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OBJECTIVES: Gingivitis is one of the most prevalent plaque-initiated dental diseases globally. It is challenging to maintain satisfactory plaque control without continuous professional advice. Artificial intelligence may be used to provide automated visual plaque control advice based on intraoral photographs. METHODS: Frontal view intraoral photographs fulfilling selection criteria were collected. Along the gingival margin, the gingival conditions of individual sites were labelled as healthy, diseased, or questionable. Photographs were randomly assigned as training or validation datasets. Training datasets were input into a novel artificial intelligence system and its accuracy in detection of gingivitis including sensitivity, specificity, and mean intersection-over-union were analysed using validation dataset. The accuracy was reported according to STARD-2015 statement. RESULTS: A total of 567 intraoral photographs were collected and labelled, of which 80% were used for training and 20% for validation. Regarding training datasets, there were total 113,745,208 pixels with 9,270,413; 5,711,027; and 4,596,612 pixels were labelled as healthy, diseased, and questionable respectively. Regarding validation datasets, there were 28,319,607 pixels with 1,732,031; 1,866,104; and 1,116,493 pixels were labelled as healthy, diseased, and questionable, respectively. AI correctly predicted 1,114,623 healthy and 1,183,718 diseased pixels with sensitivity of 0.92 and specificity of 0.94. The mean intersection-over-union of the system was 0.60 and above the commonly accepted threshold of 0.50. CONCLUSIONS: Artificial intelligence could identify specific sites with and without gingival inflammation, with high sensitivity and high specificity that are on par with visual examination by human dentist. This system may be used for monitoring of the effectiveness of patients' plaque control.
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Placa Dentária , Gengivite , Humanos , Inteligência Artificial , Gengivite/diagnósticoRESUMO
Objective. Accurate and automatic segmentation of medical images is crucial for improving the efficiency of disease diagnosis and making treatment plans. Although methods based on convolutional neural networks have achieved excellent results in numerous segmentation tasks of medical images, they still suffer from challenges including drastic scale variations of lesions, blurred boundaries of lesions and class imbalance. Our objective is to design a segmentation framework named multi-scale contextual semantic enhancement network (3D MCSE-Net) to address the above problems.Approach. The 3D MCSE-Net mainly consists of a multi-scale context pyramid fusion module (MCPFM), a triple feature adaptive enhancement module (TFAEM), and an asymmetric class correction loss (ACCL) function. Specifically, the MCPFM resolves the problem of unreliable predictions due to variable morphology and drastic scale variations of lesions by capturing the multi-scale global context of feature maps. Subsequently, the TFAEM overcomes the problem of blurred boundaries of lesions caused by the infiltrating growth and complex context of lesions by adaptively recalibrating and enhancing the multi-dimensional feature representation of suspicious regions. Moreover, the ACCL alleviates class imbalances by adjusting asy mmetric correction coefficient and weighting factor.Main results. Our method is evaluated on the nasopharyngeal cancer tumor segmentation (NPCTS) dataset, the public dataset of the MICCAI 2017 liver tumor segmentation (LiTS) challenge and the 3D image reconstruction for comparison of algorithm and DataBase (3Dircadb) dataset to verify its effectiveness and generalizability. The experimental results show the proposed components all have unique strengths and exhibit mutually reinforcing properties. More importantly, the proposed 3D MCSE-Net outperforms previous state-of-the-art methods for tumor segmentation on the NPCTS, LiTS and 3Dircadb dataset.Significance. Our method addresses the effects of drastic scale variations of lesions, blurred boundaries of lesions and class imbalance, and improves tumors segmentation accuracy, which facilitates clinical medical diagnosis and treatment planning.
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Neoplasias Hepáticas , Neoplasias Nasofaríngeas , Humanos , Processamento de Imagem Assistida por Computador/métodos , Semântica , Imageamento Tridimensional/métodos , Redes Neurais de ComputaçãoRESUMO
PURPOSE: To assist physicians in the diagnosis and treatment planning of tumor, a robust and automatic liver and tumor segmentation method is highly demanded in the clinical practice. Recently, numerous researchers have improved the segmentation accuracy of liver and tumor by introducing multiscale contextual information and attention mechanism. However, this tends to introduce more training parameters and suffer from a heavier computational burden. In addition, the tumor has various sizes, shapes, locations, and numbers, which is the main reason for the poor accuracy of automatic segmentation. Although current loss functions can improve the learning ability of the model for hard samples to a certain extent, these loss functions are difficult to optimize the segmentation effect of small tumor regions when the large tumor regions in the sample are in the majority. METHODS: We propose a Liver and Tumor Segmentation Network (LiTS-Net) framework. First, the Shift-Channel Attention Module (S-CAM) is designed to model the feature interdependencies in adjacent channels and does not require additional training parameters. Second, the Weighted-Region (WR) loss function is proposed to emphasize the weight of small tumors in dense tumor regions and reduce the weight of easily segmented samples. Moreover, the Multiple 3D Inception Encoder Units (MEU) is adopted to capture the multiscale contextual information for better segmentation of liver and tumor. RESULTS: Efficacy of the LiTS-Net is demonstrated through the public dataset of MICCAI 2017 Liver Tumor Segmentation (LiTS) challenge, with Dice per case of 96.9 % ${\bf \%}$ and 75.1 % ${\bf \%}$ , respectively. For the 3D Image Reconstruction for Comparison of Algorithm and DataBase (3Dircadb), Dices are 96.47 % ${\bf \%}$ for the liver and 74.54 % ${\bf \%}$ for tumor segmentation. The proposed LiTS-Net outperforms existing state-of-the-art networks. CONCLUSIONS: We demonstrated the effectiveness of LiTS-Net and its core components for liver and tumor segmentation. The S-CAM is designed to model the feature interdependencies in the adjacent channels, which is characterized by no need to add additional training parameters. Meanwhile, we conduct an in-depth study of the feature shift proportion of adjacent channels to determine the optimal shift proportion. In addition, the WR loss function can implicitly learn the weights among regions without the need to manually specify the weights. In dense tumor segmentation tasks, WR aims to enhance the weights of small tumor regions and alleviate the problem that small tumor segmentation is difficult to optimize further when large tumor regions occupy the majority. Last but not least, our proposed method outperforms other state-of-the-art methods on both the LiTS dataset and the 3Dircadb dataset.
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Fígado , Neoplasias , Humanos , Fígado/diagnóstico por imagemRESUMO
Aiming at the high cost of data labeling and ignoring the internal relevance of features in existing trademark retrieval methods, this paper proposes an unsupervised trademark retrieval method based on attention mechanism. In the proposed method, the instance discrimination framework is adopted and a lightweight attention mechanism is introduced to allocate a more reasonable learning weight to key features. With an unsupervised way, this proposed method can obtain good feature representation of trademarks and improve the performance of trademark retrieval. Extensive comparative experiments on the METU trademark dataset are conducted. The experimental results show that the proposed method is significantly better than traditional trademark retrieval methods and most existing supervised learning methods. The proposed method obtained a smaller value of NAR (Normalized Average Rank) at 0.051, which verifies the effectiveness of the proposed method in trademark retrieval.
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As a new machine learning approach, the extreme learning machine (ELM) has received much attention due to its good performance. However, when directly applied to hyperspectral image (HSI) classification, the recognition rate is low. This is because ELM does not use spatial information, which is very important for HSI classification. In view of this, this paper proposes a new framework for the spectral-spatial classification of HSI by combining ELM with loopy belief propagation (LBP). The original ELM is linear, and the nonlinear ELMs (or Kernel ELMs) are an improvement of linear ELM (LELM). However, based on lots of experiments and much analysis, it is found that the LELM is a better choice than nonlinear ELM for the spectral-spatial classification of HSI. Furthermore, we exploit the marginal probability distribution that uses the whole information in the HSI and learns such a distribution using the LBP. The proposed method not only maintains the fast speed of ELM, but also greatly improves the accuracy of classification. The experimental results in the well-known HSI data sets, Indian Pines, and Pavia University, demonstrate the good performance of the proposed method.
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In ultrasound elastography, tissue axial strains are obtained through the differentiation of measured axial displacements. However, during the measurement process, the displacement signals are often contaminated with de-correlation noise caused by changes in the speckle pattern in the tissue. Thus, the application of the gradient operator on the displacement signals results in the presence of amplified noise in the axial strains, which severely obscures the useful information. The use of an effective denoising scheme is therefore imperative. In this paper, a method based on a two-stage consecutive filtering approach is proposed for the accurate estimation of axial strains. The presented method considers a cascaded system of a frequency filter and a time window, which are both designed such that the overall system operates optimally in a mean square error sense. Experimentation on simulated signals shows that the two-stage scheme employed in this study has good potential as a denoising method for ultrasound elastograms.