[Gastrodiscoidosis is a dangerous zoonosis].

The paper gives data on the helminthiasis--gastrodiscoidosis, a zoonotic disease caused by the trematode Gastrodiscoides hominis (Lewis et McConnall, 1876) parasitizing in the animal and human intestine in the endemic foci of both Russia and foreign countries. It also presents information on the morphology of the helminth, the biological cycle of development of the parasite and its habitat and spread, as well as its induced abnormalities and on the method of diagnosing of the disease.

[A course of coronary heart disease and quality of life in patients with varying depressive states]. / Osobennosti techeniia ischemicheskoi bolezni i kachestvo zhizni bol'nykh s depressivnymi rasstroistvami razlichnogo urovnia.

AIM: To study a course of coronary heart disease (CHD) in patients with depressive disorders. MATERIAL AND METHODS: The trial included 77 CHD patients aged 39 to 68 years (mean age 54.9 +/- 0.9 years), 40 (51.9%) of them had myocardial infarction. All the examinees had effort angina of functional class II-IV by criteria of the Canadian Cardiology Association. All the patients have undergone standard clinical examination, stress tests, coronaroangiography (n = 30), assessment of the degree of vegetative dystonia and quality of life. The patients were divided into two groups depending on the depression degree. RESULTS: CHD patients with manifest depression vs those with subclinical depression had a higher level of personality and reactive anxiety. They had neurotic and psychopathological personality alterations associated with more pronounced vegetative disorders. These patients suffered from more severe coronary atherosclerosis, more hospitalizations for the previous year, more myocardial infarctions, lower physical activity and quality of life. CONCLUSION: CHD patients with manifest depression have lower physical performance and quality of life though this is not confirmed at exercise tests.

[Automatic regulation and central hemodynamics in patients with postinfarct cardiosclerosis and heart failure]. / Vegetativnaia reguliatsiia i tsentral'naia gemodinamika pri ortoprobe u bol'nykh s postinfarktnym kardiosklerozom i serdechnoi nedostatochnost'iu.

The study was undertaken to examine the specific features of autonomic regulation and the parameters of central hemodynamics in patients with postinfarct cardiosclerosis (PICS) and circulatory insufficiency who had different types of left ventricular remodelling (LVR). Thirty-two patients with PICS and heart failure (HF) were examined. The autonomic status was studied, by analyzing cardiac rhythm variability (CRV) from 5-min resting cardiointervalograms and by the cardiovascular tests described by D. Y. Ewing; integral rheography was also performed. The patients were divided into 2 groups according to the type of LVR. Patients with PICS + HF and concentric LVR were found to have a more balanced autonomic circulatory regulation and a hemodynamic type that was more energetically efficient for the myocardium. Those with PICS + HF and eccentric LVR had a hemodynamic type that was less efficient for the myocardium, which was accompanied by the enhanced activity of the sympathetic nervous system (SNS) even at resting. Patients with PICS + HF, particularly in the presence of the latter's higher functional class and eccentric LVR, seemed to have desensitized adrenoceptors and impaired baroreflex activity, as appeared as no rise in peripheral vascular resistance with the enhanced sympathetic activity. The findings support the expediency of using beta-adrenoblockers in HF in patients with PICS, particularly with eccentric LVR. Analysis of cardiac rhythm variability is sufficiently informative in evaluating autonomic regulation and autonomic balance, SNS tone in particular, in patients with HF.