[The reactivation of pulmonary tuberculosis after effective chemotherapy using rifampicin]. / Reaktivatsiia tuberkuleza legkikh posle éffektivnoi khimioterapii s primeneniem rifampitsina.

The authors present an analysis of dynamic five-year follow-up of 141 patients with freshly detected destructive pulmonary tuberculosis that received treatment with isoniaside and rifampicin in combination with other drugs. It was found that reactivation of pulmonary tuberculosis with the use of rifampicin is observed in 11 +/- 5% of patients and is accompanied by phenomena of not infrequently marked intoxication and chest symptoms and complaints. The importance of timing the main course of chemotherapy (not less than 12 months) and regular prophylactic autumn-spring course of treatment in the prophylaxis of reactivations of pulmonary tuberculosis.