[Toxicological evaluation of the outgassing of tetrafluoroethylene-based thermostable polymeric materials during heating]. / Toksikologicheskaia otsenka gazovydeleniia termostoikikh polmernykh materialov na osnove tetraftorétilena pri ikh nagrevanii.

The purpose of this study was to investigate the composition and toxicity of fluoroplastic F-40 thermodestruction products at 300-500 degrees C and to identify the maximally allowable temperature for their safe use. When heated over 400 degrees C, the products of luoroplastic F-40 evolution included such compounds as hydrogen fluoride, fluro-organic compounds, carbon monoxide, formaldehyde. When heated at 500 degrees C, the thermodestruction products caused the highest mortality rate of mice. The pathogenesis and clinical development of fluoroplastic F-40 poisoning are primarily associated with fluoro-compounds. It is concluded that the temperature 300 degrees C is the maximum temperature at which tetrafluroethylene-based polymers can be used.

[Biochemical indices of the healthy human being in a hermetic chamber with periodically ionized air]. / Nekotorye biokhimicheskie pokazateli u zdorovogo cheloveka v usloviiakh germokamery s periodicheski ioniziruemym vozdukhom.

The content of 11-hydroxycorticosteroids, triglycerides and enzyme activity in blood as well as the content of 17-ketosteroids in urine of normal men kept for 16 days in an enclosure ventilated for 24--60 hours with bipolar ionized air (averaged unipolarity factor 1.58, concentration of positive ions 26--35 thous. cm-(3)) were measured. On DD 7--9 concentrations of 11-HOCS, triglycerides and 17-KS increased. This can be attributed to an activation of the hypophyseal-adrenal system in response to the enclosure effect. Further rapid return of the parameters to the normal may be associated with the cumulative effect of air ionization. This ionization at the doses used did not influence activities of creatine phosphokinase, aspartate aminotransferase and alphahydroxybutyrate dehydrogenase.

[Reactions of the adrenal cortex to immobilization stress in intact animals and against a background of hypokinesia]. / Ob osobennostiakh reaktsii kory nadpochechnikov na immobilizatsionnyi stress u intaktnykh zhivotnykh i na fone gipokinezii.

Morphological investigation of the rat adrenal cortex and corticosterone contents in the blood plasma demonstrated certain peculiarities in the adrenal reaction to the primary and repeated immobilization stress in intact animals and after hypokinesia. It has been stated that morphological manifestation to an acute stress reaction kinesia is less pronounced than at an analogous single effect. Investigation on corticosterone content in blood plasma revealed certain functional peculiarities in the adrenal cortex reactions in different variants of the experiments. Five hours after the beginning of the stress, corticosterone content was increased only at the initial immobilization, while at repeated stimulations during the same time it did not differ from the control. Changes in functional possibilities of the adrenal cortex in response to a repeated stimulation and in response to a new stimulation in animals previously adapted to another type of stress are discussed.