RESUMO
OBJECTIVE: To observe the clinical effect of a modified Simiao Tang (Modified Decoction of Four Wonderful Drugs) for gouty arthritis and its influence on uric acid in blood. METHODS: 120 cases of gouty arthritis were randomly divided into the treatment group and control group with 60 cases in each group. Modified Simiao Tang (MST) was orally administered to the patients in the treatment group and allopurinol tablet was orally administered to the patients in the control group. The clinical effects of two groups were evaluated after one-week treatment and uric acid (UA) and C-reactive protein (CRP) levels in blood were determined after 1-month treatment. RESULTS: The total effective rate in the treatment group was significantly higher than in the control group, 86.7% vs. 68.3% (P < 0.01). And the treatment group was also significantly better than the control group in decreasing UA and CRP (P < 0.05 or P < 0.01). CONCLUSIONS: MST can significantly improve the symptoms and signs of gouty arthritis and decrease the levels of UA and CRP. It is good for gouty arthritis.
