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1.
Neural Netw ; 123: 305-316, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31896462

RESUMO

The efforts devoted to manually increasing the width and depth of convolutional neural network (CNN) usually require a large amount of time and expertise. It has stimulated a rising demand of neural architecture search (NAS) over these years. However, most popular NAS approaches solely optimize for low prediction error without penalizing high structure complexity. To this end, this paper proposes MOPSO/D-Net, a CNN architecture search method with multiobjective particle swarm optimization based on decomposition (MOPSO/D). The main goal is to reformulate NAS as a multiobjective evolutionary optimization problem, where the optimal architecture is learned by minimizing two conflicting objectives, namely the error rate of classification and number of parameters of the network. Along with the hybrid binary encoding and adaptive penalty-based boundary intersection, an improved MOPSO/D is further proposed to solve the formulated multiobjective NAS and provide diverse tradeoff solutions. Experimental studies verify the effectiveness of MOPSO/D-Net compared with current manual and automated CNN generation methods. The proposed algorithm achieves impressive classification performance with a small number of parameters on each of two benchmark datasets, particularly, 0.4% error rate with 0.16M params on MNIST and 5.88% error rate with 8.1M params on CIFAR-10, respectively.


Assuntos
Redes Neurais de Computação , Simulação por Computador , Processamento de Imagem Assistida por Computador/métodos , Processamento de Imagem Assistida por Computador/normas
2.
BMC Bioinformatics ; 20(Suppl 22): 715, 2019 Dec 30.
Artigo em Inglês | MEDLINE | ID: mdl-31888444

RESUMO

BACKGROUND: The main goal of successful gene selection for microarray data is to find compact and predictive gene subsets which could improve the accuracy. Though a large pool of available methods exists, selecting the optimal gene subset for accurate classification is still very challenging for the diagnosis and treatment of cancer. RESULTS: To obtain the most predictive genes subsets without filtering out critical genes, a gene selection method based on least absolute shrinkage and selection operator (LASSO) and an improved binary particle swarm optimization (BPSO) is proposed in this paper. To avoid overfitting of LASSO, the initial gene pool is divided into clusters based on their structure. LASSO is then employed to select high predictive genes and further calculate the contribution value which indicates the genes' sensitivity to samples' classes. With the second-level gene pool established by double filter strategy, the BPSO encoding the contribution information obtained from LASSO is improved to perform gene selection. Moreover, from the perspective of the bit change probability, a new mapping function is defined to guide the updating of the particle to select the more predictive genes in the improved BPSO. CONCLUSIONS: With the compact gene pool obtained by double filter strategies, the improved BPSO could select the optimal gene subsets with high probability. The experimental results on several public microarray data with extreme learning machine verify the effectiveness of the proposed method compared to the relevant methods.


Assuntos
Algoritmos , Genes Neoplásicos , Análise de Sequência com Séries de Oligonucleotídeos/métodos , Bases de Dados Genéticas , Regulação Neoplásica da Expressão Gênica , Humanos , Aprendizado de Máquina , Neoplasias/genética , Probabilidade
3.
Artigo em Inglês | MEDLINE | ID: mdl-28182545

RESUMO

Traditional gene selection methods for microarray data mainly considered the features' relevance by evaluating their utility for achieving accurate predication or exploiting data variance and distribution, and the selected genes were usually poorly explicable. To improve the interpretability of the selected genes as well as prediction accuracy, an improved gene selection method based on binary particle swarm optimization (BPSO) and prior information is proposed in this paper. In the proposed method, BPSO encoding gene-to-class sensitivity (GCS) information is used to perform gene selection. The gene-to-class sensitivity information, extracted from the samples by extreme learning machine (ELM), is encoded into the selection process in four aspects: initializing particles, updating the particles, modifying maximum velocity, and adopting mutation operation adaptively. Constrained by the gene-to-class sensitivity information, the new method can select functional gene subsets which are significantly sensitive to the samples' classes. With the few discriminative genes selected by the proposed method, ELM, K-nearest neighbor and support vector machine classifiers achieve much high prediction accuracy on five public microarray data, which in turn verifies the efficiency and effectiveness of the proposed gene selection method.


Assuntos
Algoritmos , Biomimética/métodos , Perfilação da Expressão Gênica/métodos , Modelos Biológicos , Análise de Sequência com Séries de Oligonucleotídeos/métodos , Máquina de Vetores de Suporte , Simulação por Computador , Aglomeração , Modelos Estatísticos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
4.
PLoS One ; 11(11): e0165803, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27835638

RESUMO

For ensemble learning, how to select and combine the candidate classifiers are two key issues which influence the performance of the ensemble system dramatically. Random vector functional link networks (RVFL) without direct input-to-output links is one of suitable base-classifiers for ensemble systems because of its fast learning speed, simple structure and good generalization performance. In this paper, to obtain a more compact ensemble system with improved convergence performance, an improved ensemble of RVFL based on attractive and repulsive particle swarm optimization (ARPSO) with double optimization strategy is proposed. In the proposed method, ARPSO is applied to select and combine the candidate RVFL. As for using ARPSO to select the optimal base RVFL, ARPSO considers both the convergence accuracy on the validation data and the diversity of the candidate ensemble system to build the RVFL ensembles. In the process of combining RVFL, the ensemble weights corresponding to the base RVFL are initialized by the minimum norm least-square method and then further optimized by ARPSO. Finally, a few redundant RVFL is pruned, and thus the more compact ensemble of RVFL is obtained. Moreover, in this paper, theoretical analysis and justification on how to prune the base classifiers on classification problem is presented, and a simple and practically feasible strategy for pruning redundant base classifiers on both classification and regression problems is proposed. Since the double optimization is performed on the basis of the single optimization, the ensemble of RVFL built by the proposed method outperforms that built by some single optimization methods. Experiment results on function approximation and classification problems verify that the proposed method could improve its convergence accuracy as well as reduce the complexity of the ensemble system.


Assuntos
Algoritmos , Aprendizado de Máquina , Redes Neurais de Computação , Reconhecimento Automatizado de Padrão/estatística & dados numéricos , Neoplasias Encefálicas/química , Diabetes Mellitus/metabolismo , Humanos , Pulmão/química , Vinho/análise
5.
PLoS One ; 9(5): e97530, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24844313

RESUMO

To obtain predictive genes with lower redundancy and better interpretability, a hybrid gene selection method encoding prior information is proposed in this paper. To begin with, the prior information referred to as gene-to-class sensitivity (GCS) of all genes from microarray data is exploited by a single hidden layered feedforward neural network (SLFN). Then, to select more representative and lower redundant genes, all genes are grouped into some clusters by K-means method, and some low sensitive genes are filtered out according to their GCS values. Finally, a modified binary particle swarm optimization (BPSO) encoding the GCS information is proposed to perform further gene selection from the remainder genes. For considering the GCS information, the proposed method selects those genes highly correlated to sample classes. Thus, the low redundant gene subsets obtained by the proposed method also contribute to improve classification accuracy on microarray data. The experiments results on some open microarray data verify the effectiveness and efficiency of the proposed approach.


Assuntos
Redes Neurais de Computação , Análise de Sequência com Séries de Oligonucleotídeos/métodos , Software , Animais , Arabidopsis , Humanos
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