[Pollution Characteristics and Source Apportionment of Heavy Metals in Farmland Soils Around the Gangue Heap of Coal Mine Based on APCS-MLR and PMF Receptor Model].

To analyze the pollution characteristics and source apportionment of heavy metal pollution in soil of farmland surrounding the Gangue Heap of Coal Mine in Nanchuan, Chongqing, the Nemerow pollution index and Muller index were used. Meanwhile, to investigate the sources and contribution rate of heavy metals in the soil, absolute principal component score-multiple linear regression receptor modeling (APCS-MLR) and positive matrix factorization (PMF) were employed. The results showed higher amounts of Cd, Hg, As, Pb, Cr, Cu, Ni, and Zn in the downstream area than those in the upstream area, and only Cu, Ni, and Zn showed significantly higher amounts in the downstream area than those in upstream area (P<0.05). The comprehensive Nemerow pollution index was as follows:downstream area (1.22)>upstream area (0.95), and the degree of heavy metal pollution was:Cd>Cu>Hg, As, Pb, Cr, Ni, and Zn. The Muller pollution index showed:Cd>As>Cu=Hg>Ni>Zn=Cr>Pb. The pollution source analysis showed that Cu, Ni, and Zn were mainly affected by mining activities such as long-term accumulation of the gangue heap of coal mine, with the contribution rates of APCS-MLR being 49.8%, 94.5%, and 73.2%, respectively. Additionally, PMF contribution rates were 62.8%, 62.2%, and 63.1%, respectively. Cd, Hg, and As were mainly affected by agricultural activities and transportation activities, with APCS-MLR contribution rates of 49.8%, 94.5%, and 73.2% and PMF contribution rates of 62.8%, 62.2%, and 63.1%, respectively. Further, Pb and Cr were mainly affected by natural factors, with APCS-MLR contribution rates of 66.4% and 94.7% and PMF contribution rates of 42.7% and 47.7%, respectively. The results of source analysis were basically consistent between the APCS-MLR and PMF receptor models.

Clinicopathological characteristics and prognosis of breast cancer patients with lung cancer: A study based on 19,807 breast cancer patients.

This study was conducted to investigate the clinicopathological characteristics and prognosis of breast cancer and lung cancer (BC-LC) and provide a theoretical basis for the diagnosis and treatment of BC-LC in clinical work. A retrospective study was conducted on breast cancer (BC) patients in our center from September 2009 to November 2020. The patients were divided into the BC-LC group and the control group. The control group was matched with both, the age at diagnosis and the time of surgery (±1 year). The clinicopathological factors, overall survival (OS), and hazard ratios (HRs) were evaluated by SPSS. A total of 19,807 BC patients were identified, among whom 124 (0.6%) had lung cancer (LC). Larger BC tumor was the only independent risk factor (OR=2.454, p<0.001) for development of LC in BC patients. We found inferior survival in patients with synchronous versus metachronous BC-LC (p=0.008). We also identified combined with hypertension (HR=3.917, p=0.003) was an independent prognostic factor for inferior OS. Therefore, BC patients with larger tumors need close follow-up. Effective prevention and active treatment of hypertension can improve the OS of BC-LC patients.

[A study of three different procedures for avulsion fracture of tibial intercondylar eminence].

OBJECTIVE: To observe the clinical outcomes and differences among three surgical procedures for avulsion fracture of tibial intercondylar eminence. METHODS: From October 1995 to October 2005, 3 different procedures had been performed on 49 patients, which included open reduction and internal fixation (Group A, n = 17), arthroscopic reduction and internal fixation( Group B, n = 19) and limited open reduction and internal fixation assisted with arthroscopy (Group C, n = 13). All patients were followed up for 1 to 10 years (average 4. 6 years). RESULTS: For the 3 groups, normal extension function were 35.5%, 16.0% and 38.0%, mild abnormal 35.5%, 11.0% and 23.0%, moderate abnormal 29.0%, 47.0% and 31.0%; and severe abnormal were 0,26.0% and 8.0%. Normal flexion were 82.0%, 78.0% and 84.0%, mild abnormal 12.0%, 11.0% and 8.0%, moderate abnormal 6.0%, 11.0% and 8.0%. The positive rate of Lachman's or anterior drawer test were 35.0%, 45.0% and 38.0%; McIntoshi test were 11.0%, 16.0% and 13.0% respectively for 3 groups. Lysholm' scale were average 98.6, 97.3 and 98.2; Tegner' scale were 6.6, 6.4 and 6.7. KT-2000 showed that anterior translation of tibial were 6.9, 7.1 and 6.6 mm; side to side difference were 11.4, 1.7 and 1.5 mm, except that statistically significant differences were found in extension function between group A and group B (P = 0.02). There were no any statistically significant differences in other aspects. CONCLUSION: Limited open and properly over reduction and three dimensional as well as strong internal fixation assisted with arthroscopy should been attempted for the treatment of avulsion fracture of tibial intercondylar eminence.