[The New Approaches to Organization of Medical Supplies Support of Patients in Hospital in Modern Conditions].

The article considers the results of complex scientific analysis of issues concerning medications' support of patients in hospital in modern conditions. The economic and social efficiency of proposed organizational methodological approaches to development of management of medications' support is demonstrated.

[The Medical Economic Analysis of Specialized Ophthalmologic Care within the Framework of Territorial Program of State Guarantees].

The article considers the results of study of economic issues related to application of intraocular lenses in medical organization in modern conditions. The main problems of conformity of possibilities to needs in health care are demonstrated.

[The evaluation of medicinal therapy under treatment of arterial hypertension in hospital].

The article presents the analysis of data of "Study on Global AGEing and Adult Health, 2007-2010" (SAGE) concerning subjective judging of health, prevalence of ischemic heart disease under different levels of arterial pressure in similar age groups. An attempt is made to evaluate spectrum of pharmaceuticals applied in treatment of patients with arterial pressure in hospital at the level of oblast hospital. According official statistics of Minzdrav of Russia, in 20102 prevalence of diseases characterized by higher arterial pressure amounted to 10.5% in adult population and to 22.3% in population older than able-bodied age. At the same time, according SAGE data, prevalence of various forms of hypertension disease in population older than 50 years amounted to 52.8%. That is, this pathology is often missed in conditions of mass medical network. Thereafter, patients receive no necessary medicinal therapy. The one or another treatment was provided to almost 94% of patients with hypertension disease diagnosed by physician. At that, among patients received treatment the normal levels of both systolic and diastolic pressure were established in less than 20% of patients with hypertension. Therefore, the issue of effectiveness of applied methods of correction of arterial hypertension become a matter of interest. The appropriate treatment of hypertension is a mean to decrease complications and as a result to diminish mortality of diseases of circulatory system.

[Role of the lateral hypothalamus in the genesis of somato-autonomic responses]. / Rol' lateral'nogo gipotalamusa v geneze somato-vegetativnykh reaktsii.

Coagulation of medial and lateral parts of the lateral hypothalamic area increases latency of responses and decreases respiration, arterial blood pressure and heart rate responses to stimulation of the hypothalamic ventromedial nucleus. Coagulation of the perifornical region of the lateral hypothalamus completely eliminates the above autonomic responses. A new rigid integration which is characterized with the increased number of correlated relations between separate components of somato-autonomic responses, was postulated after correlation analysis of somato-autonomic parameters during stimulation of hypothalamic ventromedial nucleus in animals with lateral hypothalamic lesions. The data suggest that somato-autonomic responses to stimulation of negative emotion sites of the hypothalamus are mediated by those brain structures which are under ascending excitatory influences of the lateral hypothalamus.

[Comparative characteristics of the self-stimulation response in rabbits following administration of angiotensin II into the cerebral ventricles and application to the conjunctiva]. / Sravnitel'naia kharakteristika reaktsii samorazdrazheniia u krolikov pri vvedenii angiotenzina II v zheludochki mozga i pri applikatsii na kon"iunktivu glaza.

Experiments on rabbits have shown that intraventricular administration of angiotensin II induces the dose-dependent suppression of the self-stimulation reaction after varying intervals. The same suppression of the self-stimulation in rabbits but after a greater interval is produced by the application of angiotensin aqueous solution to the eye conjunctiva. In both cases the amount of drinking reactions in the animals significantly rises after the oligopeptide administration as compared with controls. Examination of the time course of arterial pressure, respiration and ECG has shown that only intravenous injection of angiotensin II in doses of 500 ng provokes a temporary increase in arterial pressure, marked bradycardia and changes in respiration, whereas other routes of administration produce no changes in the characteristics studied.