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2.
J Nutr Metab ; 2014: 861659, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25505983

RESUMO

This randomized, controlled trial examined the effects of canned pineapple consumption on immunomodulation, nutritional status, and physical health of ninety-eight (98) school children with mean age of 8.44 ± 0.20. The study participants were divided into three groups: Group A (33) includes subjects who were not given canned pineapple, Group B (33) includes those who were given 140 g, and Group C (32) includes those given 280 g of canned pineapple for nine weeks. Each major group was further divided into two groups: normal (N) and underweight (U) based on 2007 WHO Growth Reference Standards. Sociodemographic, anthropometric, physical examination, dietary intake, hemoglobin level, and immunological data were analyzed. Results showed a decrease in incidence of viral and bacterial infections for both Group B and Group C (normal and underweight) after canned pineapple consumption. Granulocyte production increased by 0.77-26.61% for normal weight subjects and 14.95-34.55% for underweight. CD16+56 count augmented by 20.44-22.13% for normal weight and 3.57-15.89% for underweight subjects. Thus, intake of both one can (140 g) and two cans (280 g) of canned pineapple may shorten the duration and incidence of infection and may increase the production of granulocytes and CD16+56, but intake of two cans (280 g) demonstrated higher granulocyte and CD16+56 production. This trial is registered with Philippine Health Research Registry: PHRR140826-000225.

3.
Nutrition ; 25(9): 920-5, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19647623

RESUMO

OBJECTIVE: To determine if parenteral glutamine dipeptide supplementation given only in the preoperative period in malnourished patients after gastrointestinal surgery would sustain its effects into the first postoperative week, as shown by immune indices. METHODS: A prospective randomized study on malnourished adult patients for abdominal surgery was done where one group (n = 17) received preoperative glutamine supplementation (0.3 g . kg(-1) x d(-1)) for 5 d and the other (n = 17) had none. Both received isocaloric (30 kcal x kg(-1) x d(-1)) and isonitrogenous (1.5 g x kg(-1) x d(-1)) nutrition. Outcomes were 1) immune indices on admission (day 1), the day before surgery (day 2), and the seventh postoperative day (day 3); and 2) clinical outcomes were infection, wound complication, days in the intensive care unit, and mortality. Statistical tests were repeated samples analysis of variance, Friedman's test, Wilcoxon's test, and t test for individual comparison. RESULTS: The glutamine-supplemented group showed an increase in total white blood cells (from 8700 on day to 11 080 on day 2, P = 0.026), granulocytes (from 6177 on day 1 to 8568 on day 2, P = 0.039), and lymphocytes (from 1516 on day 1 to 1747 on day 2, P = 0.049). Significant decreases in glutamine-supplemented group values from day 2 to day 3 occurred in granulocytes, lymphocytes, and CD8, CD22, and CD19 cells. Clinical outcome was similar in both groups. Intake was adequate in both groups (preoperative 85% versus postoperative 82% computed) and the mean glutamine delivered was 18 g/d. CONCLUSION: Parenteral glutamine supplementation in the preoperative period resulted in increased white blood cell, granulocyte, and lymphocyte counts, which was not sustained in the first week of the postoperative period, when supplementation was discontinued before surgery.


Assuntos
Antígenos CD/sangue , Procedimentos Cirúrgicos do Sistema Digestório , Glutamina/farmacologia , Granulócitos/efeitos dos fármacos , Linfócitos/efeitos dos fármacos , Desnutrição/imunologia , Assistência Perioperatória/métodos , Abdome/cirurgia , Adulto , Cuidados Críticos , Suplementos Nutricionais , Dipeptídeos , Feminino , Granulócitos/metabolismo , Humanos , Infusões Intravenosas , Contagem de Leucócitos , Linfócitos/metabolismo , Masculino , Desnutrição/complicações , Pessoa de Meia-Idade , Cuidados Pós-Operatórios , Período Pós-Operatório , Estudos Prospectivos
4.
Obes Surg ; 17(1): 82-7, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17355773

RESUMO

BACKGROUND: Information on experience in bariatric surgery in the Asia-Pacific region is minimal: hence the need for more reports from this area. METHODS: The procedures of bariatric surgery and outcome as part of a weight management program in a tertiary care private hospital in the Philippines is reported from years 2002 to 2004. 50 patients were included, of which 60% underwent laparoscopic adjustable gastric banding (LAGB) and 40% Roux-en-Y gastric bypass (RYGBP). RESULTS: There were more females than males (64% vs 36%) with the mean age 38 +/- 13.1 years. Initial mean BMI was 46.2 kg/m(2), which decreased to 27.0 kg/m(2) in 1 year. Initial mean weight was 126.7 +/- 25.4 kg, of which the 1 year weight loss was 32.3 kg for the morbidly obese and 58.0 kg for the super obese. %EWL at 1 year was 30.2%. There was greater weight loss with RYGBP compared to LAGB at 1 year (43.5 kg vs 30.2 kg). There was no mortality, and early complications were: wound infection (2/50 or 4%), and 1/50 or 2% each for pneumonia, dehydration, gastritis, and leakage. Late complications were: band slippage (2/20 or 10%), stomal stenosis (1/20 or 5%), and ventral hernia (1/5 or 20%). CONCLUSION: Bariatric surgery is safe with a low complication rate and the outcome was similar to the reported data from Asia and the western world.


Assuntos
Cirurgia Bariátrica/estatística & dados numéricos , Obesidade Mórbida/cirurgia , Adolescente , Adulto , Idoso , Cirurgia Bariátrica/efeitos adversos , Índice de Massa Corporal , Feminino , Hospitais Privados , Humanos , Masculino , Pessoa de Meia-Idade , Filipinas , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento , Redução de Peso
5.
Nutrition ; 22(4): 345-9, 2006 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-16472978

RESUMO

OBJECTIVES: This study compared the computed nutrient requirements of geriatric patients under critical care with their actual intake within the first 3 d after admission to the intensive care unit (ICU) and determined the percentage of patients who achieved adequate intake. METHODS: Fifty-eight geriatric patients who were admitted to the ICU from September to December 2002 were prospectively enrolled. Recommended and actual calorie intakes per patient were recorded and mean amount of carbohydrate, protein, and fat consumed were calculated. Student's t test was used to compare actual with recommended nutrient intakes. RESULTS: Actual in relation to recommended nutrient intake was inadequate (41.5% on day 1 to 71.7% on day 3 for calories and 21.1% on day 1 to 24.3% on day 3 for protein, P < 0.001). Carbohydrate intake was low (falling from 61.9% on day 1 to 39.8% on day 3, P < 0.001) and fat intake was also low (increasing from 29.4% to 37.9% on day 3, P < 0.001). The percentage of patients who achieved adequate intake was 51.2% on day 1 and increased to 73.2% on day 3. CONCLUSIONS: The intake of geriatric patients in the ICU is low, with differences in actual and recommended intakes. Delivering what is recommended is still a goal to be realized in the ICU setting.


Assuntos
Cuidados Críticos/normas , Ingestão de Energia , Necessidades Nutricionais , Apoio Nutricional/métodos , Idoso , Idoso de 80 Anos ou mais , Índice de Massa Corporal , Carboidratos da Dieta/administração & dosagem , Gorduras na Dieta/administração & dosagem , Proteínas Alimentares/administração & dosagem , Feminino , Avaliação Geriátrica , Humanos , Unidades de Terapia Intensiva , Masculino , Pessoa de Meia-Idade , Avaliação Nutricional , Filipinas , Estudos Prospectivos
6.
Clin Nutr ; 25(1): 91-101, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16198450

RESUMO

BACKGROUND & AIMS: To improve hospital health care delivery by identifying malnutrition in all admitted patients and following up those identified to be malnourished and "at risk of developing malnutrition" a hospital nutrition support program based on the JCAHO system was initiated in 1999. Two major problems were encountered: first, the inability to perform a nutrition surveillance process due to failure by the staff to implement existing nutrition screening tools and second, the lack of awareness and support from the medical staff in this initiative. Two solutions were implemented in 2000: computerization of the nutrition screening and nutrition support process and synchronizing this with the whole nutrition support program. METHODS: A computer program was developed which performs BMI-based nutrition screening, produces lists of all malnourished patients, and computes the different formulas for either nutritional requirement or parenteral and/or enteral formulation. It also generates patient status reports based on encoded data from the nutrition support team, which prioritized these patients for management based on the data output. RESULTS: From 2000 to 2003, improvement was seen in these areas: entry of height and weight in the patient record increased from 30% to 90%; nutrition surveillance shows nutritional status distribution to be: normal (58%), underweight (9%), overweight (25%), and obese (8%), referrals to the nutrition support team based on the screen notification increased from 37% to 100%, patient coverage by nutrition support services increased from 7374 (38.8%) in 2000 to 11,369 (83%) in 2003, and critical care patients seen increased from 10% in 2000 to 99% in 2003. More improvement is needed in physician response to nutrition support recommendations, which still remains low (11.2-24%). CONCLUSIONS: Computerization helps to improve nutrition support delivery in the hospital, but more cooperation and support from the medical staff is still needed for better results.


Assuntos
Sistemas Computadorizados de Registros Médicos , Distúrbios Nutricionais/diagnóstico , Distúrbios Nutricionais/terapia , Apoio Nutricional/métodos , Recursos Humanos em Hospital/educação , Qualidade da Assistência à Saúde , Índice de Massa Corporal , Hospitalização , Humanos , Joint Commission on Accreditation of Healthcare Organizations , Programas de Rastreamento , Avaliação Nutricional , Necessidades Nutricionais , Estado Nutricional , Equipe de Assistência ao Paciente , Recursos Humanos em Hospital/normas , Filipinas , Resultado do Tratamento , Estados Unidos
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