Neuroepigenomics: Resources, Obstacles, and Opportunities.

Long-lived post-mitotic cells, such as the majority of human neurons, must respond effectively to ongoing changes in neuronal stimulation or microenvironmental cues through transcriptional and epigenomic regulation of gene expression. The role of epigenomic regulation in neuronal function is of fundamental interest to the neuroscience community, as these types of studies have transformed our understanding of gene regulation in post-mitotic cells. This perspective article highlights many of the resources available to researchers interested in neuroepigenomic investigations and discusses some of the current obstacles and opportunities in neuroepigenomics.

Electronic aids for daily living.

Electronic aids to daily living (EADLs) are devices that facilitate the operation of electrical appliances in a given environment for a person with a severe physical disability. These specialized devices can provide tremendous psychological and functional benefits to someone with a severe disability, their family members and caregivers. This article provides an overview of the utility, functionality, access, acquisition, and evaluation of EADLs. It also highlights challenges in obtaining and measuring the benefits of these devices.