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1.
J Dev Orig Health Dis ; 12(2): 335-342, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-32468978

RESUMO

Although prenatal exposure to high ambient temperatures were reported to be associated with preterm birth, limited research assessed the impact of weather-related extreme heat events (EHE) on birthweight, particularly by trimester. We, therefore, investigated the impact of prenatal EHE on birthweight among term babies (tLBW) by trimester and birthweight percentile. We conducted a population-based case-control study on singleton live births at 38-42 gestational weeks in New York State (NYS) by linking weather data with NYS birth certificates. A total of 22,615 cases were identified as birthweight <2500 gram, and a random sample of 139,168 normal birthweight controls was included. EHE was defined as three consecutive days with the maximum temperatures of ≥32.2 °C/90 °F (EHE90) and two consecutive days of temperatures ≥97th percentile (EHE97) based on the distribution of the maximum temperature for the season and region. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) with multivariable unconditional logistic regression, controlling for confounders. Overall exposure to EHE97 for 2 d was associated with tLBW (OR 1.05; 95% CI 1.02, 1.09); however, the strongest associations were only observed in the first trimester for both heat indicators, especially when exposure was ≥3 d (ORs ranged: 1.06-1.13). EHE in the first trimester was associated with significant reduction in mean birthweight from 26.78 gram (EHE90) to 36.25 gram (EHE97), which mainly affected the 40th and 60th birthweight percentiles. Findings revealed associations between multiple heat indicators and tLBW, where the impact was consistently strongest in the first trimester.


Assuntos
Peso ao Nascer , Calor Extremo/efeitos adversos , Recém-Nascido de Baixo Peso/crescimento & desenvolvimento , Nascimento Prematuro/epidemiologia , Tempo (Meteorologia) , Adulto , Estudos de Casos e Controles , Feminino , Humanos , Recém-Nascido , Masculino , New York/epidemiologia , Gravidez , Nascimento Prematuro/etiologia
2.
Birth Defects Res ; 112(16): 1273-1286, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32696579

RESUMO

BACKGROUND: While the maternal risk factors on congenital heart defects (CHDs) have often been assessed, paternal contribution to CHDs, especially the joint effects of paternal risk factors on CHDs remain unknown. This study examined the major impacts of paternal alcohol consumption and its interaction (on multiplicative and additive scales) with paternal socioeconomic status (SES) and environmental exposures on CHDs in China. METHODS: A population-based case-control study involving 4,726 singleton CHDs cases and 4,726 controls (without any malformation and matched on hospital, gender, and gestational age) was conducted in Guangdong, China, 2004-2014. Information on parental demographics, behavioral patterns, disease/medication, and environmental exposures (3 months before pregnancy) was collected through face-to-face interviews. Conditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) while controlling for all parental factors. RESULTS: Paternal alcohol consumption was associated with an increased OR of CHDs (adjusted OR = 2.87, 95% CI: 2.25-3.65). Additionally, paternal smoking, industry occupation, organic solvent contact, virus infection and antibiotic use, living in rural areas, low household income, and migrant status were significantly associated with CHDs (ORs ranged: 1.42-4.44). Significant additive or multiplicative interactions were observed between paternal alcohol consumption and paternal smoking, industrial occupation, and low income on any CHDs (interaction contrast ratio [ICR] = 4.72, 95% CI: 0.96-8.47] and septal defects (ICRs ranged from 2.04 to 2.79, p < .05). CONCLUSIONS: Paternal alcohol consumption and multiple paternal factors were significantly associated with CHDs in China. Paternal smoking and low SES factors modified paternal alcohol consumption-CHDs relationships. Further studies are needed to confirm these findings.


Assuntos
Cardiopatias Congênitas , Consumo de Bebidas Alcoólicas/efeitos adversos , Estudos de Casos e Controles , Exposição Ambiental , Feminino , Cardiopatias Congênitas/epidemiologia , Cardiopatias Congênitas/etiologia , Humanos , Gravidez , Classe Social
3.
Indoor Air ; 30(3): 544-552, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-31883404

RESUMO

Over half of schools surveyed in the United States reported one environmental problem affecting Indoor Air Quality. This study investigated environmental concerns in schools, teacher-reported symptoms, and performance in relation to thermal environment, lighting, and noise conditions in New York State classrooms. This cross-sectional study consisted of telephone surveys among teachers from 428 NYS public schools. Survey contents included teacher demographics, employment characteristics, and environmental factors. Unconditional logistic regression analyses were used to estimate odds ratios (OR) of health symptoms for classroom conditions including thermal environment, lighting, and acoustics. Although too dry, too hot, or cold were major thermal concerns, 78% of the teachers reported that they cannot control temperature through thermostat. Over 50% of NYS teachers reported almost all health symptoms worsening during workdays. We found the top five most common health symptoms reported by NYS teachers are all allergy-related symptoms. Additionally, all extreme thermal factors were significantly associated with work-related symptoms in teachers. "Too dry" had the highest risk for allergic symptoms (OR: 2.49, 95% CI: 2.01-3.10), and then followed by any noise (OR: 2.46, 95% CI: 1.80-3.36) associated with voice-related health, and "lighting too dim" (OR: 2.38, 95% CI: 1.77-3.19). Future studies are needed to confirm these findings.


Assuntos
Iluminação , Exposição Ocupacional , Professores Escolares , Temperatura , Acústica , Poluição do Ar em Ambientes Fechados , Estudos Transversais , Humanos , Doenças Profissionais , Instituições Acadêmicas
4.
Disaster Med Public Health Prep ; 13(1): 28-32, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30841951

RESUMO

OBJECTIVE: Investigate short- and long-term effects of Superstorm Sandy on multiple morbidities among the elderly. METHODS: We examined emergency department visits; outpatient visits; and hospital admissions for cardiovascular disease (CVD), respiratory disease, and injury among residents residing in 8 affected counties immediately, 4 months, and 12 months following Superstorm Sandy. Control groups were defined as visits/admissions during the identical time window in the 5 years before (2007-2011) and 1 year after (2013-2014) the storm in affected and nonaffected counties in New York. We performed Poisson regression to test whether there was an association of increased visits/admissions for periods following Superstorm Sandy while controlling for covariates. RESULTS: We found that the risk for CVD, respiratory disease, and injury visits/admissions was more than twice as high immediately, 4 months, and 12 months after the storm than it was in the control periods. Women were at greater risk at all time periods for CVD (risk ratio [RR], 2.04) and respiratory disease (RRs: 1.89 to 1.92). Whites had higher risk for CVD, respiratory disease, and injury than other racial groups during each period. CONCLUSION: We observed increases in CVD, respiratory disease, and injury up to a year following Superstorm Sandy. Findings demonstrate the need to incorporate short- and long-term health effects into public health recovery. (Disaster Med Public Health Preparedness. 2019;13:28-32).


Assuntos
Tempestades Ciclônicas/estatística & dados numéricos , Serviço Hospitalar de Emergência/estatística & dados numéricos , Geriatria/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Serviço Hospitalar de Emergência/organização & administração , Feminino , Geriatria/métodos , Humanos , Masculino , Medicaid/estatística & dados numéricos , Medicare/estatística & dados numéricos , New York/epidemiologia , Estados Unidos , Populações Vulneráveis/estatística & dados numéricos
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