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1.
Clin Transl Oncol ; 24(10): 1932-1939, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35653005

RESUMO

PURPOSE: To assess the value of a common clinical language in a multidisciplinary tumour board for spinal metastasis, using both the Rades score and the Spinal Instability Neoplastic Score (SINS) for multidisciplinary decision-making. METHODS: Retrospective study of 60 consecutive patients treated surgically for MSCC. The indication for surgery was done in a multidisciplinary board, basically according to SINS and RADES scores. Three prognostic groups were defined according to the Rades score: poor (Rades 1: 20-30 points), intermediate (Rades 2: 31-35), and good (Rades 3: 36-45). RESULTS: The 2-year overall survival (OS) rate was 50%, with median survival of 19 months. By Rades prognostic group (1, 2, 3), median OS was 6 months, 15 months, and not reached, respectively. OS rates at 6 months (Rades 1, 2, 3) were 51, 69, and 74.1%, respectively. Within the Rades 1 group, 6-month survival in patients with new-onset cancer was 68 vs. 40% in those with a known primary. The overall complication rate ≥ grade 3 was 23.3% (n = 14). In patients who underwent urgent surgery (< 48 h), the complication rate was 45.5% (5/11) versus 18.3% (9/49) in the planned surgeries. CONCLUSIONS: Our findings supports the utility of using a common language in multidisciplinary tumour board for spinal metastasis. The 2-year OS rate in this series was 50%, which is the highest OS reported to date in this population. In the poor prognosis subgroup (Rades 1), OS at 6 months was higher in patients with new-onset cancer versus those with a known primary (68 vs. 40%). These findings suggest that surgery should be the first treatment option in patients with MSCC as first symptom of cancer although a predicted poor prognosis.


Assuntos
Compressão da Medula Espinal , Neoplasias da Coluna Vertebral , Humanos , Idioma , Prognóstico , Estudos Retrospectivos
2.
Neurocirugía (Soc. Luso-Esp. Neurocir.) ; 30(2): 81-86, mar.-abr. 2019. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-182006

RESUMO

Anterior cervical discectomy has a low non-mechanical complication rate. In our literature review, we found 7 cases of delayed surgical site infection. We report a case of cervical prevertebral abscess due to Propionibacterium acnes 2 years after discectomy and arthroplasty, with a beta-2-transferrin false positive test as a complementary highlighted finding. We discuss the diagnosis and etiology of this rare delayed infectious complication


La discectomía cervical anterior tiene una baja tasa de complicaciones no mecánicas. En la revisión de la literatura, encontramos 7 casos de infección diferida del sitio quirúrgico. Presentamos un caso de absceso cervical prevertebral secundario a Propionibacterium acnes 2 años después de la cirugía, asociado a un falso positivo del test de beta-2-transferrina como hallazgo complementario a destacar, y discutimos el diagnóstico y la etiología de esta rara complicación infecciosa diferida


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Infecção da Ferida Cirúrgica/etiologia , Plexo Cervical/cirurgia , Artroplastia/métodos , Tempo para o Tratamento , Abscesso/complicações , Infecção da Ferida Cirúrgica/complicações , Complicações Pós-Operatórias/prevenção & controle , Fatores de Tempo , Cicatrização
3.
Neurocirugia (Astur : Engl Ed) ; 30(2): 81-86, 2019.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-29627290

RESUMO

Anterior cervical discectomy has a low non-mechanical complication rate. In our literature review, we found 7 cases of delayed surgical site infection. We report a case of cervical prevertebral abscess due to Propionibacterium acnes 2 years after discectomy and arthroplasty, with a beta-2-transferrin false positive test as a complementary highlighted finding. We discuss the diagnosis and etiology of this rare delayed infectious complication.


Assuntos
Abscesso/diagnóstico por imagem , Artroplastia , Vértebras Cervicais/cirurgia , Discotomia , Infecções por Bactérias Gram-Positivas/diagnóstico por imagem , Deslocamento do Disco Intervertebral/cirurgia , Propionibacterium acnes , Fusão Vertebral , Infecção da Ferida Cirúrgica/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Tempo
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