theories and practices.

Research on the Effects of Entrepreneurial Education and Entrepreneurial Self-Efficacy on College Students' Entrepreneurial Intention.

Entrepreneurship is one of the important engines of economic development. Under the influence of policy encouragement and economic situation, college students have become the emerging entrepreneurial subjects. Studying the factors influencing their willingness to innovate is conducive to improving the entrepreneurial status and performance. From the perspective of planned behavior theory, this paper analyzes the effects of college students' entrepreneurship education and self-efficacy on their entrepreneurial intention. Using a sample of 327 college students in China, we test the hypotheses, and get some results. Firstly, college students' entrepreneurial education has a significant positive effect on their entrepreneurial intention, but has no obvious effect on the entrepreneurial attitude. Secondly, college students' entrepreneurial self-efficacy has a significant positive effect on the entrepreneurial attitude and entrepreneurial intention, and the entrepreneurial attitude plays a partial intermediary role in the relationship between entrepreneurial self-efficacy and entrepreneurial intention.

The dentin permeability of anti-inflammatory and antibacterial drugs: In vitro study.

BACKGROUND/PURPOSE: Stimuli from the oral cavity may penetrate through exposed dentinal tubules and evoke inflammatory pulp response. Anti-bacterial and anti-inflammatory drugs applied to exposed dentin may infiltrate through the dentinal tubules and cause pulp recovery. This study investigated the dentin permeability of anti-bacterial and anti-inflammation drugs via an in-vitro transwell dentin disc tube model. METHODS: Twenty-seven dentin discs prepared from extracted human molars were collected. Nine kinds of drugs were investigated with three dentin discs in each group. These nine drugs included two anti-bacterial drugs (ampicillin sodium and clindamycin phosphate), two corticosteroids (betamethasone sodium phosphate and hydrocortisone sodium succinate), three non-steroidal anti-inflammatory drugs (NSAIDs, piroxicam, lysine acetylsalicylate, and diclofenac sodium), and two natural extracts with anti-inflammatory effect (Ginsenoside Rg1 and Hinokitol). The drugs were introduced to the transwell dentin disc tube model and the 4-hour cumulative release of the drug was detected and recorded by UV-visible spectroscopy. RESULTS: We found that ampicilin sodium had better dentin permeability than clindamycin phosphate. Betamethasone sodium phosphate revealed better dentin permeability than hydrocortisone sodium succinate. Lysine acetylsalicylate showed the best dentin permeability among the three NSAIDs. Ginsenoside Rg1 had the best dentin permeability among the nine drugs tested. However, Hinokitiol could not penetrate the dentin disc after 4 h. CONCLUSION: Regarding the dentin permeability, Ginsenoside Rg1 is the best among the seven anti-inflammatory drugs tested and ampicilin sodium is the better one between the two anti-bacterial drugs tested. Therefore, these two drugs may have high potential for treating exposed dentinal tubule diseases.

Trigeminocardiac reflex during non-surgical root canal treatment of teeth with irreversible pulpitis.

BACKGROUND/PURPOSE: Trigeminocardiac reflex (TCR) is a unique clinical incident of acute change in hemodynamic balance, which may lead to hypotension, bradycardia, and even clinical crisis. Up to date, no study so far considers the impact of non-surgical root canal treatment (NSRCT) of irreversible pulpitis teeth under either local infiltration or block anesthesia on hemodynamic change possibly related to TCR. METHODS: This study enrolled 111 patients with 138 irreversible pulpitis teeth that were treated by two sessions of NSRCT. The first session involved mainly the removal of vital pulp tissue with the direct stimulation of the dental branches of the trigeminal nerve, and the second session included the root canal enlargement and debridement with minimal disturbance to the dental branches of the trigeminal nerve. Vital signs mainly the blood pressure were recorded during both NSRCT sessions. RESULTS: The incidences of NSRCT patients with MABP decrease ≧10%, ≧15%, or ≧20% were all significantly higher in the first NSRCT session than in the second NSRCT session (all the P-values < 0.001). In the first NSRCT session, the incidence of patients with MABP decrease ≧10% was significantly associated with tooth type. For both upper and lower teeth, the patients with premolars treated by NSRCR had significantly higher incidences of MABP decrease ≧10% than those with either anterior or molar teeth treated by NSRCR (all the P-values < 0.05). CONCLUSION: We conclude that vital pulp extirpation may lead to a substantial drop in patient's blood pressure possibly related to TCR.

Blood pressure reduction in patients with irreversible pulpitis teeth treated by non-surgical root canal treatment.

BACKGROUND/PURPOSE: The hypotension in patients during non-surgical root canal treatment (NSRCT) has not yet investigated. This study aimed to assess the mean systolic blood pressure (MSBP), mean diastolic blood pressure (MDBP), and mean arterial blood pressure (MABP) reduction percentages in patients with irreversible pulpitis teeth treated by NSRCT. MATERIALS AND METHODS: We prospectively recruited 111 patients with a total of 138 irreversible pulpitis teeth. All patients underwent two NSRCT sessions. The first NSRCT session involved mainly the removal of vital pulp tissue with the direct stimulation of the dental branches of the trigeminal nerve, and the second NSRCT session included the root canal debridement and enlargement with minimal disturbance to the dental nerves. The blood pressure of each patient was recorded before and during both NSRCT sessions. RESULTS: There were significantly higher reduction percentages of MSBP, MDBP, and MABP in the first NSRCT session than in the second NSRCT session for all treated patients (all the P-values < 0.001). If the patients were divided into 2 or more groups according to the clinical variables including the patients' gender, age, tooth type, and anesthesia type, we also found significantly higher reduction percentages of MSBP, MDBP, and MABP in the first NSRCT session than in the second NSRCT session for all treated patients except for patients below 40 years of age and for patients with lower anterior teeth treated (all the P-values < 0.05). CONCLUSION: The decrease in blood pressure in patients receiving vital pulpal extirpation is a relatively common phenomenon.