Assuntos
Complexo de Carney/diagnóstico , Complexo de Carney/complicações , Criança , Subunidade RIalfa da Proteína Quinase Dependente de AMP Cíclico/genética , Diagnóstico Diferencial , Feminino , Humanos , Melanose/etiologia , Melanose/patologia , Mutação , Doenças Raras/complicações , Doenças Raras/diagnósticoRESUMO
Linear IgA bullous dermatosis (LAD) is an autoimmune, chronic bullous disease affecting primarily young children and adults. Studies on LAD are relatively sparse and from Scandinavia we could only find a few case reports. Therefore we decided to conduct a retrospective investigation of patients seen at our department since 1972. A total of 23 patients were identified; 7 children (F:M ratio 0.75) and 16 adults (F:M ratio 0.78). Mean age at disease onset in the two age groups were 2.7 and 56.8 years. Estimated incidence rate in our region: 0.67 per million per year. The most commonly used treatment modalities were corticosteroids, dapsone and sulphapyridine.
Assuntos
Dermatose Linear Bolhosa por IgA/epidemiologia , Adulto , Idade de Início , Idoso , Anti-Infecciosos/uso terapêutico , Pré-Escolar , Dapsona/uso terapêutico , Dinamarca/epidemiologia , Feminino , Glucocorticoides/uso terapêutico , Humanos , Incidência , Lactente , Dermatose Linear Bolhosa por IgA/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Prednisona/uso terapêutico , Estudos Retrospectivos , Sulfapiridina/uso terapêutico , Adulto JovemRESUMO
Topical glucocorticoids are the most commonly used drugs for treating a number of acute and chronic inflammatory diseases of the skin and the mucous membranes. Prolonged use of superpotent and potent topical glucocorticoids is related to an increased risk of developing severe side effects. In this case we describe the development of clinical signs of Cushing's syndrome in a 26-year-old woman, after continued daily application of potent topical glucocorticoid in the oral cavity.
