[Retroperitoneal laparoscopic decortication and adrenalectomy for the therapy of adrenal cysts].

OBJECTIVE: To summarize the clinical characteristics of adrenal cysts and compare the therapeutic results of two different laparoscopic surgical techniques. METHODS: Sixteen patients of adrenal cysts were summarized retrospectively from May 2005 to June 2012. Their clinical manifestations, pathological features, therapeutic effects and prognosis were analyzed. There were 7 males and 9 females aged 39.4 (25-68) years.Eight patients were symptomatic and the others were identified incidentally. They underwent laparoscopic surgery through retroperitoneal space, including adrenalectomy (n = 11) and decortication (n = 5). RESULTS: All were confirmed as adrenal cysts by postoperative pathological examination.It accounted for around 7.5% of adrenal disease treated surgically at our department cutaneous. The diagnostic accuracy of computed tomography and magnetic resonance imaging was 11/16 and 3/3 respectively. The mean diameter of cyst was 5.3 (1-14) cm and no apparent endocrine abnormalities were found. The symptoms of 7/8 patients were relieved after a mean 48 months follow-up.No recurrence was found in this cohort. The average operative duration and estimated volume of blood loss were significantly less in laparoscopic decortication group ( (48 ± 10) min, (16 ± 11) ml) than laparoscopic adrenalectomy group ((74 ± 21) min, (34 ± 30) ml) . CONCLUSIONS: Laparoscopic surgery is an effective procedure for the treatment of adrenal cysts. And retroperitoneal laparoscopic decortication may be preferred treatment option for large benign adrenal cysts.

Allium vegetables and risk of prostate cancer: evidence from 132,192 subjects.

OBJECTIVE: To evaluate the relationship between allium vegetable intake and risk of prostate cancer. METHODS: A systematic literature search up to May 2013 was carried out in PubMed, EMBASE, Scopus, Web of Science, Cochrane register, and Chinese National Knowledge Infrastructure (CNKI) databases, and the references of retrieved articles were also screened. The summary relative risks with 95% confidence interval for the highest versus the lowest intake of allium vegetables were calculated. Heterogeneity and publication bias were also evaluated. RESULTS: A total of nine epidemiological studies consisting of six case-control and three prospective cohort studies were included. We found a significantly decreased risk of prostate cancer for intake of allium vegetables (OR = 0.82, 95% CI 0.70, 0.97). Moreover, in the subgroup analysis stratified by allium vegetable types, significant associations were observed for garlic (OR = 0.77, 95% CI 0.64-0.91) but not onions (OR = 0.84, 95% CI 0.62-1.13). CONCLUSIONS: Allium vegetables, especially garlic intake, are related to decreased risk of prostate cancer. Because of the limited number of studies, further well-designed prospective studies are warranted to confirm the findings of our study.

[Hereditary tendency of varicocele].

OBJECTIVE: To investigate the hereditary tendency of varicocele. METHODS: We included in this study 112 varicocele patients, 117 direct male relatives of the patients, and 100 healthy men as controls. We compared the incidence of varicocele tween the direct relative group and the control group. RESULTS: The direct male relatives of the varicocele patients had a significantly higher incidence of varicocele than the healthy controls (36.8% vs 17%, P < 0.05). CONCLUSION: The increased incidence of varicocele in the direct male relatives of the patients indicated a hereditary tendency of the disease.

[Relationship of body mass index with cancer detection in prostate biopsy].

OBJECTIVE: To investigate the relationship of body mass index with cancer detection on prostate biopsy. METHODS: A total of 168 patients undergoing a prostate biopsy were divided into obese and non-obese groups by BMI ≥ 25 or < 25. Then the differences of prostate-specific antigen (PSA) level, prostate volume, prostate cancer detection rate and pathology result between two groups. RESULTS: The obese group had a higher rate of cancer detection than the non-obese group [67.1% (51/76) vs 48.9% (45/92), P < 0.05]. Logistics regression analysis showed that BMI ≥ 25 had a positive correlation with cancer detection on biopsy. CONCLUSION: Body mass index can raise the risk of prostate cancer on biopsy.