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Int J Gynaecol Obstet ; 76(3): 273-7, 2002 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11880130

RESUMO

OBJECTIVES: The objective of the study is to evaluate the effects of levonorgestrel transferred through breast milk on thyroid stimulating hormone (TSH) and luteinizing hormone (LH) levels in full breast-fed infants. METHODS: Forty healthy postpartum women and their male newborns were recruited for the study. Women were randomly allocated to two study groups: Group 1, IUD users and group 2, Norplant users. Blood and milk samples were collected on the day of IUD or Norplant insertion and 3 and 6 months later for TSH and levonorgestrel measurements. RESULTS: The results disclosed a significant decrease in TSH levels, and a negative relationship between LNG levels and TSH concentration in breast feeding infants at 3 months after implant insertion. The lowest TSH levels were observed at 6 months in the women from group 2. CONCLUSIONS: The overall data indicate that the LNG levels transferred to fully breast-fed infants through breast milk from Norplant users significantly modified their TSH levels.


Assuntos
Anticoncepcionais Femininos/metabolismo , Anticoncepcionais Femininos/farmacologia , Lactação , Levanogestrel/metabolismo , Levanogestrel/farmacologia , Hormônio Luteinizante/urina , Leite Humano/metabolismo , Tireotropina/sangue , Aleitamento Materno , Implantes de Medicamento , Feminino , Humanos , Técnicas Imunológicas , Lactente , Recém-Nascido , Masculino
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