Effects of school soccer training on the health and fitness of obese children / Efeitos do treinamento de futebol escolar sobre a saúde e a aptidão física de crianças obesas / Efectos del entrenamiento de fútbol escolar en la salud y la aptitud física de niños obesos

ABSTRACT Introduction Based on the representative data reflecting the level of physical development and athletic quality, such as the "National Physical Health Test for Students", it is shown that the physical health status of adolescents and children in China is decreasing annually, and the trend of obesity is gradually increasing. Objective Analyze and study the effect of training on the physical fitness of obese children aged 12 to 14 through school soccer training. Methods The effect of school soccer training on the health and physical fitness of obese children aged 12-14 years was studied, and conclusions were drawn by the literature method, experimental method, mathematical statistical method, and logical analysis method. Forty-eight screened obese children were randomly assigned to the experimental and control groups, 24 in each group. The experimental group underwent 12 weeks of soccer training, and the control group underwent 12 weeks of no training control. The subjects' body composition and flexibility quality indices were measured post-intervention. Results The visceral fat index, body fat rate, and muscle rate of boys and girls progressed expressively, with a significant difference (P <0.05). Muscle weight is also known as lean body weight, with an expressive increase in muscle tone. In comparison, the increase in fat weight and muscle ratio in boys was expressively higher than in girls. Conclusion Regular long-term school soccer training can increase mobility in obese children, increase physical flexibility, and help promote physical health and prevent injury. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.

RESUMO Introdução Com base nos dados representativos que refletem o nível de desenvolvimento físico e qualidade atlética, como o "Teste Nacional de Saúde Física para Estudantes", é demonstrado que o estado de saúde física de adolescentes e crianças na China está diminuindo anualmente, e que a tendência de obesidade está aumentando gradualmente. Objetivo Analisar e estudar o efeito do treinamento na aptidão física de crianças obesas entre 12 a 14 anos de idade através do treinamento de futebol escolar. Métodos O efeito do treinamento de futebol escolar sobre a saúde e a aptidão física de crianças obesas de 12-14 anos de idade foi estudado, e as conclusões foram tiradas pelo método da bibliografia, método experimental, método estatístico matemático e método de análise lógica. Quarenta e oito crianças obesas submetidas a triagem foram designadas aleatoriamente aos grupos experimentais e de controle, 24 em cada grupo. O grupo experimental passou por 12 semanas de treinamento de futebol e o grupo de controle passou por 12 semanas sem controle de treinamento. A composição corporal e os índices de qualidade da flexibilidade dos sujeitos foram medidos antes e depois da intervenção. Resultados Resultados: O índice de gordura visceral, a taxa de gordura corporal e a taxa muscular de meninos e meninas progrediu expressivamente, com diferença significativa (P <0,05). O peso de musculatura também é conhecido como peso corporal magro, com um aumento expressivo do tônus muscular. Em comparação, o aumento do peso de gordura e da taxa muscular nos meninos foi expressivamente maior do que o encontrado nas meninas. Conclusão O treinamento regular de futebol escolar de longo prazo pode aumentar a mobilidade das crianças obesas, aumentar a flexibilidade física e ajudar a promover a saúde física além de prevenir lesões. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.

RESUMEN Introducción A partir de los datos representativos que reflejan el nivel de desarrollo físico y la calidad atlética, como la "Prueba Nacional de Salud Física para Estudiantes", se demuestra que el estado de salud física de los adolescentes y niños en China disminuye anualmente, y la tendencia de la obesidad aumenta gradualmente. Objetivo Analizar y estudiar el efecto del entrenamiento sobre la forma física de niños obesos de entre 12 y 14 años mediante el entrenamiento de fútbol escolar. Métodos Se estudió el efecto del entrenamiento de fútbol escolar en la salud y la forma física de niños obesos de 12 a 14 años, y se extrajeron conclusiones mediante el método bibliográfico, el método experimental, el método estadístico matemático y el método de análisis lógico. Cuarenta y ocho niños obesos examinados fueron asignados aleatoriamente a los grupos experimental y de control, 24 en cada grupo. El grupo experimental se sometió a 12 semanas de entrenamiento futbolístico y el grupo de control, a 12 semanas sin entrenamiento. Se midieron la composición corporal y los índices de calidad de la flexibilidad de los sujetos antes y después de la intervención. Resultados El índice de grasa visceral, el índice de grasa corporal y el índice muscular de niños y niñas progresaron expresivamente con diferencias significativas (P <0,05). El peso muscular también se conoce como peso corporal magro, con un aumento expresivo del tono muscular. En comparación, el aumento del peso graso y de la tasa muscular en los chicos fue expresivamente superior al observado en las chicas. Conclusión El entrenamiento regular de fútbol escolar a largo plazo puede aumentar la movilidad en niños obesos, incrementar la flexibilidad física y ayudar a promover la salud física, además de prevenir lesiones. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.

Value of anti-p53 antibody as a biomarker for hepatocellular carcinoma: Evidence from a meta-analysis.

INTRODUCTION: The incidence of hepatocellular carcinoma (HCC) ranks sixth in the world, but its mortality is the third highest due to the lack of early diagnostic markers. Nowadays, the increase of autoantibody levels has been found in many cancers, and many studies have begun to pay attention to the detection of anti-p53 antibodies in HCC. The purpose of this study is to quantitatively and comprehensively analyze the potential diagnostic value of anti-p53 autoantibodies in HCC METHODS:: English articles up to November 2019 were collected. The overall sensitivity and specificity were calculated. Besides, the positive likelihood ratio, negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and summary receiver operating characteristic curves of the overall diagnostic accuracy of anti-p53 antibody were calculated by STATA software. Finally, according to the heterogeneity of the results, the subgroup analysis, and the publication bias were performed. RESULTS: A total of 16 eligible studies were incorporated into this meta-analysis, including 1323 patients with HCC and 1896 control. The pooled sensitivity was 0.28(0.17-0.41) and specificity was 0.98 (0.95-0.99). The pooled DOR was 10.44 (6.31-17.29) and the pooled NLR was 0.74 (0.63-0.86). The area under ROC curve of symmetrical ROC was 0.840. CONCLUSIONS: The anti-p53 antibody has a high specificity for HCC, but the low sensitivity is not perfect and would limit the clinical application. The anti-p53 antibody would help rule out HCC but not help rule in HCC for early diagnosis. Whether combined as a diagnostic panel with other biomarkers or laboratory tests may prove useful requires further study.

Microbial reduction of Fe(III)-bearing clay minerals in the presence of humic acids.

Both Fe(III)-bearing clay minerals and humic acids (HAs) are abundant in the soils and sediments. Previous studies have shown that bioreduction of structural Fe(III) in clay minerals could be accelerated by adding anthraquinone compound as a redox-active surrogate of HAs. However, a quinoid analogue could not reflect the adsorption and complexation properties of HA, and little is known about the effects of real HAs at environmental concentration on bioreduction of clay minerals. Here, it was shown that 10-200 mg l-1 of natural or artificially synthesized HAs could effectively stimulate the bioreduction rate and extent of Fe(III) in both iron-rich nontronite NAu-2 and iron-deficient montmorillonite SWy-2. After adsorption to NAu-2, electron-transfer activities of different HA fractions were compared. Additionally, Fe(II) complexation by HAs also contributed to improvement of clay-Fe(III) bioreduction. Spectrosopic and morphological analyses suggested that HA addition accelerated the transformation of NAu-2 to illite, silica and siderite after reductive dissolution.

Esophageal squamous cell carcinoma and ALDH2 and ADH1B polymorphisms in Chinese females.

AIM: Alcohol dehydrogenase-IB (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) are the key enzymes for elimination of ethanol and acetaldehyde, the latter being an established animal carcinogen produced after drinking. In this study, we aimed to evaluate the contribution of ADH1B and ALDH2 polymorphisms to the risk of esophageal squamous cell (ESCC) in Chinese females. METHODS: A total of 81 pathologically-proven female ESCC cases and 162 female controls were recruited from the Affiliated Hospital of Medical College of Armed Police Forces of PRC in China. ADH1B and ALDH2 polymorphisms were genotyped using PCR-CTPP. RESULTS: Compared with those with ADH1B*2/*2, individuals with ADH2*1/*2 and ADH2*1/*1 had 1.47 and 2.36-fold, respectively, increased risk of developing ESCC (95%CI=0.84-2.58, 95%CI=1.14-5.79) after adjusting for alcohol consumption and other covariates. Significantly increased risk was also noted among subjects with ALDH2*1/*2 (adjusted OR=3.24, 95%CI=1.45-5.36), when compared to those with ALDH2*1/*1. Risk was greater in heavy drinking females carrying ADH1B *1/*1 or ALDH2*1/*2 genotypes compared to those with ADH1B*2 and ALDH2*1/*1. Moreover, we found a significant trend of ESCC risk with alcoholic consumption in women with ALDH2*1/*2. CONCLUSION: Chinese women with ADH1B *1/*1 or ALDH2*1/*2 have elevated risk of ESCC similarly to men. Women with inactive ADH1B and ALDH2 should reduce drinking and increase their intake of vegetable and fruit to prevent development of esophageal cancer.