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1.
Med Phys ; 29(4): 538-43, 2002 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11991125

RESUMO

The low dose rate CDC-type miniature cylindrical 137Cs sources are available, with one or three active beads, for use in source trains in automatic and manual afterloading systems for gynecological brachytherapy. Absolute dose rate distributions in water have been calculated around these sources using the Monte Carlo GEANT3 code and they are presented as conventional two-dimensional Cartesian lookup tables. The AAPM Task Group 43 formalism for dose calculation has been also applied. The dose rate constant obtained for the one bead source is lambda = 1.113 +/- 0.003cGyh(-1) U(-1), and the value for the three bead source is A= 1.103 +/- 0.003cGyh(-1) U(-1). Finally, for the treatment planning systems based on Sievert-type algorithms, the attenuation coefficients that best reproduce Monte Carlo dose rate distribution are given.


Assuntos
Braquiterapia/instrumentação , Braquiterapia/métodos , Radiometria/métodos , Ar , Algoritmos , Método de Monte Carlo , Radiometria/normas , Planejamento da Radioterapia Assistida por Computador
2.
Phys Med Biol ; 46(7): 2029-40, 2001 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-11474942

RESUMO

Basic dosimetric data for the Walstam CDC.K-type low dose rate 137Cs sources in water have been calculated using Monte Carlo techniques. These sources, CDC.K1 -K3 and CDC.K4, are widely used in a range of applicators and moulds for the treatment of intracavitary and superficial cancers. Our purpose is to improve existing data about these sources using the Monte Carlo simulation code GEANT3. Absolute dose rate distributions in water have been calculated around these sources and are presented as conventional 2D Cartesian look-up tables. Also the AAPM Task Group 43 formalism for dose calculation has been applied. The calculated dose rate constant for the CDC.K1-K3 source is A = 1.106 +/- 0.001 cGy h(-1) U(-1), and for the CDC.K4 source, A = 1.092 +/- 0.001 cGy h(-1) U(-1). The anisotropy of the sources are accurately studied and F(r, theta) tables are given. Also phi an(r) factors are presented. The radial dose functions are given as a polynomial fit to the calculated data up to 15 cm. Best-fit values of coefficients suitable for use in Sievert integral calculations have been derived.


Assuntos
Radioisótopos de Césio , Planejamento da Radioterapia Assistida por Computador/métodos , Algoritmos , Anisotropia , Humanos , Modelos Estatísticos , Método de Monte Carlo , Radiometria , Software
3.
Phys Med Biol ; 46(7): N169-174, 2001 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-11474943

RESUMO

The CSM3 137Cs type stainless-steel encapsulated source is widely used in manually afterloaded low dose rate brachytherapy. A specially asymmetric source, CSM3-a, has been designed by CIS Bio International (France) substituting the eyelet side seed with an inactive material in the CSM3 source. This modification has been done in order to allow a uniform dose level over the upper vaginal surface when this 'linear' source is inserted at the top of the dome vaginal applicators. In this study the Monte Carlo GEANT3 simulation code, incorporating the source geometry in detail, was used to investigate the dosimetric characteristics of this special CSM3-a 137Cs brachytherapy source. The absolute dose rate distribution in water around this source was calculated and is presented in the form of an along-away table. Comparison of Sievert integral type calculations with Monte Carlo results are discussed.


Assuntos
Braquiterapia/instrumentação , Braquiterapia/métodos , Radioisótopos de Césio , Radiometria/métodos , Algoritmos , Feminino , Humanos , Método de Monte Carlo , Neoplasias/radioterapia , Planejamento da Radioterapia Assistida por Computador/métodos , Vagina/efeitos da radiação
4.
Med Phys ; 28(4): 654-60, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11339763

RESUMO

The purpose of this study is to find fitted functional forms to the anisotropy function, F(r, theta), and the radial dose function, g(r), in order to characterize dose-rate distributions around all the high-intensity 192Ir sources currently in use. Dosimetry data are at present available as tables for: the microSelectron HDR ("classic" and "new" design models), the PDR source, and the VariSource HDR source, expressed in terms of the AAPM Task Group No. 43 recommendations. There is only one paper out which introduces a functional form to fit the anisotropy function, but only for symmetric sources with respect to the transverse axis. However, dosimetric data of the HDR and PDR sources mentioned above cannot be reproduced with these functional forms. In our study F(r,theta) and g(r) published data are fitted with functional forms in such a way that appropriate limits are reached for both functions and the maximum fit error approaches the data uncertainty. The average fit error is less than 1% in all cases. These functional forms make handling data easier within the treatment planning system, avoiding the use of tabulated data.


Assuntos
Irídio , Radioisótopos , Radiometria , Anisotropia , Modelos Estatísticos , Modelos Teóricos , Método de Monte Carlo
5.
Phys Med Biol ; 46(3): N79-90, 2001 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11277236

RESUMO

In this study a complete set of dosimetric data is presented for the high dose rate (HDR) source from Amersham used in the Buchler remote afterloading HDR unit. These data have been calculated by means of the Monte Carlo simulation code GEANT taking into account the detailed geometry of the source. Absolute dose rate distributions in water were calculated around this source and are presented as conventional 2D Cartesian look-up tables. All dosimetric quantities recommended by the AAPM Task Group 43 report have been calculated. Quantities determined are: dose rate constant, radial dose function, anisotropy function, anisotropy factor and anisotropy constant. The dose rate distributions of the Buchler HDR source are compared with those of other HDR sources used in brachytherapy, showing that the differences are large in zones near the long source axis due to oblique filtration. These Monte Carlo simulated data in water can be used for clinical applications.


Assuntos
Braquiterapia/instrumentação , Braquiterapia/métodos , Radioisótopos de Irídio , Anisotropia , Desenho de Equipamento , Método de Monte Carlo , Dosagem Radioterapêutica
6.
Med Phys ; 28(12): 2576-85, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11797963

RESUMO

In this study a complete set of dosimetric data for the Plus and 12i Gammamed PDR (pulsed dose rate) 192Ir sources is presented. These data have been calculated using the Monte Carlo simulation code GEANT3. Absolute dose rate distributions in water around these sources were calculated and are presented in form of conventional two dimensional (2D) Cartesian look-up tables. All dosimetric quantities recommended by the AAPM Task Group 43 report have been also calculated. These quantities are dose rate constant, radial dose function, anisotropy function and anisotropy factor. The dose rate distribution of the 12i source was compared with the corresponding data for the microselectron PDR source showing large differences between both sources.


Assuntos
Radioisótopos de Irídio/uso terapêutico , Radiometria/métodos , Ar , Anisotropia , Método de Monte Carlo , Aceleradores de Partículas , Água
7.
Med Phys ; 28(12): 2586-91, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11797964

RESUMO

In this study a complete set of dosimetric data for the GammaMed high dose rate (HDR) 12i and Plus 192Ir sources are presented. These data have been calculated by means of the Monte Carlo simulation code GEANT3. Absolute dose rate distributions in water are presented as conventional two dimensional (2D) Cartesian look-up tables, and in the TG43 formalism.


Assuntos
Braquiterapia/instrumentação , Radioisótopos de Irídio/uso terapêutico , Radiometria/métodos , Anisotropia , Fenômenos Biofísicos , Biofísica , Método de Monte Carlo , Água
8.
Med Phys ; 27(9): 2182-9, 2000 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-11011749

RESUMO

The purpose of this study is to calculate basic dosimetry data for a CSM11 low dose rate 137Cs source in water. This source is widely used in afterloadable dome cylinders designed to homogeneously irradiate the vaginal cuff alone or additional areas of the vagina in hysterectomized patients. In this study, the Monte Carlo simulation code GEANT, incorporating in detail source geometry, is used to investigate the dosimetric characteristics of the source. The calculated data were analyzed using a fitting procedure that is described in detail. Absolute dose rate distributions in water were calculated around this source and are presented as conventional 2D Cartesian lookup tables (classically along-away tables). Also, the dose calculation formalism endorsed by the Interstitial Collaborative Working Group and the AAPM Task Group 43 have been calculated. The calculated dose rate constant for this source is lambda = 1.096 +/- 0.002 cGy h(-1) U(-1). The anisotropy function results in about 50% deviations from isotropy at positions near the long axis of the source. The radial dose function is given as a polynomial that reproduces the calculated data up to 20 cm. Best-fit values of attenuation coefficients suitable for use in Sievert integral calculations have been derived.


Assuntos
Radioisótopos de Césio/uso terapêutico , Método de Monte Carlo , Radiometria/métodos , Ar , Humanos , Planejamento da Radioterapia Assistida por Computador , Água
9.
Phys Med Biol ; 45(7): 1841-9, 2000 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-10943922

RESUMO

In electron beam therapy, tissue overdose due to electrons backscattered from lead has been profusely studied. To quantify this dose enhancement effect, an electron backscatter factor (EBF) was defined as the ratio of dose at the tissue-inhomogeneity interface with and without the scatterer present. The dependence of the EBF on energy at the scatterer surface is not well known for energies lower than 3 MeV which is the most frequent clinical situation. In this work, we have done Monte Carlo calculations with the GEANT code to study EBF in lead at this energy range. The applicability of this code and the developed procedure for dose estimation has been experimentally verified. The dependence of the EBF on the beam energy incident on the scatterer has been studied for different nominal beam energies incident at the phantom's surface. The results show a trend of increase of EBF with the beam energy incident on the scatterer between 0.5 and 1.5 MeV, keeping practically constant above this energy up to 3 MeV. Backscattered electron energy spectra and depth dose curves in the 'up-stream' direction have been obtained at the various energies of the primary electron beam striking on the lead scatterer. The results of this work are compared with previously published data.


Assuntos
Elétrons/uso terapêutico , Chumbo , Radiometria/métodos , Planejamento da Radioterapia Assistida por Computador/métodos , Algoritmos , Simulação por Computador , Relação Dose-Resposta à Radiação , Método de Monte Carlo , Software
10.
Med Phys ; 27(1): 132-40, 2000 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-10659748

RESUMO

The Amersham CDCS-M-type 137Cs stainless-steel encapsulated source is widely used in low dose rate brachytherapy with manual afterloading. However there is a need for more accurate dosimetry data. In this study we present Monte Carlo calculations of absolute dose rate in water around this source using the Monte Carlo code GEANT, discuss dosimetric features of these data, and compare them with Krishnaswamy's results for 137Cs intracavitary sources. Dose rate distributions are presented in the form of along-away tables and in the TG43 formalism. Simulated absolute dose rate values can be used as benchmark data to verify the treatment planning system calculation results or directly as input data for treatment planning. Best-fit values of attenuation coefficients suitable for use in Sievert integral type calculations have been derived comparing dose rate distributions calculated using this algorithm with those obtained from Monte Carlo calculations.


Assuntos
Braquiterapia/métodos , Radioisótopos de Césio/administração & dosagem , Algoritmos , Fenômenos Biofísicos , Biofísica , Braquiterapia/estatística & dados numéricos , Radioisótopos de Césio/uso terapêutico , Simulação por Computador , Estudos de Avaliação como Assunto , Humanos , Método de Monte Carlo , Planejamento da Radioterapia Assistida por Computador , Água
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