Influence of smoking on audiological characteristics of hearing function.

Cigarette smoking and related diseases are global problem of health. Discussion regarding influence of smoking on hearing function has been continued about 20 years. The aim of our study was estimation of relation between smoking and development of cochlear neuritis. Research was conducted at Ltd. National Centre of ENT - Japaridze-Kevanishvili clinic and Ltd.Audiology National Center. The data were collected from September 2011 to December 2013. Cross- sectional observational study was carried out. 600 persons (mean age - 45.4±10.4) were enrolled in the research. After filling the informed consent persons were divided into two groups: smokers (300 smokers, apparently healthy persons, mean age 44.3±10.6 years) and control group (300 healthy non-smoker persons, mean age 46.5±10.2 years). All persons completed a questionnaire, which includes questions about smoking status too. The inclusion criterion in smokers group was a smoking habit during 5 years at least 10 cigarettes per day. Otoscopy and Acoustic impedance test (timpanometry, reflexometry, testing for Eustachian tube conductivity) were used for verification of outer and middle-ear normality. Pure Tone Audiometry was performed for hearing measure and identifies hearing nerve condition. Obtained results were statistically treated by the student's t-distribution. For minimal level of significance was taken p<0,05. In smokers group hearing loss was proved in 31.33% (94 persons) and in control group - in 17.34% (52 persons). Hearing-loss vs. normal-hearing ratio amounted hence to 0.46 (P<0.01) in the smokers group and to 0.21 (P<0.01) in the nonsmokers'. Hearing loss in smokers may be provided by different pathological mechanisms.

[Estimation of effectiveness of peroral mucolytic agents in treatment of inflammatory diseases of middle ear and paranasal sinusitis].

The aim of the work was estimation of perolar mucolytic agents in treatment of inflammatory diseases of middle ear and paranasal sinusitis. On the basis of research it was concluded that Sinupret reduced the necessity of grommet. Sinupret is the best systemic mucolytic in the treatment of inflammatory disease of middle ear and paranasal sinuses. To treat seros otitis media Sinupret was used as a monotherapy drug. In treatment of acute otitis media and sinusitis Sinupret is recommended in the third period of disease in combination with antibiotics.

[Surgical treatment of otitis media purulenta chronica].

Evolution of views on surgical treatment of otitis media purulenta chronica for the last decade and outcomes of this surgery in the last 5 years are reviewed. The authors made tympanoplastic operations in 220 patients. Function of the tympanic membrane recovered in 212 cases, a complete closure of the bone-air gap was observed in 89 patients; hearing improvement averaged 25 dB.