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Pharmacopsychiatry ; 38(5): 220-1, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-16189749

RESUMO

A case of necrotizing enterocolitis in a 19-year old man treated for schizophrenic disorder, induced by a drug association involving clozapine and requiring surgical treatment, is presented. To our knowledge only few reports have described the occurrence of this complication with atypical antipsychotics. Evidence for linking this complication to clozapine was reinforced by the absence of any viral or bacterial infection. The authors present a review of similar cases, stress the potential hazards induced by such drug combinations and discuss supposed mechanisms of this enterocolitis.


Assuntos
Antipsicóticos/efeitos adversos , Clozapina/efeitos adversos , Enterocolite Necrosante/etiologia , Adulto , Antibacterianos/uso terapêutico , Creatina Quinase/sangue , Enterocolite Necrosante/sangue , Enterocolite Necrosante/tratamento farmacológico , Humanos , Masculino , Esquizofrenia/sangue , Esquizofrenia/tratamento farmacológico
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