RESUMO
BACKGROUND: The incidence of skin cancer continues to increase. However, little is known about the dermatosurgical characteristics of the patients. PATIENTS AND METHODS: In this single center, retrospective study, dermatosurgical reports of all patients treated because of basal cell carcinomas (BCC), squamous cell carcinomas (SCC), and malignant melanoma (MM) between 2004 and 2013 were analyzed. RESULTS: During the observed period, the number of operated BCC rose by a factor of 1.86 and the number of MM by a factor of 2.3. In comparison to BCC/MM, there was a disproportionately high increase of SCC by a factor of 4.02. The average age was 71.5 ± 13.4 years (minimum: 14 years; maximum: 104 years), whereupon a significant increase of male age and a significant decrease of female age occurred. Almost 70% of all tumors were located in the head and neck area. The nose was most commonly treated. CONCLUSIONS: During the last 10 years, the cohort of dermatosurgical patients changed in the tumor center. This should be verified in multicenter studies.
Assuntos
Institutos de Câncer/estatística & dados numéricos , Procedimentos Cirúrgicos Dermatológicos/estatística & dados numéricos , Neoplasias Cutâneas/epidemiologia , Neoplasias Cutâneas/cirurgia , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Alemanha/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores de Risco , Distribuição por Sexo , Adulto JovemRESUMO
BACKGROUND: Retarded cutaneous hypersensitivity to several antigens has been studied in human of different ages and in people older than 60 years a diminishment in response to tests measuring retarded hypersensitivity has been observed. OBJECTIVE: To determine the pattern of response to tests of retarded hypersensitivity in an apparently healthy sample of Cuban population resident at La Habana City, by application of a group of cutaneous tests with national antigens. MATERIAL AND METHODS: Intradermal tests were applied to 87 subjects (69 women and 18 men) between 60 and 89 years old, without frequent infection antecedents. All subjects were submitted to clinical history and analysis in order to discard diseases that may alter the study proposal. Response grade was determined by summing media of induration diameters, which was denominated total media punctuation. RESULTS: In all age groups total media punctuation was lightly higher in women, in both control and study groups, excepting age group of 80-89 years. CONCLUSION: By virtue of there are few indicators of health for old people, the group of tests proposed in this article may be a good predictive indicator of morbidity and mortality in old patients.
Assuntos
Hipersensibilidade Tardia/diagnóstico , Testes Cutâneos/métodos , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
La evaluación de algunos aspectos de la reacción inmunitaria en el anciano estresado fue la finalidad de este estudio que se realizó a 96 personas de la tercera edad. Los sujetos de estudio se dividieron por grupos de edades a partir de los 60 años, tomándose el grupo de edades a partir de los 60 años, tomándose el grupo de ancianos no estresados como grupo testigo. No hubo diferencias significativas en las concentraciones de inmunoglobulina A, G, M, en el seno de la población estudiada. Se encontraron elteraciones significativas en la prueba de formación de roseta espontánea del grupo estresado
Assuntos
Humanos , Idoso , Idoso/psicologia , Estresse Psicológico/imunologia , Estresse Psicológico/psicologiaRESUMO
La evaluación del estado inmunológico en trabajadores expuestos en razón de su trabajo al plomo fue el motivo de este estudio realizado a 14 trabajadores, los que fueron comparados con otros no expuestos, de edad y sexos similares (grupo control).La concentración media de plomo en sangre de la población expuesta fue de 46.9+- 2.3 ng/dl. No hubo diferencias significativas en las concentraciones del suero IgC, IgA e IgM entre las poblaciones estudiadas. Se comprobó la correlación entre la concentración de plomo en la sangre y los niveles de inmunoglobulinas G. Encontramos alteraciones significativas en las pruebas de formación de rosetas (R A y R E)
Assuntos
Humanos , Masculino , Adulto , Imunoglobulinas/imunologia , Chumbo/imunologia , Técnicas Imunológicas/instrumentação , Imunoglobulina A/análise , Imunoglobulina A/imunologia , Imunoglobulina G/análise , Imunoglobulina G/imunologia , Imunoglobulina M/análise , Imunoglobulina M/imunologia , Imunoglobulinas/análise , Chumbo/sangue , Medicina do TrabalhoRESUMO
The evaluation of immunological conditions of 14 workers occupationally exposed to lead and comparison of these results with those of a non-exposed control group with similar age and sex were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 ug/dl while in the control group it was 10.9 ug/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant diminishment in the formation of rosette in relation to the control group.
Assuntos
Indústria Química , Imunidade Celular/efeitos dos fármacos , Imunoglobulinas/sangue , Síndromes de Imunodeficiência/induzido quimicamente , Chumbo/efeitos adversos , Exposição Ocupacional , Adulto , Animais , Humanos , Deficiência de IgG/induzido quimicamente , Chumbo/sangue , Chumbo/farmacologia , Chumbo/toxicidade , Contagem de Leucócitos/efeitos dos fármacos , Ratos , Formação de Roseta , Linfócitos T/efeitos dos fármacosRESUMO
Se evaluó el estado inmunológico de 14 trabajadores expuestos por razones de su ocupación al plomo, los sujetos estudiados se compararon con otros no expuestos, de edad y sexo similares (grupo testigo). La concentración medida de plomo en la sangre de la población expuesta fue 46,9 ñ 2,3 µg/dl. No hubo diferencias significativas en las concentraciones del suero IgG, IgA e IgM entre las poblaciones estudiadas. Se comprobó la correlación entre la concentración de plomo en sangre y el inmunoglobulinas G
Assuntos
Humanos , Masculino , Adulto , Exposição Ambiental/efeitos adversos , Imunoglobulinas/imunologia , Chumbo/imunologia , Exposição Ambiental/análise , Imunoglobulinas/análise , Chumbo/sangue , Medicina do TrabalhoRESUMO
The evaluation of immunological conditions of 14 workers occupationally exposed to lead and the comparison of these results with those of a non-exposed control group with similar age and sex were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 micrograms/dl while in the control group it was 10.9 micrograms/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant decrease in the formation for rosette in relation to the control group.
Assuntos
Agamaglobulinemia/induzido quimicamente , Formação de Anticorpos/efeitos dos fármacos , Imunidade Celular/efeitos dos fármacos , Intoxicação por Chumbo/imunologia , Chumbo/farmacologia , Doenças Profissionais/imunologia , Adulto , Humanos , Chumbo/efeitos adversos , Chumbo/sangue , Masculino , Doenças Profissionais/induzido quimicamente , Exposição Ocupacional , Formação de RosetaRESUMO
The evaluation of immunological conditions of 14 workers occupationally exposed to lead, and the comparison of these results with those of a non-exposed control group, with similar age and sex, were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 micrograms/dl; while in the control group it was 10.9 micrograms/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant lessening in the formation of rosette in relation to the control group.
