RESUMO
Schools across the United States and around the world canceled in-person classes beginning in March 2020 to contain the spread of the COVID-19 virus, a public health emergency. Many empirical pieces of research have demonstrated that educational institutions aid students' overall growth and studies have stressed the importance of prioritizing in-person learning to cultivate social values through education. Two years into the COVID-19 pandemic, policymakers and school administrators have been making plans to reopen schools. However, few scientific studies had been done to support planning classroom seating while complying with the social distancing policy. To ensure a safe return to campus, we designed a 'community-safe' method for classroom management that incorporates social distancing and computes seating capacity. In this paper, we present custom GIS tools developed for two types of classroom settings - classrooms with fixed seating and classrooms with movable seating. The fixed model tool is based on an optimized backtracking algorithm. Our flexible model tool can consider various classroom dimensions, fixtures, and a safe social distance. The tool is built on a python script that can be executed to calculate revised seating capacity to maintain a safe social distance for any defined space. We present a real-world implementation of the system at Eastern Michigan University, United States, where it was used to support campus reopening planning in 2020. Our proposed GIS-based technique could be applicable for seating planning in other indoor and outdoor settings. Supplementary Information: The online version contains supplementary material available at 10.1007/s43762-022-00040-3.
RESUMO
Citrate is the anticoagulant of choice for plateletpheresis. Citrate toxicity is common during plateletpheresis as citrate chelates calcium and causes hypocalcemia in donors. We have conducted this study to analyze the effects of routine citrate infusion during plateletpheresis on laboratory and clinical parameters. We also compared the dose of citrate delivered to donors during plateletpheresis using two different cell separators as Haemonetics MCS + and Trima Accel. The study was conducted on 50 plateletpheresis donors who were eligible for donation. Donor demographics and baseline parameters were recorded. Pre, mid and post-procedure blood samples were collected for hematological and biochemical analysis. We found a significant decrease in baseline iCa (1.23 ± 0.07 mmol/L) from start to mid-procedure (1.19 ± 0.006 mmol/L) which recovered at 30 min post procedure (1.2 ± 0.01 mmol/L). The incidence of citrate toxicity was 10%. In donors with citrate toxicity, the post-procedure recovery of iCa was not seen and there was a further decrease in iCa levels. We also found a significant fall in Hb and platelet count post plateletpheresis. We observed that lower PLT counts (< 200 × 103/µL) necessitated higher blood volume processing and therefore a higher anticoagulant (citrate) dose. The Trima Accel cell separator reached platelet target yield faster but with a higher citrate dose as compared to Hemonetics MCS + . Ionized calcium decreases significantly during plateletpheresis but recovers soon after the completion of the procedure. Serious adverse events were not observed during plateletpheresis. The mild citrate toxicity which occurred was easily managed by slowing the procedure and administering oral calcium to donors. Trima Accel and Hemonetics MCS + both collected platelets efficiently, with minimal donor discomfort.
