[Optimization for preparation technology of shangke jiefu lotion by orthogonal test].

OBJECTIVE: To optimize the preparation technology of Shangke Jiefu lotion. METHODS: The extraction process was optimized by orthogonal test, with water addition, extraction times and time used for extraction as factors of investigation. In refined process test, alcohol precipitation concentration, time, and the relative density of extract were studied. Each factor had three levels. The content of sophorcarpidine and the yield of dry extract were used as the evaluation indexes. The content of sophorcarpidine was determined by HPLC, and dry extract rates were determined by drying method. RESULTS: The best extraction condition was as follows: the amount of water was 10 times of the medicinal materials, the decoction duration was 2 h and for 3 times. The optimum purification process was: alcohol precipitation concentration was 50%, time was 15 hours, relative density of extract was 1.05 g/mL. CONCLUSION: The optimized preparation technology of Shangke Jiefu lotion is stable, feasible and convenient. It provides a theoretical basis for standardized production.

[Study on the flax seed enzymatic degumming process by central composite design and response surface method].

OBJECTIVE: To optimize extraction condition of degumming from flax seed by the response surface method. METHODS: The central composite design-response surface method selected the best technology and forecasting analysis with the ratio of material to liquid, sodium chloride dosage, soaks time as the independent variable and flax seed dry rubber weight for the dependent variable, through to the level of the independent variable multiple linear regression and binomial fitting. RESULTS: The optimum process condition was as follows: ratio of liquid to materials was 37:1, sodium chloride dosage was 2 g, soaks time was 120 min. CONCLUSION: The method is simple, reasonable, stable and predictability.