1.
J Org Chem
; 64(22): 8263-8266, 1999 Oct 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11674746
RESUMO
Cylindricine A (1) and cylindricine B (2) have been synthesized in 11 steps and 19% overall yield. The key reaction involves the addition of an organocopper species to a bicyclic vinylogous amide, which provides complete stereocontrol over the installation of the hexyl side chain.