[Index of microcirculatory changes in experimental dehydration in animals]. / Ob indekse izmenenii mikrotsirkuliatsii pri éksperimental'nom obezbozhivanii zhivotnykh.

On the basis of morphokinetic synthesis principles the method of determination of summarizing criterion of microcirculatory system changes was developed. It consists of marked characteristics of changes of a number of the most important morphofunctional phenomena of each of this system compartments -- interstitial, lymphatic, blood and cellular -- with their successive summation to obtain the systemic microcirculation index. The experimental dehydration in rats being a model has shown that systemic microcirculatory index was 2 times as large in 3 days of dehydration, more than 3 times -- in 6 days, and 4, 5 times -- in 12 days. In the initial stage of the experiments maximal changes were found in interstitial compartment of the microcirculatory system. The intermediate period of dehydration differed by predominant changes of vascular compartment when the lymphatic phenomena were more evident than the hemomicrocirculatory ones. In the later stage of dehydration the cellular component changes of tissues and organs were predominant.

[Comparative evaluation of the adaptive mechanisms of the microcirculatory bed during dehydration]. / Sravnitel'naia otsenka mekhanizmov adaptatsii mikrotsirkuliatornogo rusla pri obezvozhivanii.

In total preparations of the white rat small intestine mesentery, impregnated with silver nitrate, as well as under conditions of vital microscopical observations at certain stages of alimentary experimental dehydration, analogous changes in the microcirculatory bed links have been demonstrated. Comparison of quantitative parameters in decreasing diameters of the microvessels, specific for dehydrated preparations has shown a great importance of these changes in the impregnated preparations at the expense of tissue condensation at their histological treatment. The advantages of a complex application of both methods for estimating dynamics of vascular, intervascular and extravascular changes are proved.

[Reactivity of the microcirculation bed of the small intestine mesentery in experimental dehydration in rats]. / Reaktivnost' mikrotsirkuliatornogo rusla bryzheiki tonkoi kishki pri éksperimental'noi degidratatsii u krys.

The state of mesenteric microcirculatory bed has been studied in male rats 3, 6 and 12 days after the beginning of alimentary dehydration. It has been revealed that vascular, intravascular and extravascular changes were of particular importance. Spastic reactions of arterioles and precapillary arterioles, the activation of arteriolo-venular shunting and the reduction in capillary circulation accompanied by diminution of all microvascular diameters were among the most marked vascular phenomena. The intravascular changes were represented by decreased blood flow rate, erythrocyte aggregation and leucocyte adhesion. The extravascular phenomena were characterized by the appearance of local hemorrhages.