RESUMO
Secondary and tertiary skin lesions of syphilis are infrequently biopsied and studied histologically. Examination of biopsy specimens from two patients, one with secondary and one with tertiary syphilis, revealed sarcoidal reactions, which caused confusion in the patients' diagnoses. The response to penicillin therapy in each patient was dramatic and contrary to the response anticipated in sarcoidosis. The histologic changes of secondary and tertiary syphilis are discussed.
Assuntos
Sarcoidose/diagnóstico , Dermatopatias/diagnóstico , Sífilis Cutânea/diagnóstico , Adulto , Idoso , Biópsia , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Penicilina G Benzatina/uso terapêutico , Penicilina G Procaína/uso terapêutico , Pele/patologia , Sorodiagnóstico da Sífilis , Sífilis Cutânea/tratamento farmacológico , Sífilis Cutânea/patologiaRESUMO
A 67-year-old female with localized bullous desquamative gingivitis is described. Ultrastructural studies of the perilesional area showed changes similar to those seen in cicatricial pemphigoid and epidermolysis bullosa acquisita.
Assuntos
Gengiva/ultraestrutura , Gengivite/patologia , Idoso , Vesícula/patologia , Doença Crônica , Epidermólise Bolhosa/complicações , Epidermólise Bolhosa/patologia , Feminino , Gengiva/patologia , Gengivite/etiologia , HumanosRESUMO
Acute myelomonocytic leukemia, a type of leukemic conversion that may be a manifestation of mycosis fungoides, developed in two patients with fairly typical courses of mycosis fungoides. The cases of five other patients with myelogenous leukemia as the terminal event of mycosis fungoides have been reported in the literature. A relationship to therapy could not be established, although all patients had had irradiation or chemotherapy or both.
