Hydrodynamic interactions hinder transport of flow-driven colloidal particles.

The flow-driven transport of interacting micron-sized particles occurs in many soft matter systems spanning from the translocation of proteins to moving emulsions in microfluidic devices. Here we combine experiments and theory to investigate the collective transport properties of colloidal particles along a rotating ring of optical traps. In the corotating reference frame, the particles are driven by a vortex flow of the surrounding fluid. When increasing the depth of the optical potential, we observe a jamming behavior that manifests itself in a strong reduction of the current with increasing particle density. We show that this jamming is caused by hydrodynamic interactions that enhance the energetic barriers between the optical traps. This leads to a transition from an over- to an under-critical tilting of the potential in the corotating frame. Based on analytical considerations, the enhancement effect is estimated to increase with increasing particle size or decreasing radius of the ring of traps. Measurements for different ring radii and Stokesian dynamics simulations for corresponding particle sizes confirm this. The enhancement of potential barriers in the flow-driven system is contrasted to the reduction of barriers in a force-driven one. This diverse behavior demonstrates that hydrodynamic interactions can have a very different impact on the collective dynamics of many-body systems. Applications to soft matter and biological systems require careful consideration of the driving mechanism and of the role of hydrodynamic interactions.

Hydrodynamic Interactions Can Induce Jamming in Flow-Driven Systems.

Hydrodynamic interactions between fluid-dispersed particles are ubiquitous in soft matter and biological systems and they give rise to intriguing collective phenomena. While it was reported that these interactions can facilitate force-driven particle motion over energetic barriers, here we show the opposite effect in a flow-driven system, i.e., that hydrodynamic interactions hinder transport across barriers. We demonstrate this result by combining experiments and theory. In the experiments, we drive colloidal particles using rotating optical traps, thus creating a vortex flow in the corotating reference frame. We observe a jamminglike decrease of particle currents with density for large barriers between traps. The theoretical model shows that this jamming arises from hydrodynamic interactions between the particles. The impact of hydrodynamic interactions is reversed compared to force-driven motion, suggesting that our findings are a generic feature of flow-driven transport.

Single-file transport in periodic potentials: The Brownian asymmetric simple exclusion process.

Single-file Brownian motion in periodic structures is an important process in nature and technology, which becomes increasingly amenable for experimental investigation under controlled conditions. To explore and understand generic features of this motion, the Brownian asymmetric simple exclusion process (BASEP) was recently introduced. The BASEP refers to diffusion models where hard spheres are driven by a constant drag force through a periodic potential. Here we derive general properties of the rich collective dynamics in the BASEP. Average currents in the steady state change dramatically with the particle size and density. For an open system coupled to particle reservoirs, extremal current principles predict various nonequilibrium phases, which we verify by Brownian dynamics simulations. For general pair interactions we discuss connections to single-file transport by traveling-wave potentials and prove the impossibility of current reversals in systems driven by a constant drag and by traveling waves.

Brownian Asymmetric Simple Exclusion Process.

We study the driven Brownian motion of hard rods in a one-dimensional cosine potential with a large amplitude compared to the thermal energy. In a closed system, we find surprising features of the steady-state current in dependence of the particle density. The form of the current-density relation changes greatly with the particle size and can exhibit both a local maximum and minimum. The changes are caused by an interplay of a barrier reduction, blocking, and exchange symmetry effect. The latter leads to a current equal to that of noninteracting particles for a particle size commensurate with the period length of the cosine potential. For an open system coupled to particle reservoirs, we predict five different phases of nonequilibrium steady states to occur. Our results show that the particle size can be of crucial importance for nonequilibrium phase transitions in driven systems. Possible experiments for demonstrating our findings are pointed out.

Stress-stress fluctuation formula for elastic constants in the NPT ensemble.

Several fluctuation formulas are available for calculating elastic constants from equilibrium correlation functions in computer simulations, but the ones available for simulations at constant pressure exhibit slow convergence properties and cannot be used for the determination of local elastic constants. To overcome these drawbacks, we derive a stress-stress fluctuation formula in the NPT ensemble based on known expressions in the NVT ensemble. We validate the formula in the NPT ensemble by calculating elastic constants for the simple nearest-neighbor Lennard-Jones crystal and by comparing the results with those obtained in the NVT ensemble. For both local and bulk elastic constants we find an excellent agreement between the simulated data in the two ensembles. To demonstrate the usefulness of the formula, we apply it to determine the elastic constants of a simulated lipid bilayer.