[On the question of a diurnal rhythm of the arterial oxygen tension (pO2a) (author's transl)]. / Zur Frage einer Tagesrhythmik des arteriellen Ruhe-pO2a.

In connection to our clinical examination of the so-called "Oxygen-Multistep-Therapy" (02-MT) was to clear, if the pO2a could be affected with a diurnal rhythm over the daytime between 7 a.m. and 5 p.m. The results, which were found at 66 healthy persons of different age and sex show an independence of the pO2 measured values from the daytime. Further, the action of Finalgon upon the earlap, and the variation of pO2a in dependence on age and sex were established, and a correlation between the arterial blood pressure and pO2a is discussed.

[Preliminary results of a pilot study on the optimisation and clinical examination of the "oxygen-multistep-therapy (O2Mt)" (author's transl)]. / Zwischenresultate einer Pilotstudie zur Optimierung und klinischen Prüfung der "Sauerstoff-Mehrschritt-Therapie (O2MT)".

It is reported about the preliminary results of a first clinical examination of O2MT in 46 patients. The "regeneration effect of O2MT" (v. Ardenne) is represented as an increase of resting values of arterial oxygen tension (PO2a), which demonstrable in about 2/3 of the patients. This effect continues more than 3 months after the end of O2MT. It is succeeded by "prophylactic and therapeutic effects, which were discussed as an improvement of cardiorespiratory and cardiovascular efficiency. The O2MT is suggested as a new treatment-method in premorbidities, who evolved out a "latent hypoxemia", especially for the use of preventive-treatment and gerontology-therapy.

[beta-glucuronidase activity in human tumors of the lung and of the mammary gland (author's transl)]. / beta-Glucuronidase-Aktivität in Bronchus- und Mammatumoren des Menschen.

The intratumoral activity of beta-Glucuronidase (total and free) was determined in surgical specimens of malignant tumors of the lung (N equal to 20) and of the breast (N equal to 15) from patients. A free beta-Glucuronidase-activity from about 90 mU per g tissue was found but there was no difference between both tumor types, and the beta-Glucuronidase-activity, as it seems, is not dependent on histological characteristics of the tumors. The findings are discussed under the view of the key function of the lysosomal enzymes in the concept of the "Cancer-Multistep-Therapy" by M. von Ardenne.

[Clinical examination of the conception '86 of "Canoer Multistep-Therapie" (CMT) by M. v. Ardene. First communication: the standard, the control-parameters, and the course of therapy (author's transl)]. / Klinische Prüfung des Krebs-Mehrschritt-Therapie-(KMT)-Konzepts '74 nach M. v. Ardenne. I. Mitteilung. Therapiestandard, Therapieüberwachungsparameter und Therapieverlauf

It is reported about the clinical testing of the "Cancer Multistep Therapy" (CMT) by M. von Ardenne (CMT Concept '74). It was made in 1974/75 on 42 tumour-patients. At first we demonstrate in this publication clinical and paraclinical findings, which may be relevant for the therapy-standard, but the results of the therapy-efficiency will be given later. On the base of findings and observations we verify a program-true employment of the CMT Concept '74 and we demonstrate the pathophysiological reaction-patterns in connection with the longterm-hyperglycemia (glucose-utilization, spontaneous hyperthermy with tachycardia, spontaneous leukocytosis with typical deviations in the hematogram). These reaction-patterns are described particularly as "general adaptation syndrome" (Selye). Further we give an assessment of compatibility, tolerableness, and practicability of the CMT.