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Objective:To observe adjuvant curative effect and adverse reactions of montelukast in the treatment of children with bronchial asthma and its effect on recurrence. Methods:Totally 180 cases of children with bronchial asthma were randomly divided in-to the control group and the observation group with 90 ones in each. The control group was treated with oxygen and budesonide terbutal-ine inhalation, intravenous methylprednisolone sodium succinate and the other conventional treatment methods, and the observation group was additionally treated with montelukast sodium tablets 5 mg, po, qd. The treatment course was three months, and then expira-tory dyspnea, disappearance time of asthma and wheeze and adverse drug reactions in the two groups were evaluated. After 3-6-month follow-up, the recurrence was compared between the two groups as well. Results: The disappearance time of dyspnea, asthma and wheeze in the observation group was shorter than that in the control group (P<0. 05), the total effective rate in the observation group was 96. 67%, which was significantly higher than that in the control group (73. 33%, P<0. 05). The mean follow-up duration was (5. 1 ± 0. 3) months, and the recurrence rate was 8. 51% in the observation group, which was significantly lower than that in the con-trol group (31. 43%, P<0. 05). During the treatment, no significant adverse drug reaction was appeared in the two groups. Conclu-sion:The conventional drug treatment combined with montelukast can rapidly improve the clinical symptoms and reduce recurrence with promising safety, which is worthy of clinical application.
RESUMO
Objective To screen the relative risk and protective factors of children patients with asthma after capillary bronchiolitis.Methods The clinical and follow-up data of 220 children patients with capillary bronchiolitis were collected.Sex,treatment method,immunization vaccination,idiosyncrasy,feeding way,family history were investigated and analyzed.The risk factrs of asthma were screened.Results Univariate analysis showed that the incidence of asthma between different genders had no significant difference (P ＞0.05).The asthma incidence in patients with BCG vaccination on time and large-dose immunoglobulin treatment were lower than those in patients without BCG vaccination on time and large-dose immunoglobulin treatnent (P＜ 0.01 ).The asthma incidence in patients with idiosyncrasy,family history was significantly higher than that in patients without idiosyncrasy,family history( P ＜ 0.05 ).The asthma incidence in patients with obesity was higher than that in other children (P ＜ 0.05).The asthma incidence in patients with more than 4 months breast feeding was lower than that in patients with other feeding ways (P ＜ 0.05 ).Multi-factors regression analysis showed that family history,obesity,idiosyncrasy were the risk factors of asthua,and large-dose immunoglobulin treatment,BCG vaccination on time,breast feeding ＞ 4 months were the protective factors.Conclusions Family history,idiosyncrasy,obesity are the risk factors of asthma in children patients with capillary bronchiolitis,and should be focused on olservation.Immunoglobulin treatment and procedural BCG vaccination are the protective factors to reduce the asthma incidence.They are worthy of application especially in children with risk factors.
RESUMO
Objective To evaluate the efficacy of the combination interventional oviduct recanalization with traditional chinese medicine for infertile women with oviduct obstruction.Methods 38 cases with 76 oviduct obstruction were treated with FTC-900 oviduct recanalization apparatus guided with DSA,the apparatus was supplied by COOK company,before recanalization,assisted with side fornix vaginae and enema with traditional chinese medicine.Results Of 76 obstructive oviduct,71 oviduct were recanalization,the successful rates of recanalization were 93.4%;Of 38 infertile women ,25 cases become pregnant,the pregnant rates were 67.3%;Of 13 unsuccessful cases,8 cases turn out re-obstructived.Conclusion Combination interventional oviduct recanalization with traditional chinese medicine for infertile women with oviduct is a simple,safe,and more effective method,it has a high successful rates than either method solely,should be spreaded.
