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1.
Ocul Immunol Inflamm ; 28(4): 659-664, 2020 May 18.
Artigo em Inglês | MEDLINE | ID: mdl-31268742

RESUMO

Cytomegalovirus (CMV) retinitis is an opportunistic infection classically described in patients with acquired immune deficiency syndrome and other immune-compromising situations. As the diagnosis is based on clinical findings, classic retinal imaging montages have been a useful tool, being able to detect up to 140º of the retina. Since ultra-widefield (UWF) imaging systems have been available we can now detect more area of peripheral lesions in the diagnosis and follow-up of patients' response to antiviral treatment. We present a series of cases in which UWF was used as the main tool for diagnosis, monitoring, and management in patients with CMV retinitis.In all the cases presented, UWF imaging with fundus autofluorescence was able to capture peripheral CMV retinitis areas and discern active from inactive lesions. This, added to the comfort of use, seem to make UWF imaging a useful tool to detect changes in the follow-up of patients with CMV retinitis.


Assuntos
Antivirais/uso terapêutico , Retinite por Citomegalovirus/diagnóstico , Infecções Oculares Virais/diagnóstico , Angiofluoresceinografia/métodos , Retina/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Retinite por Citomegalovirus/tratamento farmacológico , Infecções Oculares Virais/tratamento farmacológico , Feminino , Seguimentos , Fundo de Olho , Humanos , Masculino , Pessoa de Meia-Idade
2.
Int Ophthalmol ; 39(11): 2661-2665, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30852735

RESUMO

PURPOSE: The authors report a case of Purtscher's retinopathy whose optical coherence tomography angiography (OCT-A) analysis allows us to better understand the vascular network of the optic disk. METHODS: Case report. RESULTS: A 75-year-old man presented with vision loss in his left eye (LE) after chest compression. The best-corrected visual acuity (BCVA) in the LE was 20/200, and the anterior segment showed a relative afferent pupillary defect. Dilated fundus examination revealed white peripapillary retinal patches and macular hemorrhage. The OCT scan showed edema and hyper-reflectivity of the inner retinal layers at macular level. In turn, OCTA evidenced capillary dropout in both macular retinal plexus, though with preservation of the radial peripapillary capillaries (RPC) and choriocapillary layer. At 9 months, BCVA was 20/20 associated with persistence macular ischemia but unaffected RPC. CONCLUSION: In conclusion, this case suggests that the RPC does not depend exclusively on retinal capillaries as there was a reversible damage after a microvascular retinal disorder such as Purtscher's retinopathy. Possibly, the contribution from short posterior ciliary arteries ensures proper vascularization as choriocapillary layer also remained unaffected. Furthermore, OCTA is considered a useful tool that affords better assessment of RPC than FA.


Assuntos
Capilares/patologia , Artérias Ciliares/patologia , Angiofluoresceinografia/métodos , Disco Óptico/irrigação sanguínea , Doenças Retinianas/diagnóstico , Tomografia de Coerência Óptica/métodos , Acuidade Visual , Idoso , Fundo de Olho , Humanos , Masculino
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